The Electrophysiology of Neuroendocrine Cells

The Electrophysiology of Neuroendocrine Cells

Author: Hans Scherubl

Publisher: CRC Press

Published: 1995-08-21

Total Pages: 388

ISBN-13: 9780849324772

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The Electrophysiology of Neuroendocrine Cells explores the role of electrical activity in neuroendocrine cells in stimulus-secretion coupling, sensory mechanisms, and intercellular communication. This comprehensive and concise handbook includes introductory material on the ontogenesis and classification of the neuroendocrine system and describes general electrical properties, voltage-gated ion channels, and the pharmacology of ion channels. By focusing on functional aspects, The Electrophysiology of Neuroendocrine Cells provides research scientists, physicians, and students with a basic understanding of neuroendocrine cells and their similarity to neurones, as well as their relationship to thyroid- or steroid-hormone secreting endocrine cells. The multidisciplinary nature of this book provides readers with a broad perspective on the electrical properties of neuroendocrine cells, and the combination of general information and specialized information makes the book accessible to beginning and advanced readers alike.


Network Functions and Plasticity

Network Functions and Plasticity

Author: Jian Jing

Publisher: Academic Press

Published: 2017-04-11

Total Pages: 394

ISBN-13: 0128034998

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Network Functions and Plasticity: Perspectives from Studying Neuronal Electrical Coupling in Microcircuits focuses on the specific roles of electrical coupling in tractable, well-defined circuits, highlighting current research that offers novel insights for electrical coupling's roles in sensory and motor functions, neural computations, decision-making, regulation of network activity, circuit development, and learning and memory. Bringing together a diverse group of international experts and their contributions using a variety of approaches to study different invertebrate and vertebrate model systems with a focus on the role of electrical coupling/gap junctions in microcircuits, this book presents a timely contribution for students and researchers alike. - Provides an easy-to-read introduction on neural circuits of the model system - Focuses on the specific roles of electrical coupling in tractable, well-defined circuits - Includes recent discoveries and findings that are presented in the context of historical background - Outlines outstanding issues and future research in the field


Glial-Neuronal Signaling in Neuroendocrine Systems

Glial-Neuronal Signaling in Neuroendocrine Systems

Author: Jeffrey G. Tasker

Publisher:

Published: 2021

Total Pages: 0

ISBN-13: 9783030623845

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This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today. Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication. Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems. This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology.


Neuroendocrinology in Physiology and Medicine

Neuroendocrinology in Physiology and Medicine

Author: P. Michael Conn

Publisher: Springer Science & Business Media

Published: 1999-10-06

Total Pages: 560

ISBN-13: 1592597076

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A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by which the brain acts as an endocrine organ, not only to control hormonal functions, but also to maintain homeostasis and regulate behavior. The authors-recognized both as leaders in their fields and as skilled teachers-provide systematic coverage of the analytical, anatomical, functional, clinical, and pathological aspects of neuroendocrinology. Topics range from the interactions between the nervous and endocrine systems to the regulation of reproduction, development, metabolism, fluid balance, and biological rhythms. Neuroendocrinology in Physiology and Medicine offers an unprecedented marriage of clinical and basic knowledge that has been missing from classical neuroscience, endocrinology, and physiology texts. It will teach today's medical students and serve researchers as a valuable reference to this rapidly growing field.


Encyclopedic Reference of Cancer

Encyclopedic Reference of Cancer

Author: Manfred Schwab

Publisher: Springer Science & Business Media

Published: 2001-10-15

Total Pages: 1017

ISBN-13: 3540665277

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This comprehensive encyclopedic reference provides rapid and focused information about topics of cancer research for the clinical and basic scientist, students and informed laymen. It will be readily accessible, both electronically and in print, such that it will be of value to both the scientific community and the public.


A Time for Metabolism and Hormones

A Time for Metabolism and Hormones

Author: Paolo Sassone-Corsi

Publisher: Springer

Published: 2016-04-04

Total Pages: 141

ISBN-13: 3319270699

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Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.


Cellular Regulation of Secretion and Release

Cellular Regulation of Secretion and Release

Author: P. Michael Conn

Publisher: Elsevier

Published: 2013-09-24

Total Pages: 612

ISBN-13: 1483273563

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Cellular Regulation of Secretion and Release is a compilation of papers that deals with the processes in cellular perception of stimuli and the response to them. Part I describes the receptor occupancy and regulation of stimulus through the use of video image intensification techniques. This part also explains a model for the transmembrane regulation of adenylate cyclase that shows the mechanisms that cells use in sensing and responding to extracellular conditions. Part II discusses the early responses of secretory cells including changes in phospholipid metabolism, in electrophysiological events, and in macromolecular carboxymethylation. One paper suggests that protein-carboxyl methylase has a role in neurotransmission and secretion whether as a part of the exocytotic process or just a help to regulate the process. Part III addresses the role in secretion of the subcellular architecture particularly as regards the role of the cytoskeleton in endocrine function or insulin secretion and cytoskeletal proteins. Part IV discusses the synthesis, processing, and storage of secretory products, including the role of signal peptides, their properties, and interactions. Part V addresses the mechanisms and modulation of secretion and release in a study of Leydig cells. One paper concludes that the regulation of release, through dopamine and TRH factors, can have more than one mechanism of action. This book can be useful for cellular microbiologists, bacteriologists, endocrinologists, researchers, and academicians in the biochemistry and in reproductive medicine.


Neurophysiology of Neuroendocrine Neurons

Neurophysiology of Neuroendocrine Neurons

Author: William E. Armstrong

Publisher: John Wiley & Sons

Published: 2014-10-07

Total Pages: 391

ISBN-13: 1118606779

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Neurophysiology of Neuroendocrine Neurons provides researchers and students with not only an understanding of neuroendocrine cell electrophysiology, but also an appreciation of how this model system affords access to virtually all parts of the neuron for detailed study - something unique compared to most types of neuron in the brain. Chapters range from those describing the rich history and current state of in vivo recordings, highlighting the precise relationship between the patterns of action potential discharge in these neurons and hormone release, to in vitro approaches where neuroendocrine neurons can be precisely identified and their membrane properties, morphology, and synaptic responses, directly examined. • Written by a team of internationally renowned researchers, each chapter presents a succinct summary of the very latest developments in the field • Includes an evaluation of different experimental approaches, both in vivo and in vitro, and how the resulting data are interpreted • Both print and enhanced e-book versions are available • Illustrated in full colour throughout This is the first volume in a new Series ‘Masterclass in Neuroendocrinology’ , a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.


Neuroplasticity, Development, and Steroid Hormone Action

Neuroplasticity, Development, and Steroid Hormone Action

Author: Robert J. Handa

Publisher: CRC Press

Published: 2001-07-30

Total Pages: 427

ISBN-13: 1420041193

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A compilation of cutting-edge research, Neuroplasticity, Development, and Steroid Hormone Action explores the effects of steroid hormones on brain development, function, and aging. The experimental approaches used by the authors ranges from molecular to behavioral and endocrine to neurobiological. It contains scientific photographs, line drawings, tables, color illustrations, and graphs, this interesting and timely text covers the neuroplastic effects of steroid hormones throughout the lifetime of various animal models, such as bees, fish, lizards, turtles, birds, mice, rats, and primates.


Conn's Translational Neuroscience

Conn's Translational Neuroscience

Author: P. Michael Conn

Publisher: Academic Press

Published: 2016-09-28

Total Pages: 778

ISBN-13: 0128025964

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Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment