The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition

The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition

Author: Learn-Han Lee

Publisher: Frontiers Media SA

Published: 2020-03-27

Total Pages: 312

ISBN-13: 2889636399

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There is a large market demand for new drugs. The existing chronic or common ailments without cures, development of new diseases with unknown causes, and the widespread existence of antibiotic-resistant pathogens, have driven this field of research further by looking at all potential sources of natural products. To date, microbes have made a significant contribution to the health and well-being of people globally. The discoveries of useful metabolites produced by microbes have resulted in a significant proportion of pharmaceutical products in today’s market. Therefore, the investigation and identification of bioactive compound(s) producing microbes is always of great interest to researchers. Actinobacteria are one of the most important and efficient groups of natural metabolite producers. Among the numerous genera, Streptomyces have been recognized as prolific producers of useful natural compounds, as they provide more than half of the naturally-occurring antibiotics isolated to-date and continue to emerge as the primary source of new bioactive compounds. Certainly, these potentials have attracted ample research interest and a wide range of biological activities have been subsequently screened by researchers with the utilization of different In vitro and In vivo model of experiments. Literature evidence has shown that a significant number of interesting compounds produced by Actinobacteria were exhibiting either strong anticancer or neuroprotective activity. The further in depth studies have then established the modulation of apoptotic pathway was involved in those observed bioactivities. These findings indirectly prove the biopharmaceutical potential possessed by Actinobacteria and at the same time substantiate the importance of diverse pharmaceutical evaluations on Actinobacteria. In fact, many novel compounds discovered from Actinobacteria with strong potential in clinical applications have been developed into new drugs by pharmaceutical companies. Together with the advancement in science and technology, it is predicted that there would be an expedition in discoveries of new bioactive compounds producing Actinobacteria from various sources, including soil and marine sources. In light of these current needs, and great interest in the scope of this research, this book seeks to contribute on the investigation of different biological active compound(s) producing actinobacteria which are exhibiting antimicrobial, antioxidant, neuroprotective, anticancer activities and similar.


Actinobacteria

Actinobacteria

Author: Dharumadurai Dhanasekaran

Publisher: BoD – Books on Demand

Published: 2016-02-11

Total Pages: 401

ISBN-13: 9535122487

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This book presents an introductory overview of Actinobacteria with three main divisions: taxonomic principles, bioprospecting, and agriculture and industrial utility, which covers isolation, cultivation methods, and identification of Actinobacteria and production and biotechnological potential of antibacterial compounds and enzymes from Actinobacteria. Moreover, this book also provides a comprehensive account on plant growth-promoting (PGP) and pollutant degrading ability of Actinobacteria and the exploitation of Actinobacteria as ecofriendly nanofactories for biosynthesis of nanoparticles, such as gold and silver. This book will be beneficial for the graduate students, teachers, researchers, biotechnologists, and other professionals, who are interested to fortify and expand their knowledge about Actinobacteria in the field of Microbiology, Biotechnology, Biomedical Science, Plant Science, Agriculture, Plant pathology, Environmental Science, etc.


Actinobacteria in Special and Extreme Habitats: Diversity, Function Roles and Environmental Adaptations

Actinobacteria in Special and Extreme Habitats: Diversity, Function Roles and Environmental Adaptations

Author: Sheng Qin

Publisher: Frontiers Media SA

Published: 2016-11-09

Total Pages: 231

ISBN-13: 2889450139

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Actinobacteria are highly diverse prokaryotes that are ubiquitous in soil, freshwater and marine ecosystems. Although various studies have focused on the ecology of this phylum, data are still scant on the diversity, abundance and ecology of actinobacteria endemic to special and extreme environments, such as gut, plant, alkaline saline soil, deep sea sediments, hot springs and other habitats. Actinobacteria are well-known producers of a vast array of secondary metabolites, many of which have useful applications in medicine and agriculture. Furthermore, actinobacteria also have diverse functions in different environments apart from antibiotic production. For example, actinobacteria are reported to contribute to the break-down and recycling of organic compounds. They play a significant role in fixation of nitrogen, improvement plant growth, biodegradation, bioremediation and environmental protection. Therefore, understanding the actinobacterial diversity and distribution in such special environments is important in deciphering the ecological roles of these microorganisms and for biotechnological bioprospecting. Recent advances in cultivation, DNA sequencing technologies and -omics (metagenomics, metaproteomics etc) methods have greatly contributed to the rapid advancement of our understanding of microbial diversity, function and they interactions with environment. Furthermore, comparative genomic studies can provide overall information about actinobacterial speciation, evolution, metabolism and environment adaptation mechanisms. This research topic comprising reviews and original articles highlights the recent advances regarding the unexpectedly diverse/rare group of actinobacteria with special selective isolation methods or culture-independent methods, as well as their biological activities, ecophysiologica function and mechanisms from diverse special and extreme environments.


