The Structure of Biological Science

The Structure of Biological Science

Author: Alexander Rosenberg

Publisher: Cambridge University Press

Published: 1985-01-25

Total Pages: 300

ISBN-13: 9780521275613

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Preface p. ix Chapter 1 Biology and Its Philosophy p. 2 1.1 The Rise of Logical Positivism p. 2 1.2 The Consequences for Philosophy p. 4 1.3 Problems of Falsifiability p. 6 1.4 Philosophy of Science Without Positivism p. 8 1.5 Speculation and Science p. 10 Introduction to the Literature p. 11 Chapter 2 Autonomy and Provincialism p. 13 2.1 Philosophical Agendas versus Biological Agendas p. 13 2.2 Motives for Provincialism and Autonomy p. 18 2.3 Biological Philosophies p. 21 2.4 Tertium Datur? p. 25 2.5 The Issues in Dispute p. 30 2.6 Steps in the Argument p. 34 Introduction to the Literature p. 35 Chapter 3 Teleology and the Roots of Autonomy p. 37 3.1 Functional Explanations in Molecular Biology p. 39 3.2 The Search for Functions p. 43 3.3 Functional Laws p. 47 3.4 Directively Organized Systems p. 52 3.5 The Autonomy of Teleological Laws p. 59 3.6 The Metaphysics and Epistemology of Functional Explanation p. 62 3.7 Functional Explanation Will Always Be with Us p. 65 Introduction to the Literature p. 67 Chapter 4 Reductionism and the Temptation of Provincialism p. 69 4.1 Motives for Reductionism p. 69 4.2 A Triumph of Reductionism p. 73 4.3 Reductionism and Recombinant DNA p. 84 4.4 Antireductionism and Molecular Genetics p. 88 4.5 Mendel's Genes and Benzer's Cistrons p. 93 4.6 Reduction Obstructed p. 97 4.7 Qualifying Reductionism p. 106 4.8 The Supervenience of Mendelian Genetics p. 11 4.9 Levels of Organization p. 117 Introduction to the Literature p. 119 Chapter 5 The Structure of Evolutionary Theory p. 121 5.1 Is There an Evolutionary Theory? p. 122 5.2 The Charge of Tautology p. 126 5.3 Population Genetics and Evolution p. 130 5.4 Williams's Axiomatization of Evolutionary Theory p. 136 5.5 Adequacy of the Axiomatization p. 144 Introduction to the Literature p. 152 Chapter 6 Fitness p. 154 6.1 Fitness Is Measured by Its Effects p. 154 6.2 Fitness As a Statistical Propensity p. 160 6.3 The Supervenience of Fitness p. 164 6.4 The Evidence for Evolution p. 169 6.5 The Scientific Context of Evolutionary Theory p. 174 Introduction to the Literature p. 179 Chapter 7 Species p. 180 7.1 Operationalism and Theory in Taxonomy p. 182 7.2 Essentialism--For and Against p. 187 7.3 The Biological Species Notion p. 191 7.4 Evolutionary and Ecological Species p. 197 7.5 Species Are Not Natural Kinds p. 201 7.6 Species As Individuals p. 204 7.7 The Theoretical Hierarchy of Biology p. 212 7.8 The Statistical Character of Evolutionary Theory p. 216 7.9 Universal Theories and Case Studies p. 219 Introduction to the Literature p. 225 Chapter 8 New Problems of Functionalism p. 226 8.1 Functionalism in Molecular Biology p. 228 8.2 The Panglossian Paradigm p. 235 8.3 Aptations, Exaptations, and Adaptations p. 243 8.4 Information and Action Among the Macromolecules p. 246 8.5 Metaphors and Molecules p. 255 Bibliography p. 266 Index p. 273.


