The Organic Chemistry of Drug Design and Drug Action
The Organic Chemistry of Drug Design and Drug Action

Author: Richard B. Silverman

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 650

ISBN-13: 0080513379

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Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

General and Molecular Pharmacology
General and Molecular Pharmacology

Author: Francesco Clementi

Publisher: John Wiley & Sons

Published: 2015-07-01

Total Pages: 784

ISBN-13: 1118768590

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With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book

Introduction to Basics of Pharmacology and Toxicology
Introduction to Basics of Pharmacology and Toxicology

Author: Gerard Marshall Raj

Publisher: Springer Nature

Published: 2019-11-16

Total Pages: 410

ISBN-13: 9813297794

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This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.

Oral Drug Absorption
Oral Drug Absorption

Author: Jennifer B. Dressman

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 432

ISBN-13: 1420077341

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Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an

Drug Metabolism in Diseases
Drug Metabolism in Diseases

Author: Wen Xie

Publisher: Academic Press

Published: 2016-09-12

Total Pages: 296

ISBN-13: 0128029633

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Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology. - Written and edited by leaders in drug metabolism from academia and industry - Covers important topics, such as pharmacogenomics, drug metabolism in transplant patients, xenobiotic receptors, drug metabolism in geriatric and pediatric populations, and more - Highlights topics of importance in drug discovery and development, and for safe and effective drug use in the clinic

Delmar Nurse's Drug Handbook 2010 Edition (Book Only)
Delmar Nurse's Drug Handbook 2010 Edition (Book Only)

Author: George R. Spratto

Publisher: Cengage Learning

Published: 2009-06

Total Pages: 0

ISBN-13: 9781111319328

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Put the latest edition of today's most trusted drug reference guide in your hands with DELMAR NURSE'S DRUG HANDBOOK(TM) 2012 EDITION. This essential resource clearly describes the most important information for over 770 of the latest and most common FDA-approved drugs. Each entry provides a wealth of information concerning drug action, pharmacokinetics, dosage, interactions, and contraindications. Clear guidelines are also provided for administration of drugs, communication with clients, and nursing considerations. This edition offers even more convenience with an iPhone/iPod touch Application that places the complete drug guide at your fingertips with enhanced search options.

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases
Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Author: Solomon Habtemariam

Publisher: Academic Press

Published: 2019-06-08

Total Pages: 1182

ISBN-13: 0081029233

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Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. - Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level - Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases - Examines the pharmacological findings on medicinal foods, including available clinical trials

Small Animal Clinical Pharmacology E-Book
Small Animal Clinical Pharmacology E-Book

Author: Jill E. Maddison

Publisher: Elsevier Health Sciences

Published: 2008-02-13

Total Pages: 600

ISBN-13: 0702037257

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The eBook version of this title gives you access to the complete book content electronically*. Evolve eBooks allows you to quickly search the entire book, make notes, add highlights, and study more efficiently. Buying other Evolve eBooks titles makes your learning experience even better: all of the eBooks will work together on your electronic "bookshelf", so that you can search across your entire library of Veterinary Medicine eBooks. *Please note that this version is the eBook only and does not include the printed textbook. Alternatively, you can buy the Text and Evolve eBooks Package (which gives you the printed book plus the eBook). Please scroll down to our Related Titles section to find this title. Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. - Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance - Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders - Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject - All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text

The Specific Action of Drugs
The Specific Action of Drugs

Author: Alexander Burness

Publisher: BoD – Books on Demand

Published: 2023-05-18

Total Pages: 230

ISBN-13: 3382505584

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Reprint of the original, first published in 1874. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.