The Morphant

The Morphant

Author: Cornelius Fuel

Publisher: Troubador Publishing Ltd

Published: 2017-09-19

Total Pages: 248

ISBN-13: 1788039998

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Gabriel Grant thinks he’s an ordinary 13-year old Londoner. But one day, something happens that leaves him with extraordinary abilities... Suddenly, there are people who want to use him for his powers. What is Gabriel’s connection with a monastery in the distant Himalayas? Who is the mysterious Searcher, and can he be trusted? Who – or what – is spying on Gabriel? Why have his parents suddenly disappeared? And what does all this have to do with a visiting circus? In an adventure based in the heart of London, and together with his feisty sister Ariel, Gabriel eventually finds the answer to many of his questions. Above all: what it means to be a Morphant. Already attracting 5-star reviews as an e-book, The Morphant is a page-turning coming-of-age adventure set against a backdrop of iconic London landmarks, and exploring a secret underground London world before reaching a thrilling climax inside the Channel Tunnel.


The Zebrafish: Disease Models and Chemical Screens

The Zebrafish: Disease Models and Chemical Screens

Author:

Publisher: Academic Press

Published: 2011-09-09

Total Pages: 591

ISBN-13: 0123813212

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This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. - Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls - This volume concentrates on Disease Models and Chemical Screens


Avian Embryology

Avian Embryology

Author:

Publisher: Academic Press

Published: 2011-09-21

Total Pages: 426

ISBN-13: 0080878792

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This revised edition will continue to serve as the most complete and up-to-date guide to the use of the avian embryo in studies of vertebrate development. It will include new approaches to analysis of the chick genome, gene knock-out studies using RNA interference, morpholinos, and other cutting edge techniques. As with the original edition, emphasis has been placed on providing practical guidance, highlighting potentials and pitfalls of all key cell biological and embryological techniques. *fully revised second edition *organized into basic and advanced Methods *new section on Functional Genomics


International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology

Author: Kwang W. Jeon

Publisher: Academic Press

Published: 2012-10-22

Total Pages: 290

ISBN-13: 0123946433

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International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists


Models of Seizures and Epilepsy

Models of Seizures and Epilepsy

Author: Asla Pitkänen

Publisher: Academic Press

Published: 2017-06-14

Total Pages: 1180

ISBN-13: 012804067X

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Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments


The Liver

The Liver

Author: Irwin M. Arias

Publisher: John Wiley & Sons

Published: 2011-08-24

Total Pages: 2022

ISBN-13: 1119964229

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In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology. Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition’s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure. To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at gastrohep.com. To view these chapters visit - http://www.gastrohep.com/theliver/


Animal Models of Human Birth Defects

Animal Models of Human Birth Defects

Author: Aimin Liu

Publisher: Springer Nature

Published: 2020-04-17

Total Pages: 248

ISBN-13: 9811523894

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This book focuses on the use of animal models to study various human defects. It summarizes our current understanding of a variety of common human birth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms leading to many of these developmental disorders has hindered effective prevention and early intervention strategies. Studies using animal models have provided essential insights into several human birth defects. This book serves as a valuable reference resource for researchers and graduate students who are interested in learning the basic principles as well as the latest advances in the study of the mechanisms of human birth defects.


Calcium Signaling

Calcium Signaling

Author: Md. Shahidul Islam

Publisher: Springer Nature

Published: 2019-10-23

Total Pages: 1103

ISBN-13: 3030124576

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This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.