It is said that the musk deer searches all its life for the scent that emanates from it. Similarly, we humans look everywhere for peace and happiness but fail to look within ourselves. Through The Musk Syndrome, Ruzbeh N. Bharucha, one of the best known spiritual writers of our times, makes this very simple but profound point. In his anecdotal style, often taking instances from his own life, Ruzbeh demonstrates the strength of our thoughts and actions; our beliefs and practices; and the power of the mind and spirit that we often fail to understand. His approach is not of a Master but of a friend gently nudging you to understand what might be going wrong in your current attitude to life and the people around you. The Musk Syndrome encapsulates the wisdom of life.
The life that inspired the major motion picture The Aviator, starring Leonardo DiCaprio and directed by Martin Scorsese. Howard Hughes has always fascinated the public with his mixture of secrecy, dashing lifestyle, and reclusiveness. This is the book that breaks through the image to get at the man. Originally published under the title Empire: The Life, Legend, and Madness of Howard Hughes.
This updated and expanded new edition of a successful book describes genetic diagnostic entities of neuromuscular disorders. Neuromuscular syndromes are presented clinically either as a case study or as an overview from the literature, accompanied by text presenting molecular defects, and differential diagnosis. This collection of neuromuscular disorders features the differential clinical phenotypes related to each genotype and are representative of the whole spectrum of a genetic muscle disorder, helping the clinician and neuromuscular physician to make a diagnosis. Key points for each genetic disease are identified to suggest treatment, when available, or the main clinical exams useful in follow-up of patients. Genetic Neuromuscular Disorders: A Case-Based Approach is aimed at neuromuscular physicians and neurology residents.
An International Bestseller, the Story behind Henry Markram’s Breakthrough Theory about Autism, and How a Family’s Unconditional Love Led to a Scientific Paradigm Shift Henry Markram is the Elon Musk of neuroscience, the man behind the billion-dollar Blue Brain Project to build a supercomputer model of the brain. He has set the goal of decoding all disturbances of the mind within a generation. This quest is personal for him. The driving force behind his grand ambition has been his son Kai, who has autism. Raising Kai made Henry Markram question all that he thought he knew about neuroscience, and then inspired his groundbreaking research that would upend the conventional wisdom about autism, expressed in his now-famous theory of Intense World Syndrome. When Kai was first diagnosed, his father consulted studies and experts. He knew as much about the human brain as almost anyone but still felt as helpless as any parent confronted with this condition in his child. What’s more, the scientific consensus that autism was a deficit of empathy didn’t mesh with Markram’s experience of his son. He became convinced that the disorder, which has seen a 657 percent increase in diagnoses over the past decade, was fundamentally misunderstood. Bringing his world-class research to bear on the problem, he devised a radical new theory of the disorder: People like Kai don’t feel too little; they feel too much. Their senses are too delicate for this world.
Comprehensive, thoroughly updated, and expanded, Neuromuscular Disorders in Clinical Practice, Second Edition encompasses all disorders of the peripheral nervous system, covering all aspects of neuromuscular diseases from diagnosis to treatment. Mirroring the first book, this two-volume edition is divided into two parts. Part one discusses the approach to neuromuscular disorders, covering principles and basics, neuromuscular investigations, and assessment and treatment of neurological disorders. Part two then addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies, and miscellaneous neuromuscular disorders and syndromes. Neuromuscular Disorders in Clinical Practice, Second Edition is intended to serve as a comprehensive text for both novice and experienced practitioners. General neurologists as well as specialists in neuromuscular medicine and trainees in neuromuscular medicine, clinical neurophysiology and electromyography should find this book inclusive, comprehensive, practical and highly clinically focused. Additionally, specialists in physical medicine and rehabilitation, rheumatology, neurosurgery, and orthopedics will find the book of great value in their practice.
