The Malaria Project
The Malaria Project

Author: Karen M. Masterson

Publisher: Penguin

Published: 2014-10-07

Total Pages: 494

ISBN-13: 0698140133

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A fascinating and shocking historical exposé, The Malaria Project is the story of America's secret mission to combat malaria during World War II—a campaign modeled after a German project which tested experimental drugs on men gone mad from syphilis. American war planners, foreseeing the tactical need for a malaria drug, recreated the German model, then grew it tenfold. Quickly becoming the biggest and most important medical initiative of the war, the project tasked dozens of the country’s top research scientists and university labs to find a treatment to remedy half a million U.S. troops incapacitated by malaria. Spearheading the new U.S. effort was Dr. Lowell T. Coggeshall, the son of a poor Indiana farmer whose persistent drive and curiosity led him to become one of the most innovative thinkers in solving the malaria problem. He recruited private corporations, such as today's Squibb and Eli Lilly, and the nation’s best chemists out of Harvard and Johns Hopkins to make novel compounds that skilled technicians tested on birds. Giants in the field of clinical research, including the future NIH director James Shannon, then tested the drugs on mental health patients and convicted criminals—including infamous murderer Nathan Leopold. By 1943, a dozen strains of malaria brought home in the veins of sick soldiers were injected into these human guinea pigs for drug studies. After hundreds of trials and many deaths, they found their “magic bullet,” but not in a U.S. laboratory. America 's best weapon against malaria, still used today, was captured in battle from the Nazis. Called chloroquine, it went on to save more lives than any other drug in history. Karen M. Masterson, a journalist turned malaria researcher, uncovers the complete story behind this dark tale of science, medicine and war. Illuminating, riveting and surprising, The Malaria Project captures the ethical perils of seeking treatments for disease while ignoring the human condition.

The Malaria Project
The Malaria Project

Author: Karen M. Masterson

Publisher: Berkley

Published: 2015-10-06

Total Pages: 0

ISBN-13: 9780451467331

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During the Second World War American war planners conducted one of the most important medical initiatives of the century and attempted to find a cure for malaria. The project tasked dozens of the country's top research scientists and university labs, and new drugs were tested on mental health patients and convicted criminals. The trials caused hundreds of deaths. The Malaria Project is the complete story behind this dark tale of science, medicine and war.

Healing the Land and the Nation
Healing the Land and the Nation

Author: Sandra M. Sufian

Publisher: University of Chicago Press

Published: 2008-11-15

Total Pages: 406

ISBN-13: 0226779386

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A novel inquiry into the sociopolitical dimensions of public medicine, Healing the Land and the Nation traces the relationships between disease, hygiene, politics, geography, and nationalism in British Mandatory Palestine between the world wars. Taking up the case of malaria control in Jewish-held lands, Sandra Sufian illustrates how efforts to thwart the disease were intimately tied to the project of Zionist nation-building, especially the movement’s efforts to repurpose and improve its lands. The project of eradicating malaria also took on a metaphorical dimension—erasing anti-Semitic stereotypes of the “parasitic” Diaspora Jew and creating strong, healthy Jews in Palestine. Sufian shows that, in reclaiming the land and the health of its people in Palestine, Zionists expressed key ideological and political elements of their nation-building project. Taking its title from a Jewish public health mantra, Healing the Land and the Nation situates antimalarial medicine and politics within larger colonial histories. By analyzing the science alongside the politics of Jewish settlement, Sufian addresses contested questions of social organization and the effects of land reclamation upon the indigenous Palestinian population in a decidedly innovative way. The book will be of great interest to scholars of the Middle East, Jewish studies, and environmental history, as well as to those studying colonialism, nationalism, and public health and medicine.

Saving Lives, Buying Time
Saving Lives, Buying Time

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2004-09-09

Total Pages: 384

ISBN-13: 0309165938

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For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

Malaria
Malaria

Author: Margaret Humphreys

Publisher: JHU Press

Published: 2001-10-23

Total Pages: 209

ISBN-13: 0801866375

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This is the story of a war against a disease that we can never win but must continue to fight. In Malaria: Poverty, Race, and Public Health in the United States, Margaret Humphreys presents the first book-length account of the parasitic, insect-borne disease that has infected millions and influenced settlement patterns, economic development, and the quality of life at every level of American society, especially in the south. Humphreys approaches malaria from three perspectives: the parasite's biological history, the medical response to it, and the patient's experience of the disease. It addresses numerous questions including how the parasite thrives and eventually becomes vulnerable, how professionals came to know about the parasite and learned how to fight them, and how people view the disease and came to the point where they could understand and support the struggle against it. In addition Malaria: Poverty, Race, and Public Health in the United States argues that malaria control was central to the evolution of local and federal intervention in public health, and demonstrates the complex interaction between poverty, race, and geography in determining the fate of malaria.

Malaria
Malaria

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1991-02-01

Total Pages: 312

ISBN-13: 9780309045278

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Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

War and Disease
War and Disease

Author: Leo Barney Slater

Publisher: Rutgers University Press

Published: 2009

Total Pages: 266

ISBN-13: 0813544386

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Fighting around the globe, American soldiers were at high risk for contracting malaria, yet quinine - a natural cure - became hard to acquire. This historical study shows the roots and branches of an enormous drug development project during World War II.

Malaria Control During Mass Population Movements and Natural Disasters
Malaria Control During Mass Population Movements and Natural Disasters

Author: Program on Forced Migration and Health at the Mailman School of Public Health of Columbia University

Publisher: National Academies Press

Published: 2003-01-16

Total Pages: 181

ISBN-13: 0309086159

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Admittedly, the world and the nature of forced migration have changed a great deal over the last two decades. The relevance of data accumulated during that time period can now be called into question. The roundtable and the Program on Forced Migration at the Mailman School of Public Health of Columbia University have commissioned a series of epidemiological reviews on priority public health problems for forced migrants that will update the state of knowledge. Malaria Control During Mass Population Movements and Natural Disasters- the first in the series, provides a basic overview of the state of knowledge of epidemiology of malaria and public health interventions and practices for controlling the disease in situations involving forced migration and conflict.

Advances in Malaria Research
Advances in Malaria Research

Author: Deepak Gaur

Publisher: John Wiley & Sons

Published: 2016-12-27

Total Pages: 611

ISBN-13: 1118493796

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Thoroughly reviews our current understanding of malarial biology Explores the subject with insights from post-genomic technologies Looks broadly at the disease, vectors of infection, and treatment and prevention strategies A timely publication with chapters written by global researchers leaders