The History of Oncology

The History of Oncology

Author: D. J. Th. Wagener

Publisher: Bohn Stafleu van Loghum

Published: 2009-07-13

Total Pages: 318

ISBN-13: 9789031361434

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‘The story of oncology is not only fascinating but also contains many accounts of dead ends, chance discoveries, illusions, mistakes and disappointments alongside the few successes.’These words are taken from the introduction to this book. The author, professor emeritus of Medical Oncology, reviews all aspects of the problem of cancer from a historical perspective, from the oldest existing records to the latest scientific and medical advances. It will interest the many people engaged in the treatment of cancer to read how the current therapeutic methods came about, and the book may also provide inspiration for cancer researchers, and for all those directly or indirectly involved with cancer. The layman looking for background information on a particular treatment may find it useful too. The various chapters can be read independently. A glossary and a few explanatory diagrams augment the text.This book grew out of an invitation the author received to lecture on the history of oncology. During his background reading, he discovered that there was no single volume dealing with the entire history of the subject. Fortunately, however, a great deal of information could be found here and there in the literature. As he read, he was struck by the fascinating stories behind many discoveries, and felt impelled to put them together in a single comprehensive account. The results of his labors are presented in this remarkable volume.The author, Prof. D.J.Th. (Theo) Wagener, was head of the department of Medical Oncology at the Radboud University Nijmegen Medical Centre in the Netherlands from 1982 to 2001, chairman of the Educational Committee of the European Society of Medical Oncology (ESMO), a member of the Educational Committee of the American Society of Clinical Oncology (ASCO) and a member of various international scientific working groups, mainly of the European Organization for Research and Treatment of Cancer (EORTC).


Holland-Frei Cancer Medicine

Holland-Frei Cancer Medicine

Author: Robert C. Bast, Jr.

Publisher: John Wiley & Sons

Published: 2017-03-10

Total Pages: 2004

ISBN-13: 111900084X

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Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates


The Emperor of All Maladies

The Emperor of All Maladies

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

Published: 2011-08-09

Total Pages: 624

ISBN-13: 1439170916

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Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.


The Secret History of the War on Cancer

The Secret History of the War on Cancer

Author: Devra Davis

Publisher: PublicAffairs

Published: 2009-02-24

Total Pages: 562

ISBN-13: 0465015689

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From the National Book Award finalist and author of "When Smoke Ran Like Water" comes this searing, haunting, and deeply personal account of how a major public health effort was diverted and distorted for private gain.


Oxford Case Histories in Oncology

Oxford Case Histories in Oncology

Author: Thankamma Ajithkumar

Publisher:

Published: 2014-03

Total Pages: 328

ISBN-13: 0199664536

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Oxford Case Histories in Oncology contains 30 well-structured cases from clinical practice, giving a comprehensive coverage of the diagnostic and management dilemmas in oncology. The cases cover a wide spectrum of oncology including rare presentations and clinical problems of common cancers. Each case comprises a brief clinical history with relevant clinical examination findings. Questions are based on clinical investigations and aspects of management. Detailed answers are based on the best available evidence from the latest research, systematic reviews, meta-analysis and guidelines from national and international academic bodies. The text is complimented by over 50 illustrations, including radiographic images and radiotherapy treatment plans. The format of this book is thought provoking, and it helps to improve critical thinking and interpretative skills. It is a perfect self-assessment tool for oncology and palliative medicine trainees and consultants, and will be useful for those preparing for exit examinations in oncology. It will also be of interest to non-specialist readers who wish to improve their skills in the diagnosis and management of a broad range of cancers.


Oxford Textbook of Oncology

Oxford Textbook of Oncology

Author: David J. Kerr

Publisher: Oxford University Press

Published: 2016-01-28

Total Pages: 2837

ISBN-13: 0191065110

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Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.


Basics of Oncology

Basics of Oncology

Author: Frederick O Stephens

Publisher: Springer Science & Business Media

Published: 2009-04-29

Total Pages: 377

ISBN-13: 3540929258

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"Basics of Oncology" provides an easily understood and general overview of the basic medical, scientific and clinical aspects of cancer. Causes, pathology, clinical features, diagnostic investigations, treatments and outcomes are all carefully explained and discussed, both for cancers in general and for the common cancers in individual countries. The reader will thereby be provided with an understanding of how and why people develop cancer, how the body reacts to cancer, what can be done to prevent the disease, and how the various cancers are best diagnosed and treated. The book will serve as a sound basis for the more detailed or specific studies that may be needed in different areas of practice and in different countries. It will be invaluable for students of medicine, nurse oncologists, students of medical sciences and other health professionals in all parts of the world.


Surgery

Surgery

Author: Jeffrey Norton

Publisher: Springer Science & Business Media

Published: 2009-04-21

Total Pages: 2419

ISBN-13: 0387681132

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Much anticipated, the Second Edition of Surgery: Basic Science and Clinical Evidence features fully revised and updated information on the evidence-based practice of surgery, including significant new sections on trauma and critical care and the often challenging surgical care of unique populations, including elderly, pediatric, immunocompromised, and obese patients as well as timely new chapters on the pre- and post-operative care of the cardiac surgery patient, intestinal transplantation, surgical infections, the fundamentals of cancer genetics and proteomics. Also new to this edition are discussions of electrosurgical instruments, robotics, imaging modalities, and other emerging technologies influencing the modern practice of surgery. Clinically focused sections in gastrointestinal, vascular, cardiothoracic, transplant, and cancer surgery enable the surgeon to make decisions based upon the most relevant data in modern surgical practice. The text is enhanced by more than 1,000 illustrations and hundreds of the signature evidence-based tables that made the first edition of SURGERY an instant classic.


Philosophy of Cancer

Philosophy of Cancer

Author: Marta Bertolaso

Publisher: Springer

Published: 2016-08-24

Total Pages: 200

ISBN-13: 9402408657

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Since the 1970s, the origin of cancer is being explored from the point of view of the Somatic Mutation Theory (SMT), focusing on genetic mutations and clonal expansion of somatic cells. As cancer research expanded in several directions, the dominant focus on cells remained steady, but the classes of genes and the kinds of extra-genetic factors that were shown to have causal relevance in the onset of cancer multiplied. The wild heterogeneity of cancer-related mutations and phenotypes, along with the increasing complication of models, led to an oscillation between the hectic search of ‘the’ few key factors that cause cancer and the discouragement in face of a seeming ‘endless complexity’. To tame this complexity, cancer research started to avail itself of the tools that were being developed by Systems Biology. At the same time, anti-reductionist voices began claiming that cancer research was stuck in a sterile research paradigm. This alternative discourse even gave birth to an alternative theory: the Tissue Organization Field Theory (TOFT). A deeper philosophical analysis shows limits and possibilities of reductionist and anti-reductionist positions and of their polarization. This book demonstrates that a radical philosophical reflection is necessary to drive cancer research out of its impasses. At the very least, this will be a reflection on the assumptions of different kinds of cancer research, on the implications of what cancer research has been discovering over 40 years and more, on a view of scientific practice that is most able to make sense of the cognitive and social conflicts that are seen in the scientific community (and in its results), and, finally, on the nature of living entities with which we entertain this fascinating epistemological dance that we call scientific research. The proposed Dynamic and Relational View of carcinogenesis is a starting point in all these directions.


Cancer as a Metabolic Disease

Cancer as a Metabolic Disease

Author: Thomas Seyfried

Publisher: John Wiley & Sons

Published: 2012-05-18

Total Pages: 482

ISBN-13: 1118310306

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The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.