Levels of Organization in the Biological Sciences

Levels of Organization in the Biological Sciences

Author: Daniel S. Brooks

Publisher: MIT Press

Published: 2021-08-24

Total Pages: 337

ISBN-13: 0262045338

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Scientific philosophers examine the nature and significance of levels of organization, a core structural principle in the biological sciences. This volume examines the idea of levels of organization as a distinct object of investigation, considering its merits as a core organizational principle for the scientific image of the natural world. It approaches levels of organization--roughly, the idea that the natural world is segregated into part-whole relationships of increasing spatiotemporal scale and complexity--in terms of its roles in scientific reasoning as a dynamic, open-ended idea capable of performing multiple overlapping functions in distinct empirical settings. The contributors--scientific philosophers with longstanding ties to the biological sciences--discuss topics including the philosophical and scientific contexts for an inquiry into levels; whether the concept can actually deliver on its organizational promises; the role of levels in the development and evolution of complex systems; conditional independence and downward causation; and the extension of the concept into the sociocultural realm. Taken together, the contributions embrace the diverse usages of the term as aspects of the big picture of levels of organization. Contributors Jan Baedke, Robert W. Batterman, Daniel S. Brooks, James DiFrisco, Markus I. Eronen, Carl Gillett, Sara Green, James Griesemer, Alan C. Love, Angela Potochnik, Thomas Reydon, Ilya Tëmkin, Jon Umerez, William C. Wimsatt, James Woodward


Fundamentals of Molecular Structural Biology

Fundamentals of Molecular Structural Biology

Author: Subrata Pal

Publisher: Academic Press

Published: 2019-09-02

Total Pages: 518

ISBN-13: 0128148551

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Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease


Concepts of Biology

Concepts of Biology

Author: Samantha Fowler

Publisher:

Published: 2017-12-30

Total Pages: 624

ISBN-13: 9781680921021

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Concepts of Biology is designed for the introductory biology course for nonmajors taught at most two- and four-year colleges. The scope, sequence, and level of the program are designed to match typical course syllabi in the market. Concepts of Biology includes interesting applications, features a rich art program, and conveys the major themes of biology. The images in this textbook are grayscale.


Biological Materials Science

Biological Materials Science

Author: Marc André Meyers

Publisher: Cambridge University Press

Published: 2014-07-31

Total Pages: 647

ISBN-13: 1107010454

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Takes a materials science approach, correlating structure-property relationships with function across a broad range of biological materials.


Foundations of Structural Biology

Foundations of Structural Biology

Author: Leonard J. Banaszak

Publisher: Elsevier

Published: 2000-02-08

Total Pages: 180

ISBN-13: 0080521843

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Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features* Explains how to use coordinate databases and atomic coordinates of biological macromolecules* Teaches the skills of stereoviewing* Contains computer-generated stereographics* Describes the principles of symmetry and handedness in proteins and DNA* Introduces metal and lipid binding proteins and DNA-protein interactions* Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions


Biological Science

Biological Science

Author: Jon (Emeritus Professor of Bioscience Education Scott, Emeritus Professor of Bioscience Education University of Leicester)

Publisher: Oxford University Press

Published: 2022-06-24

Total Pages: 1416

ISBN-13: 019878368X

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Biological Science: Exploring the Science of Life responds to the key needs of lecturers and their students by placing a clear central narrative, carefully-structured active learning, and confidence with quantitative concepts and scientific enquiry central to its approach.Written by a team of dedicated and passionate academics, and shaped by feedback from over 55 institutions, its straightforward narrative, reinforced by key concept overview videos for every chapter, communicate key ideas clearly: the right information is provided at the right time, and at the rightdepth.Its pause and think features, self-check quizzes, and graded end of chapter questions, augmented by flashcards of key terms, directly support active learning. The combination of narrative text and learning features promote a rich, active learning experience: read, watch, and do.Its combination of Quantitative Toolkits, Scientific Process panels, and the Life and its Exploration chapters provide more insight and support than any other general biology text; they prepare students to engage with this quantitative and experimental discipline with confidence, and set them on apath for success throughout their future studies.With coverage that spans the full scale of biological science - from molecule to ecosystem - and with an approach that fully supports flexible, self-paced learning, Biological Science: Exploring the Science of Life will set you on a path towards a deeper understanding of the key concepts inbiology, and a greater appreciation of biology as a dynamic experimental science.Digital formats and resourcesBiological Science: Exploring the Science of Life is available for students and institutions to purchase in a variety of formats.The enhanced ebook is enriched with features that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks- Key concepts videos support students from the start of every chapter and as they make their way through every Module.- Self-check questions at the end of each chapter section give students quick and formative feedback, building their confidence and comprehension as they study and revise.- Quantitative skills video screencasts help students to master the foundational skills required by this discipline.- Interactive figures give students the control they need to step through, and gain mastery over, key concepts.- Per-chapter flashcard glossaries help students to recall the key terms and concepts on which further study can be built.


The Structure of Biological Membranes

The Structure of Biological Membranes

Author: Philip L. Yeagle

Publisher: CRC Press

Published: 2011-07-18

Total Pages: 398

ISBN-13: 1439809585

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Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition pro