Author Omar Muhammad is formerly Omar Saunders of the Roscetti 4. Omar takes you deep into the truth and facts of the brutal rape and murder of medical student Lori Roscetti and the wrongful conviction of his co-defendants as well as himself. Omar outlines the levels of the conspiracy to frame young innocent kids based upon an FBI profile because investigators could not solve the case. The Author explains in vivid detail once and for all what happened to Lori Roscetti. Kids with marginal backgrounds chosen by corrupt officials to be the scapegoats the sacrifice for one of Chicago's most horrific historic tragedies. A powerful and a gripping memoir.
The rise in popularity of dermoscopy has meant that more and more practitioners need a ready reference to consult in a clinical setting where larger atlases are less practical. The Handbook of Dermoscopy features a wealth of photographs, checklists, and algorithms to assist in spot diagnoses. Coverage includes melanocytic lesions, seborrheic kerato
New technological approaches in dermatologic diagnostics, such as surface microscopy and dermoscopy, are continuously advancing. Anatomical structures can be viewed like never before. Through these new techniques the necessity of a new terminology and a new set of dermoscopic criteria has come up. So far, many different and sometimes confusing terms have been used in designating these microscopic features. However, the daily challenge physicians face when evaluating skin lesions acquires immediate access to the current dermoscopic nomenclature and definition. This unique guide provides a comprehensive, current, and accurate A-Z encyclopaedia to clarify the meaning of surface microscopic and dermoscopic terminology including a broad range of both melanocytic and non-melanocytic skin lesions. It will support dermatologists, histopathologists and all other physicians in charge of a biopsy and excision decision.
Twenty years ago, the enzyme superoxide dismutase which uses the superoxide radical anion as its specific substrate was reported. With this discovery was born a new scientific field, in which oxygen, necessary for aerobi c 1 ife on thi s planet, had to be cons i dered also in terms of its toxicity and stresses. This stimulated the search for knowledge of active oxygen species in biology and medicine. Superoxide and other reactive oxygen species are now implicated in many disease processes. Major advances have been achieved during these past years with respect to free radical generation and mechanisms of free radical action in causing tissue injury. In parallel, the possibil ity of influencing free radical related disease processes by antioxidant treatment was studied in various in vitro and in vivo systems. This was the unique theme of a conference organized in Paris by the Society for Free Radical Research (December 9-10, 1988) which brought together experts from basic sciences and clinicians in order to evaluate the current status of antioxidant therapy. The conference emphasized fundamental processes in antioxidant action. Among the major topics were superoxide dismutase (SOD) and low molecular weight substances with such activity, called SOD mimics. Other antioxidant enzymes were also considered. Antioxidant vitamins, in particular vitamins E and C, other naturally occurri ng antioxidants and vari ous synthet i c antioxidants were included in the presentations as there is now a rapidly developing series of compounds with potentially interesting clinical applications.
This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates, and therapeutic strategies to overcome refractory epilepsy. The last section illustrates the potential benefits that network pharmacology and rational drug repurposing could bring to the antiepileptic drug discovery community. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of detailed description and implementation advice to ensure results in the laboratory. Authoritative and practical, Antiepileptic Drug Discovery: Novel Approaches aims to provide medicinal chemists, pharmacologists, and other researchers with the tools need to further explore the study of pharmacoresistant epilepsy and the discovery of new antiepileptic drugs.
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Since the beginning of the Republic, the President's chief advisor in the interpretation of the Constitution has been the Attorney General. The opinions of the Attorneys General on constitutional topics are official statements of the executive branch's views, and in many circumstances where a constitutional question cannot come before a court, their opinions provide the final answer. This book offers the most important constitutional opinions of the Attorneys General and the Department of Justice from Edmund Randolph (President Washington's first Attorney General) to Janet Reno. Powell's commentary provides biographical and historical context to enhance the reader's appreciation of the opinions, which cover such topics as the separation of powers, the authority of Congress and the President over matters of war and peace, the nature of citizenship, and the executive's responsibilities with respect to statutes that the President believes unconstitutional. The opinions are presented in full text and with original pagination, making The Constitution and the Attorneys General a fully independent research tool. A variety of indices and tables give the reader full access to the executive branch's two-century-long tradition of construing and applying the Constitution. "A superb and invaluable source book for graduate students in political science, historians, and legal scholars." -- CHOICE Magazine
