The Plasma Proteins V4
The Plasma Proteins V4

Author: Frank Putnam

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 439

ISBN-13: 0323161731

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The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic control of plasma proteins. Advances in the characterization and posttranslational modification of plasma proteins are discussed, along with the structure of a variety of plasma proteins such as serum albumin, glycoproteins, and serum lipoproteins, and immunoglobulins. Comprised of six chapters, this volume begins with a review of progress in plasma proteins, focusing on their three-dimensional structure, characterization, and microheterogeneity as well as genetic polymorphism and chromosomal mapping. The second chapter gives a comprehensive summary of the structure of nearly 100 proteins, from serum albumin and glycoproteins to serum lipoproteins, thyroxine-binding proteins, and immunoglobulins. The reader is then introduced to human plasma proteins of unknown function, together with high-resolution two-dimensional electrophoretic mapping. The remaining chapters explore developments in the structural study of carbon hydrates; synthesis, structure, and function of the oligosaccharides of plasma glycoproteins; and the evolution of the vertebrate plasma proteins. This monograph will be of interest to molecular biologists and biochemists.

The Plasma Proteins
The Plasma Proteins

Author: Frank W Putnam

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 498

ISBN-13: 032313808X

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The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume I is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases. Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes. This monograph will be of interest to molecular biologists and biochemists.

Human Blood Plasma Proteins
Human Blood Plasma Proteins

Author: Johann Schaller

Publisher: John Wiley & Sons

Published: 2008-05-23

Total Pages: 538

ISBN-13: 9780470724361

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Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the complement system the immune system enzymes inhibitors lipoproteins hormones cytokines and growth factors transport and storage The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure. Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.

Production of Plasma Proteins for Therapeutic Use
Production of Plasma Proteins for Therapeutic Use

Author: Joseph Bertolini

Publisher: John Wiley & Sons

Published: 2012-12-26

Total Pages: 518

ISBN-13: 0470924314

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Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.

Iodine Labeled Plasma Proteins
Iodine Labeled Plasma Proteins

Author: Erwin Regoeczi

Publisher: CRC Press

Published: 2019-07-17

Total Pages: 234

ISBN-13: 1000694143

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First Published in 1984, this book offers comprehensive insight into iodine labelled proteins in the blood. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of hematology and other practitioners in their respective fields.

Methods of Enzymatic analysis V4
Methods of Enzymatic analysis V4

Author: Hans-UIrich Bergmeyer

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 761

ISBN-13: 0323161324

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Methods of Enzymatic Analysis, Volume 4 reviews developments in the use of enzymes as tools in analytical biochemistry, including advances in assay techniques. It discusses the principles and methods for the elucidation of structures of enzymes, such as peptides, proteins, amino acids, fatty acid metabolites, lipids, steroids, nucleic acids, purines, pyrimidines, nucleosides, and coenzymes. It also considers the isolation and characterization of active centers in enzymes. This volume is divided into four parts, each discussing a group of enzymes and their determination. Part I focuses on proteins, peptides, and amino acids including amines and amides. Part II is concerned with fatty acid metabolites, lipids, and steroids ranging from polyunsaturated fatty acids and lecithin to choline, acetylcholine, triglycerides, glycerol, acetoacetate, triacetate, fumarylacetoacetate, 20-ketosteroids, prostaglandins, bile acids, and cholesterol. Part III discusses nucleic acids, purines, pyrimidines, nucleosides, coenzymes, and related compounds, whereas Part IV looks at other substrates and effectors such as inorganic phosphate. The book concludes with a chapter on metabolites and their concentrations in animal tissues. Biochemists as well as students and researchers working in the field of analytical biochemistry will find this book highly informative.

Textbook of Human Physiology for Dental Students
Textbook of Human Physiology for Dental Students

Author: Khurana

Publisher: Elsevier India

Published: 2009-11-20

Total Pages: 798

ISBN-13: 9788131205921

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The book fully covers the syllabus prescribed by Dental Council of India and presents a thorough exposition of physiology for undergraduate students. The exposition is systematically divided into eleven sections. Each section begins with a brief overview highlighting the topics covered. The subject is then explained in a graded manner with a large number of diagrams, flowcharts and tables to facilitate an easy understanding. About the Author : - Dr.(Mrs.) Indu Khurana, Associate Professor, Department of Physiology, Postgraduate Institute of Medical Sciences, Rohtak, India. She has a rich experience of more than 25 years of teaching and research. She has to her credit the discovery of a new reflex 'the oculodepressor reflex (ODR)' and three distinct patterns of oculorespiratory reflex (ORR), (British Journal of Ophthalmology, 1997). On account of her contribution to the field, her biographical profile was included in the Marqui's 'Who's Who in Science and Engineering'.