Immunization Safety Review
Immunization Safety Review

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2004-09-30

Total Pages: 214

ISBN-13: 030909237X

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This eighth and final report of the Immunization Safety Review Committee examines the hypothesis that vaccines, specifically the measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines, are causally associated with autism. The committee reviewed the extant published and unpublished epidemiological studies regarding causality and studies of potential biologic mechanisms by which these immunizations might cause autism. Immunization Safety Review: Vaccines and Autism finds that the body of epidemiological evidence favors rejection of a causal relationship between thimerosal-containing vaccines and autism. The book further finds that potential biological mechanisms for vaccine-induced autism that have been generated to date are only theoretical. It recommends a public health response that fully supports an array of vaccine safety activities and recommends that available funding for autism research be channeled to the most promising areas. The book makes additional recommendations regarding surveillance and epidemiological research, clinical studies, and communication related to these vaccine safety concerns.

Immunization Safety Review
Immunization Safety Review

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2003-11-26

Total Pages: 118

ISBN-13: 0309168910

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The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.

Adverse Effects of Vaccines
Adverse Effects of Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-04-26

Total Pages: 894

ISBN-13: 0309214351

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In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

The Childhood Immunization Schedule and Safety
The Childhood Immunization Schedule and Safety

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2013-04-27

Total Pages: 237

ISBN-13: 0309267021

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Vaccines are among the most safe and effective public health interventions to prevent serious disease and death. Because of the success of vaccines, most Americans today have no firsthand experience with such devastating illnesses as polio or diphtheria. Health care providers who vaccinate young children follow a schedule prepared by the U.S. Advisory Committee on Immunization Practices. Under the current schedule, children younger than six may receive as many as 24 immunizations by their second birthday. New vaccines undergo rigorous testing prior to receiving FDA approval; however, like all medicines and medical interventions, vaccines carry some risk. Driven largely by concerns about potential side effects, there has been a shift in some parents' attitudes toward the child immunization schedule. The Childhood Immunization Schedule and Safety identifies research approaches, methodologies, and study designs that could address questions about the safety of the current schedule. This report is the most comprehensive examination of the immunization schedule to date. The IOM authoring committee uncovered no evidence of major safety concerns associated with adherence to the childhood immunization schedule. Should signals arise that there may be need for investigation, however, the report offers a framework for conducting safety research using existing or new data collection systems.

Vaccines, Autism, and Childhood Disorders
Vaccines, Autism, and Childhood Disorders

Author: Neil Z. Miller

Publisher:

Published: 2003

Total Pages: 0

ISBN-13: 9781881217329

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Autism is a complex disability resulting in brain damage, immune dysfunction, self-destructive behaviour patterns, and unresponsiveness to other people. It often strikes following an early childhood of apparently normal development. Many parents believe that childhood vaccines, especially MMR, are responsible. Some studies confirm that vaccines may cause autism in certain predisposed children. Health authorities, however, deny that autism is linked to vaccines. Some studies support their position. Congress recently held several hearings to investigate the causes of, and cures for, this growing epidemic. The testimony hints at a medical cover-up. This book chronicles Congressional efforts to expose the truth, summarises vaccine studies on both sides of the debate, and provides parents with crucial data to make informed decisions.

Callous Disregard
Callous Disregard

Author: Andrew J. Wakefield

Publisher: Simon and Schuster

Published: 2017-11-21

Total Pages: 380

ISBN-13: 1510729674

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Callous Disregard is the account of how a doctor confronted first a disease and then the medical system that sought and still seeks to deny that disease, leaving millions of children to suffer and a world at risk. In 1995, Dr. Andrew Wakefield came to a fork in the road. As an academic gastroenterologist at the Royal Free School of Medicine and the University of London, he was confronted by a professional challenge and a moral choice. Previously healthy children were, according to their parents, regressing into autism and developing intestinal problems. Many parents blamed the MMR vaccine. Trusting his medical training, the parental narrative, and, above all, the instinct of mothers for their children?s well-being, he chose what would become a very difficult road. Dr. Wakefield provides the facts and an explanation of the problem that confronted him and his colleagues fifteen years ago. He does this in a detailed forensic analysis of the lies, obfuscation, cover-up, and dystopian science and medicine that panders to commercial interests at the expense of your children.

The Panic Virus
The Panic Virus

Author: Seth Mnookin

Publisher: Simon and Schuster

Published: 2012-01-03

Total Pages: 466

ISBN-13: 1439158657

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A searing account of how vaccine opponents have used the media to spread their message of panic, despite no scientific evidence to support them.

Vaccines & Your Child
Vaccines & Your Child

Author: Paul A. Offit

Publisher: Columbia University Press

Published: 2011

Total Pages: 259

ISBN-13: 0231153074

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Two leading advocates for modern vaccines answer parents' numerous questions about the underlying science of modern vaccines and the value of childhood immunization, while addressing parents' concerns about vaccine safety.

Vaccines Did Not Cause Rachel's Autism
Vaccines Did Not Cause Rachel's Autism

Author: Peter J. Hotez

Publisher: Johns Hopkins University Press

Published: 2020-11-17

Total Pages: 240

ISBN-13: 1421439808

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Internationally renowned medical scientist, frequent media contributor, and autism dad Dr. Peter J. Hotez explains why vaccines do not cause autism. In 1994, Peter J. Hotez's nineteen-month-old daughter, Rachel, was diagnosed with autism. Dr. Hotez, a pediatrician-scientist who develops vaccines for neglected tropical diseases affecting the world's poorest people, became troubled by the decades-long rise of the influential anti-vaccine community and its inescapable narrative around childhood vaccines and autism. In Vaccines Did Not Cause Rachel's Autism, Hotez draws on his experiences as a pediatrician, vaccine scientist, and father of an autistic child. Outlining the arguments on both sides of the debate, he examines the science that refutes the concerns of the anti-vaccine movement, debunks current conspiracy theories alleging a cover-up by the Centers for Disease Control and Prevention, and critiques the scientific community's failure to effectively communicate the facts about vaccines and autism to the general public, all while sharing his very personal story of raising a now-adult daughter with autism. A uniquely authoritative account, this important book persuasively provides evidence for the genetic basis of autism and illustrates how the neurodevelopmental pathways of autism are under way before birth. Dr. Hotez reminds readers of the many victories of vaccines over disease while warning about the growing dangers of the anti-vaccine movement, especially in the United States and Europe. Now, with the anti-vaccine movement reenergized in our COVID-19 era, this book is especially timely. Vaccines Did Not Cause Rachel's Autism is a must-read for parent groups, child advocates, teachers, health-care providers, government policymakers, health and science policy experts, and anyone caring for a family member or friend with autism. "When Peter Hotez—an erudite, highly trained scientist who is a true hero for his work in saving the world's poor and downtrodden—shares his knowledge and clinical insights along with his parental experience, when his beliefs in the value of what he does are put to the test of a life guiding his own child's challenges, then you must pay attention. You should. This book brings to an end the link between autism and vaccination."—from the foreword by Arthur L. Caplan, NYU School of Medicine