Aminoglycoside Antibiotics

Aminoglycoside Antibiotics

Author: Dev P. Arya

Publisher: John Wiley & Sons

Published: 2007-06-29

Total Pages: 338

ISBN-13: 047174302X

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Advances that open new avenues in developing aminoglycoside antibiotics During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and opened up new therapeutic targets for intervention. This is the first book to provide a complete overview of recent advances in the field and explore their tremendous potential for drug discovery and rational drug design. With chapters written by one or more leading experts in their specialty areas, the book addresses the chemistry, biology, and toxicology of aminoglycosides. Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery is a great resource for academic and industrial researchers in drug design and mechanism studies and for researchers studying antibiotic resistance, antibiotic design and synthesis, and the discovery of novel pharmaceuticals. It is also a valuable reference for graduate students in pharmacy, pharmaceutical science, biophysics, medicinal chemistry, and chemical biology.


Aminoglycosides—Advances in Research and Application: 2012 Edition

Aminoglycosides—Advances in Research and Application: 2012 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-12-26

Total Pages: 73

ISBN-13: 148161049X

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Aminoglycosides—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Aminoglycosides in a concise format. The editors have built Aminoglycosides—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Aminoglycosides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Aminoglycosides—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Handbook on Biological Warfare Preparedness

Handbook on Biological Warfare Preparedness

Author: S.J.S. Flora

Publisher: Academic Press

Published: 2019-10-05

Total Pages: 306

ISBN-13: 012812055X

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Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection


Antimicrobial Chemotherapy

Antimicrobial Chemotherapy

Author: Roger Finch

Publisher: OUP Oxford

Published: 2012-01-05

Total Pages: 409

ISBN-13: 0191628654

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Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.


Antimicrobial Resistance in Agriculture

Antimicrobial Resistance in Agriculture

Author: Indranil Samanta

Publisher: Academic Press

Published: 2019-09-25

Total Pages: 392

ISBN-13: 0128165235

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Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans. Explores all the genera of livestock and fish originated pathogenic bacteria associated with antimicrobial resistance Presents cutting-edge research on epigenetics, nanotechnology and intervention technologies Discusses transmission dynamics of resistance gene pools from different reservoirs, including food animals, poultry, fishes and the environment


Oxford Handbook of Infectious Diseases and Microbiology

Oxford Handbook of Infectious Diseases and Microbiology

Author: Estée Török

Publisher: Oxford University Press

Published: 2017

Total Pages: 914

ISBN-13: 019967132X

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This handbook takes an integrated approach to both infectious disease and microbiology. Referenced to national frameworks and current legislation, it covers basic principles of bacteriology and virology, specific information on diseases and conditions, and material on 'hot topics' such as bioterrorism and preventative medicine.


Aminoglycosides

Aminoglycosides

Author: Ruthie Alves

Publisher: Nova Biomedical Books

Published: 2016

Total Pages: 0

ISBN-13: 9781536101713

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Aminoglycosides are a commonly used class of antibiotic worldwide, with examples including gentamicin, tobramycin and amikacin. Their low cost, together with their effectiveness against Gram-negative organisms, including Pseudomonas aeruginosa, makes them a valuable tool in treating infections. In addition, aminoglycosides have demonstrated lower rates of resistance in both community and healthcare settings when compared with many other antimicrobials and exhibit synergistic activity with beta-lactams against certain Gram-positive organisms, such as streptococcus and enterococcus. Unfortunately, aminoglycosides exhibit a narrow therapeutic index, which can result in toxicity if care is not taken with their use. This book reviews the pharmacology, clinical uses and health effects of aminoglycosides.