The Biochemistry of Alkaloids
The Biochemistry of Alkaloids

Author: Trevor Robinson

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 159

ISBN-13: 3662010151

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The alkaloids were of great importance to mankind for centuries, long before they were recognized as a chemical class. The influence they have had on literature is hinted at by some of the quotations I have used as chapter headings. Their in fluence on folklore and on medicine has been even greater. The scientific study of alkaloids may be said to have begun with the isolation of morphine by SERTURNER in 1804. Since that time they have remained of great interest to chemists, and now in any month there appear dozens of publications dealing with the isolation of new alkaloids or the determination of the structures of previously known ones. The area of alkaloid biochemistry, in comparison, has received little attention, and today is much less developed. There is a certain amount of personal arbitrariness in defining "biochemistry", as there is in defining "alkaloid", and this arbitrariness is doubtless compounded by the combination. Nevertheless, it seems to me that in any consideration of the bio chemistry of a group of compounds three aspects are always worthy of attention pathways of biosynthesis, function or activity, and pathways of degradation. For the alkaloids, treatment of these three aspects is necessarily lopsided. Much has been learned about routes of biosynthesis, but information on the other aspects is very scanty. It would be possible to enter into some speculation regarding the biosyn thesis of all the more than 1,000 known alkaloids.

Natural Products
Natural Products

Author: Kishan Gopal Ramawat

Publisher: Springer

Published: 2013-06-28

Total Pages: 0

ISBN-13: 9783642221439

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This reference work provides a wealth of information regarding medicinal plants and phytochemicals. It is addressed both to researchers and teachers. The handbook describes phytochemicals, which, by the strictest definition, are chemicals that are produced by plants. During the last decades, more and more groups became actively involved in exploring plants for useful metabolites that lead to the identification of several useful curative agents and many promising molecules to fight and/or prevent diseases, including carcinogenesis and stroke. But when we talk about phytochemicals, there are also medicinal plants where not a single molecule is responsible for the observed properties. This reference work therefore reviews and compiles the information on both these aspects. The volumes contain contributions on phytochemicals and herbal extracts. A large number of natural products obtained from plants and microorganisms is used in cosmetic, drug, flavor and fragrance industries. For this compilation, a range of the most important medicinal herbs and phytochemicals were selected and are described by the recognized authors in the field. The present reference work encompasses the information about well established phytochemicals, biology and biotechnology of medicinal plants or their products, their biosynthesis, novel production strategies, demand and uses, metabolism and bioavailability. There is a surge of information published in recent years on herbal medicine and their pharmacologic effects with single books available on varied subjects. However, all this information is widespread and difficult to overview. Researchers who wish to keep a pace with the rapidly developing field of natural products can now consult this newly compiled handbook to find all information about bioactive molecules and medicinal plants thoroughly compiled in one place!

Terpenoids and Steroids
Terpenoids and Steroids

Author: K H Overton

Publisher: Royal Society of Chemistry

Published: 2007-10-31

Total Pages: 571

ISBN-13: 1847557007

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Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Terpenes and Terpenoids
Terpenes and Terpenoids

Author: Shagufta Perveen

Publisher: BoD – Books on Demand

Published: 2018-12-19

Total Pages: 154

ISBN-13: 1789847761

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Terpenes belong to the diverse class of chemical constituents isolated from materials found in nature (plants, fungi, insects, marine organisms, plant pathogens, animals and endophytes). These metabolites have simple to complex structures derived from Isopentyl diphosphate (IPP), dimethyl allyl diphosphate (DMAPP), mevalonate and deoxyxylulose biosynthetic pathways. Terpenes play a very important role in human health and have significant biological activities (anticancer, antimicrobial, anti-inflammatory, antioxidant, antiallergic, skin permeation enhancer, anti-diabetic, immunomodulatory, anti-insecticidal). This book gives an overview and highlights recent research in the phytochemical and biological understanding of terpenes and terpenoid and explains the most essential functions of these kinds of secondary metabolites isolated from natural sources.

