Cook-Deegan, a former director of the Biomedical Ethics Advisory Committee of the US Congress and an advisor to the National Center for Human Genome Research, gives a firsthand account of the struggle to launch the Human Genome Project. Using primary documents and interviews, Cook-Deegan explains scientific details, chronicles the origins of the project, covers the conflicts and partnerships between the organizations involved, and examines ethical, legal, and social issues of DNA research. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR
Cook-Deegan, a former director of the Biomedical Ethics Advisory Committee of the US Congress and an advisor to the National Center for Human Genome Research, gives a firsthand account of the struggle to launch the Human Genome Project. Using primary documents and interviews, Cook-Deegan explains scientific details, chronicles the origins of the project, covers the conflicts and partnerships between the organizations involved, and examines ethical, legal, and social issues of DNA research. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR
From C.J. Cherryh, one of science fiction′s greatest writers and a 3-time Hugo Award "Best Novel" winner, comes the exciting and long-awaited follow-up to Hammerfall, the second novel of the Gene Wars, now in mass market. In the second volume of "The Gene Wars," C. J. Cherryh further explores the captivating new universe where two interstellar empires, scarred by nanotechnology weaponry, hover in an uneasy detente. Perched at the edge of the galaxy, tiny Concord Station holds the balance of the universe within its carefully regulated worlds. For, created to carefully monitor the crucial desert planet below, it lies in the tenuous intersection between the territories of Earth and the alien Ondat. Marak Trin Tain has saved a planet′s people from total destruction, when the implacable ondat sent down a hammerfall to destroy the planet and keep its deadly nanoceles from changing life and evolution forever. But the regrowing planet is fragile, and a deadly cataclysm could destroy Marak--and with him, the hope for peace within the universe. Meanwhile, on Concord, an unexpected ship from Earth disrupts the uneasy truces between human and alien, and the consequences could restart the terrible Gene Wars that once destroyed most of humanity.
The Hugo Award–winning author and SFWA Grand Master delivers the first Gene Wars novel and “a brand-new universe with brand-new rules” (The San Diego Union Tribune). In this brilliant novel—possibly Cherryh’s masterwork—the fate of billions has come down to a confrontation between two profoundly alien cultures on a single desert planet. Marak has suffered the madness his entire life. He is a prince and warrior, strong and shrewd and expert in the ways of the desert covering his planet. In the service of his father, he has dedicated his life to overthrowing the Ila, the mysterious eternal dictator of his world. For years he has successfully hidden the visions of a silver tower that plague him, but when his secret is discovered, Marak is betrayed by his own father and forced to march in an endless caravan with the rest of his world’s madmen to the Ila’s city of Oburan. Instead of death, Marak finds in Oburan his destiny, and the promise of life—if he can survive an impossible mission given to him by the strange people in the towers. According to these beings who look like him yet act differently than anyone he has ever known, Marak has a slim chance to save his world’s people from the wrath of Ila’s enemies. But to do so, he must convince them all—warring tribes, villagers, priests, young and old, as well as the Ila herself—to follow him on an epic trek across the burning desert before the hammer of the Ila’s foes falls from the heavens above. “C. J. Cherryh remains at the top of her game.” —Tulsa World
Despite technological advances, an alarming number of people in the world go hungry. Even more chilling is the fact that in the future that number will likely increase. In this book, Kristin Dawkins discusses the international policies that are shaping this future, including those that govern the genetic engineering of plants. Dawkins shows how a diversified gene pool is crucial to food production - and how corporate control of the gene pool threatens our collective security. Behind these issues lies the specter of globalization - transnational corporations freely exploiting the resources and consumers of the world while political power shifts to remote international institutions strictly dedicated to commerce. Dawkins challenges those in power to develop global systems of political discourse in the public interest and shows how each one of us can make a difference.
In 1969, Jon Beckwith and his colleagues succeeded in isolating a gene from the chromosome of a living organism. Announcing this startling achievement at a press conference, Beckwith took the opportunity to issue a public warning about the dangers of genetic engineering. Jon Beckwith's book, the story of a scientific life on the front line, traces one remarkable man's dual commitment to scientific research and social responsibility over the course of a career spanning most of the postwar history of genetics and molecular biology. A thoroughly engrossing memoir that recounts Beckwith's halting steps toward scientific triumphs--among them, the discovery of the genetic element that turns genes on--as well as his emergence as a world-class political activist, Making Genes, Making Waves is also a compelling history of the major controversies in genetics over the last thirty years. Presenting the science in easily understandable terms, Beckwith describes the dramatic changes that transformed biology between the late 1950s and our day, the growth of the radical science movement in the 1970s, and the personalities involved throughout. He brings to light the differing styles of scientists as well as the different ways in which science is presented within the scientific community and to the public at large. Ranging from the travails of Robert Oppenheimer and the atomic bomb to the Human Genome Project and recent "Science Wars," Beckwith's book provides a sweeping view of science and its social context in the latter half of the twentieth century.
The 2nd Edition of Who Owns You, David Koepsell’s widely acclaimed exploration of the philosophical and legal problems of patenting human genes, is updated to reflect the most recent changes to the cultural and legal climate relating to the practice of gene patenting. Lays bare the theoretical assumptions that underpin the injustice of patents on unmodified genes Makes a unique argument for a commons-by-necessity, explaining how parts of the universe are simply not susceptible to monopoly claims Represents the only work that attempts to first define the nature of the genetic objects involved before any ethical conclusions are reached Provides the most comprehensive accounting of the various lawsuits, legislative changes, and the public debate surrounding AMP v. Myriad, the most significant case regarding gene patents
A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.
Colin Farrelly contemplates the various ethical and social quandaries raised by the genetic revolution. Recent biomedical advances such as genetic screening, gene therapy and genome editing might be used to promote equality of opportunity, reproductive freedom, healthy aging, and the prevention and treatment of disease. But these technologies also raise a host of ethical questions: Is the idea of “genetically engineering” humans a morally objectionable form of eugenics? Should parents undergoing IVF be permitted to screen embryos for the sex of their offspring? Would it be ethical to alter the rate at which humans age, greatly increasing longevity at a time when the human population is already at potentially unsustainable levels? Farrelly applies an original virtue ethics framework to assess these and other challenges posed by the genetic revolution. Chapters discuss virtue ethics in relation to eugenics, infectious and chronic disease, evolutionary biology, epigenetics, happiness, reproductive freedom and longevity. This fresh approach creates a roadmap for thinking ethically about technological progress that will be of practical use to ethicists and scientists for years to come. Accessible in tone and compellingly argued, this book is an ideal introduction for students of bioethics, applied ethics, biomedical sciences, and related courses in philosophy and life sciences.