WICSTH 2022

WICSTH 2022

Author: Nasib Marbun

Publisher: European Alliance for Innovation

Published: 2023-04-03

Total Pages: 209

ISBN-13: 1631903896

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2nd Warmadewa International Conference on Science, Technology and Humanity will be an annual event hosted by Warmadewa Research Institution, Universitas Warmadewa. This year (2022), will be second time WICSTH will be held on 28 - 29 October 2022 at Auditorium Widya Sabha, Universitas Warmadewa Denpasar-Bali, Indonesia. In the direction of generating community’s welfare through the implementation of higher education research in supporting SDGS, this is a momentum to bring together various critical views and thoughts from various fields of science related to strategies that can be done in developing and solving the issues in Science, technology and humanity study. The conference invites delegates from across Indonesia and is usually attended by more than 100 participants from university academics, researchers, practitioners, and professionals across a wide range of industries.


Actinobacteria: Prolific Producers of Bioactive Metabolites

Actinobacteria: Prolific Producers of Bioactive Metabolites

Author: Learn-Han Lee

Publisher: Frontiers Media SA

Published: 2020-12-09

Total Pages: 138

ISBN-13: 2889660877

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.


Recent Developments in Applied Microbiology and Biochemistry

Recent Developments in Applied Microbiology and Biochemistry

Author: Viswanath Buddolla

Publisher: Academic Press

Published: 2020-10-15

Total Pages: 382

ISBN-13: 0128214074

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Recent Developments in Applied Microbiology and Biochemistry, Vol. 2, provides a comprehensive treatment and understanding on application oriented microbial concepts, giving readers insights into recent developments in microbial biotechnology and medical, agricultural and environmental microbiology. - Discusses microbial proteome analyses and their importance in medical microbiology - Explores emerging trends in the prevention of current global health problems, such as cancer, obesity and immunity - Shows recent approaches in the production of novel enzymes from environmental samples by enrichment culture and metagenomics approaches - Guides readers through the status and recent developments in analytical methods for the detection of foodborne microorganisms


Biology and Biotechnology of Actinobacteria

Biology and Biotechnology of Actinobacteria

Author: Joachim Wink

Publisher: Springer

Published: 2017-10-19

Total Pages: 398

ISBN-13: 3319603396

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This book provides in-depth insights into the biology, taxonomy, genetics, physiology and biotechnological applications of Actinobacteria. It especially focuses on the latter, reviewing the wide variety of actinobacterial bioactive molecules and their benefits for diverse industrial applications such as agriculture, aquaculture, biofuel production and food technology. Actinobacteria are one of the most promising sources of small bioactive molecules and it is estimated that only a small percentage of actinobacterial bioactive chemicals have been discovered to date. Identifying new diverse gene clusters of biotechnological relevance in the genome of Actinobacteria will be crucial to developing advanced applications for pharmaceutical, industrial and agricultural purposes. The book offers a unique resource for all graduate students, researchers and practitioners in the fields of microbiology, microbial biotechnology, and the genetic engineering of Actinobacteria.


Actinobacteria and Myxobacteria

Actinobacteria and Myxobacteria

Author: Joachim Wink

Publisher: MDPI

Published: 2020-12-15

Total Pages: 271

ISBN-13: 3039435299

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Bacterial infections cause millions of deaths globally, particularly in children and the elderly, and four of the 10 leading causes of death are infectious diseases in low- and middle-income countries. The continuous use of antibiotics has resulted in multi-resistant bacterial strains all over the world, such as Community-associated Methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum β-lactamases (ESBLs), and, as expected, hospitals have become breeding grounds for human-associated microorganisms, especially in critical care units.


Desk Encyclopedia of Microbiology

Desk Encyclopedia of Microbiology

Author: Moselio Schaechter

Publisher: Academic Press

Published: 2010-04-19

Total Pages: 1277

ISBN-13: 0080961282

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The Desk Encyclopedia of Microbiology, Second Edition is a single-volume comprehensive guide to microbiology for the advanced reader. Derived from the six volume e-only Encyclopedia of Microbiology, Third Edition, it bridges the gap between introductory texts and specialized reviews. Covering topics ranging from the basic science of microbiology to the current "hot" topics in the field, it will be invaluable for obtaining background information on a broad range of microbiological topics, preparing lectures and preparing grant applications and reports. - The most comprehensive single-volume source providing an overview of microbiology to non-specialists - Bridges the gap between introductory texts and specialized reviews - Provides concise and general overviews of important topics within the field making it a helpful resource when preparing for lectures, writing reports, or drafting grant applications


Antimicrobials

Antimicrobials

Author: Dharumadurai Dhanasekaran

Publisher: CRC Press

Published: 2015-12-01

Total Pages: 532

ISBN-13: 149871563X

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Antimicrobials: Synthetic and Natural Compounds summarizes the latest research regarding the possibilities of the most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites. With collected contributions from international subject experts, it focuses primarily on natural produ