Ageless
Ageless

Author: Andrew Steele

Publisher: Anchor

Published: 2021-03-23

Total Pages: 353

ISBN-13: 0385544936

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“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

Age Later
Age Later

Author: Nir Barzilai, M.D.

Publisher: St. Martin's Press

Published: 2020-06-16

Total Pages: 320

ISBN-13: 1250230861

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How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties? Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s. One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline. In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon—like many other diseases and misfortunes—that can be targeted, improved, and even cured.

Age Proof
Age Proof

Author: Professor Rose Anne Kenny

Publisher: Kings Road Publishing

Published: 2022-01-20

Total Pages: 215

ISBN-13: 1788705076

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___ ***SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE 2022*** Did you know that we can lead longer and healthier lives by making simple changes right now? Professor Rose Anne Kenny has 35 years of experience at the forefront of ageing medicine. In Age Proof, she draws on her own pioneering research and the latest evidence to demystify why we age and shows us that 80% of our ageing biology is within our control: we can not only live longer lives but become happier and healthier deep into our later years. Effortlessly distilling scientific theory into practical advice that we can apply to our everyday lives, Professor Kenny examines the impact that food, genetics, friendships, purpose, sex, exercise and laughter have on how our cells age. This illuminating book will show you the steps you can take to stay younger for longer - and will prove that you really are just as young as you feel.

Biology of Aging
Biology of Aging

Author: Robert Arking

Publisher: Oxford University Press

Published: 2006-02-02

Total Pages: 619

ISBN-13: 0195167392

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Robert Arking's Biology of Aging is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. The mass of data related to aging is summarized into fifteen focused chapters, each dealing with some particular aspect of the problem. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging.

The Life Extension Revolution
The Life Extension Revolution

Author: Philip Lee Miller, M.D.

Publisher: Bantam

Published: 2007-12-18

Total Pages: 416

ISBN-13: 0307418510

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For the first time the lay public can benefit from the anti-aging secrets discovered by the Life Extension Foundation, the world’s largest, most respected organization dedicated to anti-aging research. Working with the Life Extension Foundation, renowned anti-aging physician Philip Lee Miller shows you how to retain your physical health and vigor, mental clarity, and youthful appearance–for life. This groundbreaking book translates cutting-edge anti-aging advances into a practical, easy-to-use program that will maximize your chances of living not only a long life–but a healthy, vibrant life. Drawing on his own clinical experience as well as the latest research from the Life Extension Foundation, Dr. Miller demystifies the aging process and provides you with: •Detailed strategies integrating the most advanced mainstream therapies with nutrients, hormones, and holistic approaches from around the world •A comprehensive plan to protect yourself from cancer, heart disease, arthritis, and Alzheimer’s disease at the cellular level by controlling inflammation and oxidation–two degenerative processes that cause us to age prematurely •A guide to individualizing this lifesaving program, including the Longevity Diet for maximum vitality and effortless weight loss and a unique supplement regimen–plus how to use medical tests to monitor your progress •An inspiring vision of the future of life extension science and what your future will be like without disease, premature death and aging–with novel strategies to help you get there This far-reaching anti-aging program will change your life forever. Like many of Dr. Miller’s patients, your physical and mental health will actually soar as you age chronologically. Your new longer, healthier life begins now as you embark on The Life Extension Revolution.

Defy Aging
Defy Aging

Author: Beth Bennett

Publisher: Rowman & Littlefield

Published: 2021-10-15

Total Pages: 303

ISBN-13: 153815515X

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Shows why and how the body deteriorates as life goes on and offers an easy-read overview of new solutions coming out of current studies of aging. Wrinkles and gray hairs and misplaced keys—the obvious signs of getting older. Surprisingly, all of the miniscule events in our cells and organs that are responsible for aging begin their deterioration in our third decade. This book explains what is going on inside cells and organs that result in the outward appearances of aging. Readers will discover what causes skin to sag, hair to turn gray, blood vessels to stiffen, and other, mostly unwelcome events. Finally, and probably most importantly, the reader will be introduced to what can be done to stop or reverse this process.Beth Bennett provides an easy-to-read introduction to the science of aging: why and how the body deteriorates. She uses real world analogies to explain the chemical and cellular processes taking place in the body, along with newly-discovered solutions emerging from basic research labs. Bennett explores the effects of aging in body systems that are important to all of us as we age: skin, muscle, bone, heart, and brain. In each of these body components, Bennett connects novel, science-based interventions with lifestyle modifications that improve and extend health, as opposed to simply lengthening life.

Cracking the Aging Code
Cracking the Aging Code

Author: Josh Mitteldorf

Publisher: Macmillan

Published: 2016-06-14

Total Pages: 337

ISBN-13: 1250061709

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"Theoretical biologist Josh Mitteldorf and ... ecological philosopher Dorion Sagan [posit] that evolution and aging are even more complex and breathtaking than we originally thought. Using ... multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that 'just happens, ' nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction"--

Ending Aging
Ending Aging

Author: Aubrey de Grey

Publisher: Macmillan + ORM

Published: 2007-09-04

Total Pages: 452

ISBN-13: 1429931833

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MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Handbook of the Biology of Aging
Handbook of the Biology of Aging

Author: Nicolas Musi

Publisher: Academic Press

Published: 2015-08-20

Total Pages: 576

ISBN-13: 0124116205

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Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of 'big data' approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. - Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition - Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline - Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline - Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering - New chapters on genetics, evolutionary biology, bone aging, and epigenetic control - Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions

Lifespan
Lifespan

Author: David A. Sinclair

Publisher: Atria Books

Published: 2019-09-10

Total Pages: 432

ISBN-13: 1501191977

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A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.