Originally published in 1971. Discoveries in modern biology can radically change human life as we know it. As our understanding of living processes, such as inheritance, grows, so do the possibilities of applying these results for good and evil, such as the treatment of disease, the control of ageing, behaviour and genetic engineering. These discoveries and their implications are discussed by some of the world’s leading biologists.
Originally published in 1971. Discoveries in modern biology can radically change human life as we know it. As our understanding of living processes, such as inheritance, grows, so do the possibilities of applying these results for good and evil, such as the treatment of disease, the control of ageing, behaviour and genetic engineering. These discoveries and their implications are discussed by some of the world’s leading biologists.
The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
The Irish potato famine and birth of plant pathology. Introduction to the fungi and their life cycles. Pathogens and quarantines. Bacteria. Genes and genetic engineering. Plant disease epidemics and their management. Pesticides. Soil, the rhizosphere, and soilborne patogens. Fungi in food: natural poisons and gourmet delicacies. Rusts. Dying trees and parasitic plants. Viruses and more recently discovered pathogens. Environmental diseases and problemes. Pant diseases in a hungry world. Glossary. Figure credits. Index.
Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
In the early decades of the twentieth century, engagement with science was commonly used as an emblem of modernity. This phenomenon is now attracting increasing attention in different historical specialties. Being Modern builds on this recent scholarly interest to explore engagement with science across culture from the end of the nineteenth century to approximately 1940. Addressing the breadth of cultural forms in Britain and the western world from the architecture of Le Corbusier to working class British science fiction, Being Modern paints a rich picture. Seventeen distinguished contributors from a range of fields including the cultural study of science and technology, art and architecture, English culture and literature examine the issues involved. The book will be a valuable resource for students, and a spur to scholars to further examination of culture as an interconnected web of which science is a critical part, and to supersede such tired formulations as 'Science and culture'.
In 1969, Jon Beckwith and his colleagues succeeded in isolating a gene from the chromosome of a living organism. Announcing this startling achievement at a press conference, Beckwith took the opportunity to issue a public warning about the dangers of genetic engineering. Jon Beckwith's book, the story of a scientific life on the front line, traces one remarkable man's dual commitment to scientific research and social responsibility over the course of a career spanning most of the postwar history of genetics and molecular biology. A thoroughly engrossing memoir that recounts Beckwith's halting steps toward scientific triumphs--among them, the discovery of the genetic element that turns genes on--as well as his emergence as a world-class political activist, Making Genes, Making Waves is also a compelling history of the major controversies in genetics over the last thirty years. Presenting the science in easily understandable terms, Beckwith describes the dramatic changes that transformed biology between the late 1950s and our day, the growth of the radical science movement in the 1970s, and the personalities involved throughout. He brings to light the differing styles of scientists as well as the different ways in which science is presented within the scientific community and to the public at large. Ranging from the travails of Robert Oppenheimer and the atomic bomb to the Human Genome Project and recent "Science Wars," Beckwith's book provides a sweeping view of science and its social context in the latter half of the twentieth century.
Recent research has emphasized that socially transmitted information may affect both the gene pool and the phenotypes of individuals and populations, and that an improved understanding of evolutionary issues is beneficial to those working towards the improvement of human health. In response to a growing interest across disciplines for information regarding the contribution of social behavior to a range of biological outcomes, Social Information Transmission and Human Biology connects the work of evolutionary theorists and those dealing with practical issues in human health and demographics. Combining evolutionary models with biomedical research, authors from various disciplines look at how human behavior influences health, and how reproductive fitness sheds light on the processes that shaped the evolution of human behavior. Both academic and medical researchers will find much useful insight in this text.
The impact agenda is set to shape the way in which social scientists prioritise the work they choose to pursue, the research methods they use and how they publish their findings over the coming decade, but how much is currently known about how social science research has made a mark on society? Based on a three year research project studying the impact of 360 UK-based academics on business, government and civil society sectors, this groundbreaking new book undertakes the most thorough analysis yet of how academic research in the social sciences achieves public policy impacts, contributes to economic prosperity, and informs public understanding of policy issues as well as economic and social changes. The Impact of the Social Sciences addresses and engages with key issues, including: identifying ways to conceptualise and model impact in the social sciences developing more sophisticated ways to measure academic and external impacts of social science research explaining how impacts from individual academics, research units and universities can be improved. This book is essential reading for researchers, academics and anyone involved in discussions about how to improve the value and impact of funded research.
