Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
This text provides a comprehensive, state-of-the-art overview of the diagnosis and management of the critically ill cirrhotic patient. The book reviews recent data about risk factors for acute on chronic liver failure (including infection, renal dysfunction and acute alcoholic hepatitis), profiles the latest treatment strategies for the management of variceal bleeding, ascites, hepatocellular carcinoma and presents current and novel therapies for acute hepatic encephalopathy, and anticoagulation in liver disease. The volume also focuses on the changing etiology of liver disease, with an emphasis on obesity and frailty/sarcopenia, and advances in surgical techniques, including living donor liver transplants and gender disparities in liver transplantation. Palliative care for the critically ill liver patient is also discussed in the book. Written by experts in the field, The Critically Ill Cirrhotic Patient: Evaluation and Management is a valuable resource for clinicians, practitioners, health care providers, and researchers who encounter patients with chronic liver disease, including end-stage liver cirrhosis.
There has been very little written on the interaction of the liverand kidney. This book addresses the increasing incidence andsignificance of diseases, such as ascites, renal dysfunction,cirrhosis and hypertension where both organs are involved. This textbook is essential, even for confirmed practitioners andcontains current information regarding treatment and therapy forpatients with cirrhosis and ascites, clearly and effectivelypresented by the top international experts within this field. The second edition is entirely revised and updated and placesgreater emphasis on therapy.
Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.
This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is unique in pathophysiological manifestations, underpinnings of physiology and treatment options. Patients with acute, chronic or acute on chronic liver failure are a growing fraction of ICU admissions. Hepatic Critical Care serves as the essential reference for both practicing intensivists at community hospitals and tertiary referral centers. This textbook is also targeted towards trainees specifically interested in taking care of patients with liver disease and liver transplantation.
A new, fully updated edition of the world’s most famous book on liver diseases—with updating of all areas and inclusion of new specific topics, by internationally renowned specialists This brand new edition of the classic book on hepatology provides a concise, clearly presented and well-structured review across the whole spectrum of hepatobiliary diseases by some of the world’s leading hepatologists and hepatobiliary specialists. Where many other hepatology textbooks provide detailed accounts of basic science and clinical management, Sherlock's Diseases of the Liver and Biliary System, 13th Edition takes a different approach. Concentrating on the clinical decisions to be taken and the relevant supporting data, it is written and edited to maintain Sheila Sherlock's unique approach, in particular the clarity and layout of the text, and the explanatory figures and tables. The book is thus concise, highly accessible, and generously illustrated with over 700 attractive color figures. There is a pithy approach to each disease based both on evidence and on the authors’ experience, the hallmark of this book. Based on these elements, the 12th edition was awarded first prize in the 2012 British Medical Association Book Awards in the Internal Medicine category. Sherlock's Diseases of the Liver and Biliary System begins by introducing the anatomy and function of the liver to readers, continuing then with in-depth coverage of liver biopsy techniques and interpretation, and fibrogenesis and its assessment. There are then chapters on all aspects of liver and biliary disease including acute liver failure, cirrhosis, portal hypertension, hepatic encephalopathy, ascites, hepatitis B and C, alcohol and the liver, non-alcoholic fatty liver disease, drug related liver reactions, cholestatic, autoimmune and genetic liver diseases, benign and malignant tumours and not least liver transplantation. There are also chapters on the liver in pregnancy, in the neonate, infancy and childhood, in systemic diseases and in infections. This new edition also features four new individual chapters focusing on coagulation, non-invasive assessment of fibrosis and cirrhosis; vascular diseases of the liver and portal vein thrombosis, and nutrition in liver disease. Digital downloads of the figures from this edition are offered on a companion website. Internationally recognized and loved, world-renowned hepatology book, first published in 1955 Takes a one-of-a-kind, clinical approach maintaining Sheila Sherlock’s clarity and legacy of presentation Full colour throughout with 700 illustrative figures Wide faculty of international contributors Sherlock's Diseases of the Liver and Biliary System, 13th Edition is an ideal primer in hepatology for students and trainees in hepatology and gastroenterology, and a valuable resource for all specialist gastroenterologists and hepatologists, paediatricians, pathologists, radiologists, general physicians and specialist nurses.
This book answers key questions asked by emergency clinicians faced with complex gastrointestinal and abdominal pain presentations. Instead of a traditional format that includes epidemiology, pathophysiology, diagnosis, and treatment options, this book takes an approach that mirrors the way clinicians interact with patients – by asking and answering specific clinical care questions. The book is organized into sections by presentation – gastrointestinal bleeding, for example – each of which contains chapters on specific questions, such as “What is the best clinical risk score for low risk GIB patients?” Each clinical question comes with a detailed, evidence-based response and a summary that gives best practices, recommendations, and references. Additionally, at the end of each section is a chapter titled “Expert Corner,” which asks the same clinical questions to a surgical or gastrointestinal specialist and includes key pearls these experts have for emergency medicine practitioners. Gastrointestinal Emergencies: Evidence-Based Answers to Key Clinical Questions is an essential guide for emergency medicine physicians, residents, and medical students who want to review and improve their care of acute gastrointestinal emergencies.
Practical clinical handbook reviewing all aspects of the diagnosis and management of intra-abdominal hypertension; essential reading for all critical care staff.
Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.
This unique book provides detailed insight into a wealth of expert experience in liver pathology, with an in-depth review of the expertÌs analysis and diagnostic process supported by high-quality color photomicrographs and discussion of the diagnostic principles involved in evaluating these lesions. The diagnostic problems and cases selected show the wide range of specimens seen in liver pathology and address the difficult issues in diagnosis encountered in these lesions. Chapters and cases are authored by many of the leading experts and educators in liver pathology today. Liver Pathology will be essential reading for every pathologist who evaluates liver pathology specimens. In addition it will be a valuable resource for pathology residents and fellows. All Consultant Pathology Titles Provide: Actual consultation cases and expert analysis Expert analysis provides a detailed discussion of the reasoning behind the diagnosis of each case Comprehensive coverage of challenging diagnoses The cases are richly illustrated with high-quality photomicrographs
