The Claustrum: charting a way forward for the brain’s most mysterious nucleus
The Claustrum: charting a way forward for the brain’s most mysterious nucleus

Author: Ariel Y. Deutch

Publisher: Frontiers Media SA

Published: 2015-09-09

Total Pages: 143

ISBN-13: 2889195422

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The claustrum is a long, band-like grey matter structure situated in the ventrolateral telencephalon of most, if not all, mammalian brains. Due to its shape and close proximity to white matter structures and insular cortex, the anatomy and behavioral relevance of the claustrum have proven difficult to study. As a result, disagreements in the literature exist over ontogeny, phylogeny, anatomical boundaries, and connectivity. Despite this, it is generally regarded that the claustrum contains excitatory projection neurons that reciprocally connect to most regions of the cerebral cortex, a feature that has fostered varying hypotheses as to its function. These hypotheses propose multisensory integration, coordination of cortical activity for the generation of conscious percepts, or saliency filtration. The articles of this e-book consider the historical and recent highlights in claustrum structure, hodology, and function and seek to provide a compelling way forward for this “hidden” nucleus.

Neuroanatomical Tract-Tracing
Neuroanatomical Tract-Tracing

Author: Laszlo Zaborszky

Publisher: Springer Science & Business Media

Published: 2006-11-22

Total Pages: 703

ISBN-13: 0387289429

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The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.

The Neurology of Consciousness
The Neurology of Consciousness

Author: Steven Laureys

Publisher: Academic Press

Published: 2015-08-12

Total Pages: 488

ISBN-13: 0128011750

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The second edition of The Neurology of Consciousness is a comprehensive update of this ground-breaking work on human consciousness, the first book in this area to summarize the neuroanatomical and functional underpinnings of consciousness by emphasizing a lesional approach offered by the study of neurological patients. Since the publication of the first edition in 2009, new methodologies have made consciousness much more accessible scientifically, and, in particular, the study of disorders, disruptions, and disturbances of consciousness has added tremendously to our understanding of the biological basis of human consciousness. The publication of a new edition is both critical and timely for continued understanding of the field of consciousness. In this critical and timely update, revised and new contributions by internationally renowned researchers—edited by the leaders in the field of consciousness research—provide a unique and comprehensive focus on human consciousness. The new edition of The Neurobiology of Consciousness will continue to be an indispensable resource for researchers and students working on the cognitive neuroscience of consciousness and related disorders, as well as for neuroscientists, psychologists, psychiatrists, and neurologists contemplating consciousness as one of the philosophical, ethical, sociological, political, and religious questions of our time. - New chapters on the neuroanatomical basis of consciousness and short-term memory, and expanded coverage of comas and neuroethics, including the ethics of brain death - The first comprehensive, authoritative collection to describe disorders of consciousness and how they are used to study and understand the neural correlates of conscious perception in humans. - Includes both revised and new chapters from the top international researchers in the field, including Christof Koch, Marcus Raichle, Nicholas Schiff, Joseph Fins, and Michael Gazzaniga

Fundamental Neuroscience
Fundamental Neuroscience

Author: Larry Squire

Publisher: Academic Press

Published: 2008-04-02

Total Pages: 1277

ISBN-13: 0080561020

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Fundamental Neuroscience, Third Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts.Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness Additional text boxes describing key experiments, disorders, methods, and concepts Multiple model system coverage beyond rats, mice, and monkeys Extensively expanded index for easier referencing

Sleep-Wake Neurobiology and Pharmacology
Sleep-Wake Neurobiology and Pharmacology

Author: Hans-Peter Landolt

Publisher: Springer Nature

Published: 2019-09-03

Total Pages: 473

ISBN-13: 3030112721

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This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com

Progressive Brain Disorders in Childhood
Progressive Brain Disorders in Childhood

Author: Juan M. Pascual

Publisher: Cambridge University Press

Published: 2017-04-20

Total Pages: 507

ISBN-13: 1107042054

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A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.

Large-scale Neuronal Theories of the Brain
Large-scale Neuronal Theories of the Brain

Author: Christof Koch

Publisher: MIT Press

Published: 1994

Total Pages: 376

ISBN-13: 9780262111836

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This book originated at a small and informal workshop held in December of 1992 in Idyllwild, a relatively secluded resort village situated amid forests in the San Jacinto Mountains above Palm Springs in Southern California. Eighteen colleagues from a broad range of disciplines, including biophysics, electrophysiology, neuroanatomy, psychophysics, clinical studies, mathematics and computer vision, discussed 'Large Scale Models of the Brain, ' that is, theories and models that cover a broad range of phenomena, including early and late vision, various memory systems, selective attention, and the neuronal code underlying figure-ground segregation and awareness (for a brief summary of this meeting, see Stevens 1993). The bias in the selection of the speakers toward researchers in the area of visual perception reflects both the academic background of one of the organizers as well as the (relative) more mature status of vision compared with other modalities. This should not be surprising given the emphasis we humans place on'seeing' for orienting ourselves, as well as the intense scrutiny visual processes have received due to their obvious usefullness in military, industrial, and robotic applications. JMD.

The Claustrum
The Claustrum

Author: John R. Smythies

Publisher: Academic Press

Published: 2013-11-11

Total Pages: 408

ISBN-13: 012404722X

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The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum's two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain's orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. - Develops a unifying hypothesis about the claustrum's role in consciousness, as well as the integration of sensory information and other higher brain functions - Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer's disease, and Parkinson's disease - Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts

Stereotaxic Atlas of the Pig Brain
Stereotaxic Atlas of the Pig Brain

Author: B. Félix

Publisher:

Published: 1999-10-18

Total Pages: 152

ISBN-13:

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This is an excellently reproduced stereotaxic atlas of the pig brain. It consists of 60 frontal and 18 sagittal drawings illustrating Nissl-stained sections. A stereotaxic apparatus adapted for the Pig was used to determine the barin coordinates. Radiographic techniques were applied to verify the correct position of the central nervous system structures in the apparatus. The atlas gives frontal and sagittal serial sections of 100&mgr;m, performed in two different animals. Magnified diagrams of brain sections representing the cellular architecture of the brain structures were produced, some of which are illustrated with photomicrographs. Each plate is accompanied by a list of abbreviations used to label structures on the plate, together with the terms which they represent. This work will be a very useful anatomical guide for research on the pig brain.