The Anthrax Vaccine

The Anthrax Vaccine

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2002-04-18

Total Pages: 288

ISBN-13: 0309182743

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The vaccine used to protect humans against the anthrax disease, called Anthrax Vaccine Adsorbed (AVA), was licensed in 1970. It was initially used to protect people who might be exposed to anthrax where they worked, such as veterinarians and textile plant workers who process animal hair. When the U. S. military began to administer the vaccine, then extended a plan for the mandatory vaccination of all U. S. service members, some raised concerns about the safety and efficacy of AVA and the manufacture of the vaccine. In response to these and other concerns, Congress directed the Department of Defense to support an independent examination of AVA. The Anthrax Vaccine: Is It Safe? Does It Work? reports the study's conclusion that the vaccine is acceptably safe and effective in protecting humans against anthrax. The book also includes a description of advances needed in main areas: improving the way the vaccine is now used, expanding surveillance efforts to detect side effects from its use, and developing a better vaccine.


Anthrax in Humans and Animals

Anthrax in Humans and Animals

Author: World Health Organization

Publisher: World Health Organization

Published: 2008

Total Pages: 219

ISBN-13: 9241547537

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This fourth edition of the anthrax guidelines encompasses a systematic review of the extensive new scientific literature and relevant publications up to end 2007 including all the new information that emerged in the 3-4 years after the anthrax letter events. This updated edition provides information on the disease and its importance, its etiology and ecology, and offers guidance on the detection, diagnostic, epidemiology, disinfection and decontamination, treatment and prophylaxis procedures, as well as control and surveillance processes for anthrax in humans and animals. With two rounds of a rigorous peer-review process, it is a relevant source of information for the management of anthrax in humans and animals.


Immunization

Immunization

Author: Stuart Blume

Publisher: Reaktion Books

Published: 2017-08-15

Total Pages: 280

ISBN-13: 1780238681

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As the world pins its hope for the end of the coronavirus pandemic to the successful rollout of vaccines, this book offers a vital long view of such efforts—and our resistance to them. At a time when vaccines are a vital tool in the fight against COVID-19 in all its various mutations, this hard-hitting book takes a longer historical perspective. It argues that globalization and cuts to healthcare have been eroding faith in the institutions producing and providing vaccines for more than thirty years. It tells the history of immunization from the work of early pioneers such as Louis Pasteur and Robert Koch through the eradication of smallpox in 1980, to the recent introduction of new kinds of genetically engineered vaccines. Immunization exposes the limits of public health authorities while suggesting how they can restore our confidence. Public health experts and all those considering vaccinations should read this timely history.


Vaccine

Vaccine

Author: Mark A. Largent

Publisher: JHU Press

Published: 2012-09

Total Pages: 233

ISBN-13: 1421406071

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A thoughtful evaluation of the vaccine debate, its history, and its consequences. Since 1990, the number of mandated vaccines has increased dramatically. Today, a fully vaccinated child will have received nearly three dozen vaccinations between birth and age six. Along with the increase in number has come a growing wave of concern among parents about the unintended side effects of vaccines. In Vaccine, Mark A. Largent explains the history of the debate and identifies issues that parents, pediatricians, politicians, and public health officials must address. Nearly 40% of American parents report that they delay or refuse a recommended vaccine for their children. Despite assurances from every mainstream scientific and medical institution, parents continue to be haunted by the question of whether vaccines cause autism. In response, health officials herald vaccines as both safe and vital to the public's health and put programs and regulations in place to encourage parents to follow the recommended vaccine schedule. For Largent, the vaccine-autism debate obscures a constellation of concerns held by many parents, including anxiety about the number of vaccines required (including some for diseases that children are unlikely ever to encounter), unhappiness about the rigorous schedule of vaccines during well-baby visits, and fear of potential side effects, some of them serious and even life-threatening. This book disentangles competing claims, opens the controversy for critical reflection, and provides recommendations for moving forward.


Values and Vaccine Refusal

Values and Vaccine Refusal

Author: Mark Navin

Publisher: Routledge

Published: 2015-09-16

Total Pages: 250

ISBN-13: 131765319X

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Parents in the US and other societies are increasingly refusing to vaccinate their children, even though popular anti-vaccine myths – e.g. ‘vaccines cause autism’ – have been debunked. This book explains the epistemic and moral failures that lead some parents to refuse to vaccinate their children. First, some parents have good reasons not to defer to the expertise of physicians, and to rely instead upon their own judgments about how to care for their children. Unfortunately, epistemic self-reliance systematically distorts beliefs in areas of inquiry in which expertise is required (like vaccine immunology). Second, vaccine refusers and mainstream medical authorities are often committed to different values surrounding health and safety. For example, while vaccine advocates stress that vaccines have low rates of serious complications, vaccine refusers often resist vaccination because it is ‘unnatural’ and because they view vaccine-preventable diseases as a ‘natural’ part of childhood. Finally, parents who refuse vaccines rightly resist the utilitarian moral arguments – ‘for the greater good’ – that vaccine advocates sometimes make. Unfortunately, vaccine refusers also sometimes embrace a pernicious hyper-individualism that sanctions free-riding on herd immunity and that cultivates indifference to the interpersonal and social harms that unvaccinated persons may cause.


Adverse Effects of Vaccines

Adverse Effects of Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-04-26

Total Pages: 894

ISBN-13: 0309214351

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In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.


The Panic Virus

The Panic Virus

Author: Seth Mnookin

Publisher: Simon and Schuster

Published: 2012-01-03

Total Pages: 466

ISBN-13: 1439158657

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A searing account of how vaccine opponents have used the media to spread their message of panic, despite no scientific evidence to support them.


The Private Science of Louis Pasteur

The Private Science of Louis Pasteur

Author: Gerald L. Geison

Publisher: Princeton University Press

Published: 2014-07-14

Total Pages: 417

ISBN-13: 1400864089

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In The Private Science of Louis Pasteur, Gerald Geison has written a controversial biography that finally penetrates the secrecy that has surrounded much of this legendary scientist's laboratory work. Geison uses Pasteur's laboratory notebooks, made available only recently, and his published papers to present a rich and full account of some of the most famous episodes in the history of science and their darker sides--for example, Pasteur's rush to develop the rabies vaccine and the human risks his haste entailed. The discrepancies between the public record and the "private science" of Louis Pasteur tell us as much about the man as they do about the highly competitive and political world he learned to master. Although experimental ingenuity served Pasteur well, he also owed much of his success to the polemical virtuosity and political savvy that won him unprecedented financial support from the French state during the late nineteenth century. But a close look at his greatest achievements raises ethical issues. In the case of Pasteur's widely publicized anthrax vaccine, Geison reveals its initial defects and how Pasteur, in order to avoid embarrassment, secretly incorporated a rival colleague's findings to make his version of the vaccine work. Pasteur's premature decision to apply his rabies treatment to his first animal-bite victims raises even deeper questions and must be understood not only in terms of the ethics of human experimentation and scientific method, but also in light of Pasteur's shift from a biological theory of immunity to a chemical theory--similar to ones he had often disparaged when advanced by his competitors. Through his vivid reconstruction of the professional rivalries as well as the national adulation that surrounded Pasteur, Geison places him in his wider cultural context. In giving Pasteur the close scrutiny his fame and achievements deserve, Geison's book offers compelling reading for anyone interested in the social and ethical dimensions of science. Originally published in 1995. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.