Finding What Works in Health Care

Finding What Works in Health Care

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2011-07-20

Total Pages: 267

ISBN-13: 0309164257

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Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.


My Margot

My Margot

Author: Ken Ludden

Publisher: Lulu.com

Published: 2014-07-02

Total Pages: 438

ISBN-13: 1312324163

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Margot Fonteyn's closest friends don't appear in Daneman's detailed biography. Lita Legarda (a doctor) gets a one line mention. Angie Novello (Margot's Washington Hostess), Theodora Christon (Margot's personal secretary) and Ken Ludden aren't mentioned at all. These were the people she trusted most, who kept her confidences and never spoke to the press. Everyone knew Margot differently. BQ, her mother, knew one Margot. Tito, her husband, knew another. Ludden, her circle's youngest by a large margin, knew yet another side of Margot: hence the title 'My Margot'. Ken shares that Margot--who taught him so much about ballet and life, and with whom he worked to plan ballet's future. Beyond Margot we learn about Ken's delightful relationship with BQ, a close friendship between a teenager and a woman of eighty. Ken also writes with unflinching honesty of the hostile relationship he had with Rudolf Nureyev, which developed over time into a grudging mutual respect and a shared grief when Margot died.


Educational Research

Educational Research

Author: John W. Creswell

Publisher:

Published: 2015

Total Pages: 0

ISBN-13: 9780133831535

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"Educational Research: Planning, Conducting, and Evaluating Quantitative and Qualitative Research offers a truly balanced, inclusive, and integrated overview of the processes involved in educational research. This text first examines the general steps in the research process and then details the procedures for conducting specific types of quantitative, qualitative, and mixed methods studies. Direct guidance on reading research is offered throughout the text, and interactive features provide opportunities for practice."--Publisher's description.


The Royal Road to Romance

The Royal Road to Romance

Author: Richard Halliburton

Publisher:

Published: 1925

Total Pages: 510

ISBN-13:

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When Richard Halliburton graduated from college, he chose adventure over a career, traveling the world with almost no money. The Royal Road to Romance chronicles what happened as a result, from a breakthrough Matterhorn ascent to being jailed for taking forbidden pictures on Gibraltar. Halliburton's literary career developed out of his meticulous logging of events that occurred on his own adventures. This book, his first, an account of his travels in 1921-23, was a best-seller for three years and was translated into 15 languages.


The Prokaryotes

The Prokaryotes

Author: Edward F. DeLong

Publisher: Springer

Published: 2013-03-22

Total Pages: 662

ISBN-13: 9783642301421

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The Prokaryotes is a comprehensive, multi-authored, peer reviewed reference work on Bacteria and Achaea. This fourth edition of The Prokaryotes is organized to cover all taxonomic diversity, using the family level to delineate chapters. Different from other resources, this new Springer product includes not only taxonomy, but also prokaryotic biology and technology of taxa in a broad context. Technological aspects highlight the usefulness of prokaryotes in processes and products, including biocontrol agents and as genetics tools. The content of the expanded fourth edition is divided into two parts: Part 1 contains review chapters dealing with the most important general concepts in molecular, applied and general prokaryote biology; Part 2 describes the known properties of specific taxonomic groups. Two completely new sections have been added to Part 1: bacterial communities and human bacteriology. The bacterial communities section reflects the growing realization that studies on pure cultures of bacteria have led to an incomplete picture of the microbial world for two fundamental reasons: the vast majority of bacteria in soil, water and associated with biological tissues are currently not culturable, and that an understanding of microbial ecology requires knowledge on how different bacterial species interact with each other in their natural environment. The new section on human microbiology deals with bacteria associated with healthy humans and bacterial pathogenesis. Each of the major human diseases caused by bacteria is reviewed, from identifying the pathogens by classical clinical and non-culturing techniques to the biochemical mechanisms of the disease process. The 4th edition of The Prokaryotes is the most complete resource on the biology of prokaryotes. The following volumes are published consecutively within the 4th Edition: Prokaryotic Biology and Symbiotic Associations Prokaryotic Communities and Ecophysiology Prokaryotic Physiology and Biochemistry Applied Bacteriology and Biotechnology Human Microbiology Actinobacteria Firmicutes Alphaproteobacteria and Betaproteobacteria Gammaproteobacteria Deltaproteobacteria and Epsilonproteobacteria Other Major Lineages of Bacteria and the Archaea


Histidine Kinases in Signal Transduction

Histidine Kinases in Signal Transduction

Author: Masayori Inouye

Publisher: Elsevier

Published: 2002-11-13

Total Pages: 539

ISBN-13: 0080534015

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Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions. Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes. An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool. The first comprehensive book on the roles of histidine kinases in cells 23 in-depth chapters written by leading experts in the field Describes the most recent advances in the field of signal transduction


Cochrane Handbook for Systematic Reviews of Interventions

Cochrane Handbook for Systematic Reviews of Interventions

Author: Julian P. T. Higgins

Publisher: Wiley

Published: 2008-11-24

Total Pages: 672

ISBN-13: 9780470699515

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Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.