Since publication of the Third Edition in 1998, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This Fourth Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels.New to This Edition:* Tissue-specific interventions to arrest or "cure" autoimmune disease* Bone marrow eradication and replacement* Both basic science and clinical medicine is covered* Boxed points to emphasize key features of each chapter
This issue of Neurologic Clinics, edited by Dr. Mazen M. Dimachkie and Dr. Richard J. Barohn, focuses on Neuromuscular Junction Disorders. Topics include--but are not limited to--History of myasthenia gravis and neuromuscular junction disorders; Practical immunology of the neuromuscular junction; Practical anatomy of the neuromuscular junction in health and disease; Generalized myasthenia gravis; Ocular myasthenia gravis; Diagnosis of myasthenia gravis; MuSK and myasthenia gravis due to other autoantibodies; Treatment of myasthenia gravis; Evidenced-based approach of thymectomy for myasthenia gravis; Myasthenia gravis and pregnancy; Congenital myasthenic syndromes; Botulism; Lambert-Eaton myasthenic syndrome; and Measuring clinical treatment response in myasthenia gravis.
Drawing from the knowledge and expertise of more than 70 contributing international experts, Diseases and Disorders of the Orbit and Ocular Adnexa thoroughly covers the state of the art in orbital and periocular disease from the perspective of a variety of specialties. Clearly written and profusely illustrated, it covers the clinical presentation, pathophysiology, natural history, and management alternatives of disease processes affecting the orbit, eyelids, lacrimal system, and upper face. With a singular focus on the diagnosis and management of orbital and ocular adnexal disease, this authoritative text gives you the information you need to excel both in practice and on exams in the specialty of ophthalmic plastic and reconstructive surgery. - Offers an in-depth and thorough approach to the pathophysiology of oculoplastics and orbital disease, incorporating the perspectives of numerous specialties – all in one convenient volume. - Uses an easy-to-follow, templated format throughout so you can find what you need quickly. - Covers new information not included in other texts, such as antibody testing in dysthyroid conditions and a rapidly emerging array of targeted immunosuppressive medications for the treatment of inflammatory orbital disease. - Includes hot topics such as the classification and management of orbital inflammatory disease; vascular neoplasms and malformations; periocular dermatology; burn management; facial paralytic disease; and the pathogenesis, evaluation and management of lymphoproliferative disease. - Features more than 1,200 high-quality clinical, imaging, and histological illustrations that provide clear visual examples of orbital disease. - Written by an international team of experts from five continents (across multiple specialties including ophthalmology, dermatology, burn management, plastic surgery, otolaryngology, endocrinology, and pathology) led by Dr. Aaron Fay and Dr. Peter J. Dolman.
: In "Imposter Syndrome: Silencing the Self-Doubt Within the Workplace," author Dr. Flowers explores the pervasive phenomenon of imposter syndrome and its impact on individuals navigating the professional landscape. This insightful book delves into the psychology behind imposter syndrome, unraveling the intricate web of self-doubt that often plagues high-achieving individuals. Drawing on real-life anecdotes, research findings, and practical strategies, the author guides readers through the journey of recognizing, understanding, and ultimately overcoming imposter syndrome. From its origins to its manifestations in various professional settings, the book sheds light on the silent struggle many face in their careers. The narrative is crafted to resonate with a broad audience, including both seasoned professionals and those just embarking on their professional journeys. Through a combination of empathy and empowerment, the author aims to inspire readers to challenge their own negative self-perceptions and embrace their achievements with confidence. "Imposter Syndrome" doesn't just dissect the problem—it offers tangible solutions. Readers will find a toolkit of practical exercises, self-reflection prompts, and actionable advice to help them build resilience, reframe negative thoughts, and develop a healthier relationship with their professional identity. This book serves as a valuable resource for anyone seeking to cultivate a more positive and authentic experience within the workplace. By addressing the internal barriers of imposter syndrome, readers are encouraged to step into their true potential, fostering a culture of self-assurance and collective success.
Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations
