Ross Donaldson is one of just a few who have ventured into dark territory of a country ravaged by war to study one of the world's most deadly diseases. As an untried medical student studying the intersection of global health and communicable disease, Donaldson soon found himself in dangerous Sierra Leone, on the border of war-struck Liberia, where he struggled to control the spread of Lassa Fever. The words, "you know Lassa can kill you, don't you?" haunted him each day. With the country in complete upheaval and working conditions suffering, he is forced to make life-and-death decisions alone as a never-ending onslaught of contagious patients flood the hospital. Soon however, he is not only fighting for others but himself when he becomes afflicted with a life threatening disease. The Lassa Ward is more than just an adventure story about the making of a physician; it is a portrait of the Sierra Leone people and the human struggle of those risking their daily comforts and lives to aid them.
Straight out of today’s hospitals and labs–and tomorrow’s headlines–comes a frightening, scalpel-sharp thriller from medical insider Joshua Spanogle. In an astounding debut, Spanogle takes us on an all-too-real race against time…as a young doctor enters the dark side of scientific research, desperate to stop a terrifying epidemic before it is too late…. In Baltimore’s St. Raphael’s Hospital, three newly admitted patients are among society’s most helpless citizens: female residents of Baltimore’s group homes for the mentally impaired, their bodies racked by a virus the likes of which no one at St. Raphael’s has ever seen. Dr. Nathaniel McCormick is one of the first on the scene. A young investigator from the Centers for Disease Control, Nate is paid to explore the bizarre, the exotic, and the baffling–from superviruses to bioterrorism. But as soon as Nate begins to investigate the lives and habits of the victims, he knows something is terribly wrong. Using all his skills as a medical detective, Nate soon zeroes in on the “vector”–the one person who had sexual contact with the first victims. And when that suspect is found murdered, Nate fears that the disease he’s chasing may not be an act of nature, but of man. With his brash style angering his superiors and fellow investigators alike, Nate turns to an old colleague and former lover, Dr. Brooke Michaels, for help. Together the two investigators follow a twisting trail of clues to a discovery that is at once groundbreaking and unspeakable. And as a circle of treachery tightens around him, Nate is about to confront the most chilling revelation of all–and a past Nate himself has been trying to escape. At once a taut medical thriller and a riveting psychological portrait of a young doctor on the edge, Isolation Ward is a tale of runaway tension–with a brilliant “what-if” premise that is harrowing…heartbreaking…and impossible to wrench from your imagination.
A Choice Outstanding Academic Title of the Year ÒA critical, poignant postmortem of the epidemic.Ó ÑWashington Post ÒForceful and instructive...Sabeti and Salahi uncover competition, sabotage, fear, blame, and disorganization bordering on chaos, features that are seen in just about any lethal epidemic.Ó ÑPaul Farmer, cofounder of Partners in Health ÒThe central theme of the book...is that common threads of dysfunction run through responses to epidemics...The power of Outbreak Culture is its universality.Ó ÑNature ÒSabeti and Salahi present a wealth of evidence supporting the imperative that outbreak response must operate in a coordinated, real-time manner.Ó ÑScience As we saw with the Ebola outbreakÑand the disastrous early handling of the COVID-19 coronavirus pandemicÑa lack of preparedness, delays, and system-wide problems with the distribution of critical medical supplies can have deadly consequences. Yet after every outbreak, the systems put in place to coordinate emergency responses are generally dismantled. One of AmericaÕs top biomedical researchers, Dr. Pardis Sabeti, and her Pulitzer PrizeÐwinning collaborator, Lara Salahi, argue that these problems are built into the ecosystem of our emergency responses. With an understanding of the path of disease and insight into political psychology, they show how secrecy, competition, and poor coordination plague nearly every major public health crisis and reveal how much more could be done to safeguard the well-being of caregivers, patients, and vulnerable communities. A work of fearless integrity and unassailable authority, Outbreak Culture seeks to ensure that we make some urgently needed changes before the next pandemic.
First published in March 2014 under the title "Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers: interim emergency guidance for West Africa".
“Paul Farmer brings his considerable intellect, empathy, and expertise to bear in this powerful and deeply researched account of the Ebola outbreak that struck West Africa in 2014. It is hard to imagine a more timely or important book.” —Bill and Melinda Gates "[The] history is as powerfully conveyed as it is tragic . . . Illuminating . . . Invaluable." —Steven Johnson, The New York Times Book Review In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it? Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand—Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa’s chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not – and the region’s health care woes worsened, with devastating consequences that Farmer traces up to the present. This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.
