The Hunt for FOXP5

The Hunt for FOXP5

Author: Wallace Kaufman

Publisher: Springer

Published: 2016-05-03

Total Pages: 256

ISBN-13: 3319289616

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Genetics professor Michelle Murphy loses her husband under mysterious circumstances and without warning, while their brilliant eight year old daughter Avalon, adopted in Kazakhstan, stubbornly believes she is a mutant. As if this were not enough she soon finds herself thrown into the middle of a quickly thickening plot, where the legacy of Genghis Khan meets the hunt for FOXP5, a genetic transcription factor that could herald the dawn of new human species. Initially caught helplessly between well-meaning fellow scientists, the government and more sinister agents, Michelle, with the help of a host of unlikely heroes, eventually takes control and finds the courage to confront the decision of whether to save human lives or humanity. The scientific and technical aspects underlying the plot - in particular aspects of FOX proteins, genetic mutations, viruses and cancer as well as the relation between intelligence and cortical complexity - are introduced and discussed by the authors in an extensive non-technical appendix.


Protocells

Protocells

Author: Steen Rasmussen

Publisher: MIT Press

Published: 2022-06-07

Total Pages: 723

ISBN-13: 0262545888

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The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory. Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory. These minimal versions of cells, known as protocells, are entities with lifelike properties created from nonliving materials, and the book provides in-depth investigations of processes at the interface between nonliving and living matter. Chapters by experts in the field put this state-of-the-art research in the context of theory, laboratory work, and computer simulations on the components and properties of protocells. The book also provides perspectives on research in related areas and such broader societal issues as commercial applications and ethical considerations. The book covers all major scientific approaches to creating minimal life, both in the laboratory and in simulation. It emphasizes the bottom-up view of physicists, chemists, and material scientists but also includes the molecular biologists' top-down approach and the origin-of-life perspective. The capacity to engineer living technology could have an enormous socioeconomic impact and could bring both good and ill. Protocells promises to be the essential reference for research on bottom-up assembly of life and living technology for years to come. It is written to be both resource and inspiration for scientists working in this exciting and important field and a definitive text for the interested layman.


First Life

First Life

Author: David Deamer

Publisher: Univ of California Press

Published: 2011-06

Total Pages: 288

ISBN-13: 0520258320

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All life starts as stardust and all life requires packaging for molecules, proteins, DNA, and other crucial bits. Introducing astrobiology, this book presents a provocative hypothesis for the environmental conditions and raw materials needed for life to begin and evolve on earth.


Membrane Permeability: 100 Years Since Ernest Overton

Membrane Permeability: 100 Years Since Ernest Overton

Author:

Publisher: Academic Press

Published: 1999-05-21

Total Pages: 443

ISBN-13: 0080585191

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Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. - Provides an historical perspective of Overton's contributions to the theory of narcosis - Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion


Coming Out Of The Woods

Coming Out Of The Woods

Author: Wallace Kaufman

Publisher: Da Capo Press, Incorporated

Published: 2000-05-31

Total Pages: 358

ISBN-13:

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A beautifully written, unsentimental account that challenges our Thoreauvian romance with nature and offers the conclusion that in civilization is the preservation of the wildness that we cherish.


Origin of Life

Origin of Life

Author: David W. Deamer

Publisher: Oxford University Press

Published: 2020-08-01

Total Pages: 160

ISBN-13: 0190099011

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It seems likely that scientists will someday discover how life can emerge on habitable planets like the early Earth and Mars. In Origin of Life: What Everyone Needs to Know®, David W. Deamer has written a comprehensive guide to the origin of life that is organized in three sections. The first section addresses questions such as: Where do the atoms of life come from? How old is Earth? What was the Earth like before life began? Where does water come from? After each question is answered, there is a follow-up: How do we know? This expands the horizon of the book, explaining how scientists reach conclusions and why we can trust these answers. The second section describes how certain organic molecules can spontaneously assemble into populations of protocells that can undergo selection and evolve toward primitive living systems. Here Deamer proposes a truly novel concept that life did not begin in the ocean but instead in fresh water hot springs on volcanic land masses resembling Hawaii today. True knowledge is not just what we know, but equally important is what we don't yet know. In the third section Deamer lists the outstanding questions that must be addressed before we can finally answer a fundamental question of biology: How can life begin?


The Beaches Are Moving

The Beaches Are Moving

Author: Wallace Kaufman

Publisher: Duke University Press

Published: 1984-01-13

Total Pages: 354

ISBN-13: 0822382946

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Our beaches are eroding, sinking, washing out right under our houses, hotels, bridges; vacation dreamlands become nightmare scenes of futile revetments, fills, groins, what have you—all thrown up in a frantic defense against the natural system. The romantic desire to live on the seashore is in doomed conflict with an age-old pattern of beach migration. Yet it need not be so. Conservationist Wallace Kaufman teams up with marine geologist Orrin H. Pilkey Jr., in an evaluation of America's beaches from coast to coast, giving sound advice on how to judge a safe beach development from a dangerous one and how to live at the shore sensibly and safely.


The Origins of Life

The Origins of Life

Author: David W. Deamer

Publisher:

Published: 2010

Total Pages: 0

ISBN-13: 9781936113040

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Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems. Also covered in the book are new synthetic approaches for fabricating cellular systems, the potentially extraterrestrial origin of life's building blocks, and the possibility that life once existed on Mars. Comprising five sections Setting the Stage, Components of First Life, Primitive Systems, First Polymers, and Transition to a Microbial World it is a vital reference for all scientists interested in the origin of life on Earth and the likelihood that it has arisen on other planets


The Bird who Cleans the World

The Bird who Cleans the World

Author: Victor Montejo

Publisher:

Published: 1991

Total Pages: 136

ISBN-13:

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These Mayan fables and animal stories were collected and transcribed by the author from Jakaltek-Maya language, one of the 21 Mayan languages that are still spoken in Guatemala. The stories are firmly rooted in the world of nature, demonstrating and insisting on honesty, understanding and respect among people and their cultures.


The Divine Madness of Philip K. Dick

The Divine Madness of Philip K. Dick

Author: Kyle Arnold

Publisher: Oxford University Press

Published: 2016

Total Pages: 249

ISBN-13: 0199743258

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The Divine Madness of Philip K. Dick, written by a psychologist, investigates the inner world of the science fiction writer Philip K. Dick. In 1974, Dick was beset by religious visions, and warned police he was an android. The book explores whether Dick's experience was a spiritual awakening or caused by mental illness.