NEW YORK TIMES BESTSELLER • An urgent wake-up call about the future of emerging viruses and a gripping account of the doctors and scientists fighting to protect us, told through the story of the deadly 2013–2014 Ebola epidemic “Crisis in the Red Zone reads like a thriller. That the story it tells is all true makes it all more terrifying.”—Elizabeth Kolbert, Pulitzer Prize–winning author of The Sixth Extinction From the #1 bestselling author of The Hot Zone, now a National Geographic original miniseries . . . This time, Ebola started with a two-year-old child who likely had contact with a wild creature and whose entire family quickly fell ill and died. The ensuing global drama activated health professionals in North America, Europe, and Africa in a desperate race against time to contain the viral wildfire. By the end—as the virus mutated into its deadliest form, and spread farther and faster than ever before—30,000 people would be infected, and the dead would be spread across eight countries on three continents. In this taut and suspenseful medical drama, Richard Preston deeply chronicles the pandemic, in which we saw for the first time the specter of Ebola jumping continents, crossing the Atlantic, and infecting people in America. Rich in characters and conflict—physical, emotional, and ethical—Crisis in the Red Zone is an immersion in one of the great public health calamities of our time. Preston writes of doctors and nurses in the field putting their own lives on the line, of government bureaucrats and NGO administrators moving, often fitfully, to try to contain the outbreak, and of pharmaceutical companies racing to develop drugs to combat the virus. He also explores the charged ethical dilemma over who should and did receive the rare doses of an experimental treatment when they became available at the peak of the disaster. Crisis in the Red Zone makes clear that the outbreak of 2013–2014 is a harbinger of further, more severe outbreaks, and of emerging viruses heretofore unimagined—in any country, on any continent. In our ever more interconnected world, with roads and towns cut deep into the jungles of equatorial Africa, viruses both familiar and undiscovered are being unleashed into more densely populated areas than ever before. The more we discover about the virosphere, the more we realize its deadly potential. Crisis in the Red Zone is an exquisitely timely book, a stark warning of viral outbreaks to come.
Zoonotic diseases – pathogens transmitted from animals to people – offer particularly challenging problems for global health institutions and actors, given the complex social-ecological dynamics at play. New forms of risk caused by unprecedented global connectivity and rapid social and environmental change demand new approaches. ‘One Health’ highlights the need for collaboration across sectors and disciplines to tackle zoonotic diseases. However, there has been little exploration of how social, political and economic contexts influence efforts to ‘do’ One Health. This book fills this gap by offering a much needed political economy analysis of zoonosis research and policy. Through ethnographic, qualitative and quantitative data, the book draws together a diverse number of case studies. These include chapters exploring global narratives about One Health operationalization and prevailing institutional bottlenecks; the evolution of research networks over time; and the histories and politics behind conflicting disease control approaches. The themes from these chapters are further contextualized and expanded upon through country-specific case studies – from Kenya, Zambia, Nigeria, Ghana and Sierra Leone – exploring the translation of One Health research and policy into the African context. This book is a valuable resource for academic researchers, students and policy practitioners in the areas of global health, agriculture and development.
From 2013 to 2015, over 11,000 people across West Africa lost their lives to the deadliest outbreak of the Ebola virus in history. Crucially, this epidemic marked the first time the virus was able to spread beyond rural areas to major cities, overturning conventional assumptions about its epidemiology. With backgrounds ranging from development to disease control, the contributors to this volume - some of them based in countries affected by the Ebola epidemic - consider the underlying factors that shaped this unprecedented outbreak. While championing the heroic efforts of local communities and aid workers in halting the spread of the disease, the contributors also reveal deep structural problems in both the countries and humanitarian agencies involved, which hampered the efforts to contain the epidemic. Alarmingly, they show that little has been learned from these events, with health provision remaining underfunded and poorly equipped to deal with future outbreaks. Such issues, they argue, reflect the wider challenges we face in tackling epidemic disease in an increasingly interconnected world.
Ebola: Clinical Patterns, Public Health Concerns is a concise description and discussion of the Ebola virus and disease. The intended audience is medical practitioners, including those working in endemic areas as well as health-facility planners and public health practitioners. The book fills an important gap between large texts covering not only Ebola but other hemorrhagic fever viruses and brief pamphlet-style publications on the public health aspects of the infection. In light of the recent large outbreak in West Africa, this book is a part of the developing foundation needed to deal with emerging diseases.