Medicinal Plant Research in Africa
Medicinal Plant Research in Africa

Author: Victor Kuete

Publisher: Newnes

Published: 2013-06-19

Total Pages: 917

ISBN-13: 0124059368

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The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. - The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites - This book explores the essence of natural substances from African medicinal plants and their pharmacological potential - The authors are world reknowned African Scientists

A Fragrant Introduction to Terpenoid Chemistry
A Fragrant Introduction to Terpenoid Chemistry

Author: Charles S Sell

Publisher: Royal Society of Chemistry

Published: 2019-05-16

Total Pages: 432

ISBN-13: 178801832X

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Terpenoids play an important part in all our lives, from Vitamin A and hormones to perfumes and pharmaceuticals. This book provides an introduction to terpenoid chemistry, concentrating on the lower terpenoids, but the basic principles taught are also the foundation for the chemistry of the higher terpenoids. Coverage includes: the biogenesis of terpenoids; some of the history of the field; the principles of structural determination; and the importance of stereochemistry and stereoselective synthesis. Carbocation chemistry is introduced, as are the principles of total and partial synthesis. Finally, industrial chemistry (both discovery chemistry and chemical process development) is discussed, using the volatile terpenoids of perfumery to illustrate basic concepts. Ideal as both an introduction to terpenoid chemistry and as a refresher course, A Fragrant Introduction to Terpenoid Chemistry, with its real-life problems and appreciation of the relevance of chemistry to everyday life, will prove invaluable to students, lecturers and industrialists alike.

Organic Geochemistry
Organic Geochemistry

Author: Geoffrey Eglinton

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 850

ISBN-13: 3642877346

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For many years, the subject matter encompassed by the title of this book was largely limited to those who were interested in the two most economically important organic materials found buried in the Earth, namely, coal and petroleum. The point of view of any discussions which might occur, either in scientific meetings or in books that have been written, was, therefore, dominated largely by these interests. A great change has occurred in the last decade. This change had as its prime mover our growing knowledge of the molecular architecture of biological systems which, in turn, gave rise to a more legitimate asking of the question: "How did life come to be on the surface of the Earth?" A second motivation arose when the possibilities for the exploration of planets other than the Earth-the moon, Mars, and other parts of the solar system-became a reality. Thus the question of the possible existence of life elsewhere than on Earth conceivably could be answered.

Natural Products
Natural Products

Author: Lixin Zhang

Publisher: Springer Science & Business Media

Published: 2007-11-17

Total Pages: 380

ISBN-13: 1592599761

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A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.

Plant Secondary Metabolism
Plant Secondary Metabolism

Author: David S. Seigler

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 766

ISBN-13: 1461549132

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Life has evolved as a unified system; no organism exists similar role also has been suggested for fatty acids from alone, but each is in intimate contact with other organisms cyanolipids. Nonprotein amino acids, cyanogenic glyco and its environment. Historically, it was easier for workers sides, and the non-fatty-acid portion of cyanolipids also are in various disciplines to delimit artificially their respective incorporated into primary metabolites during germination. areas of research, rather than attempt to understand the entire Secondary metabolites of these structural types are accumu system of living organisms. This was a pragmatic and neces lated in large quantities in the seeds of several plant groups sary way to develop an understanding for the various parts. where they probably fulfill an additional function as deter We are now at a point, however, where we need to investi rents to general predation. gate those things common to the parts and, specifically, those The second type of relationship involves interaction of things that unify the parts. The fundamental aspects of many plants with other organisms and with their environment. Bio of these interactions are chemical in nature. Plants constitute logical interactions must be viewed in the light of evolution an essential part of all life systems; phytochemistry provides ary change and the coadaptation, or perhaps coevolution, of a medium for linking several fields of study.

Terpenes
Terpenes

Author: Eberhard Breitmaier

Publisher: John Wiley & Sons

Published: 2006-12-13

Total Pages: 223

ISBN-13: 3527609105

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This concise overview of terpenes and their applications covers the structure, natural sources, biological and pharmacological effects, as well as selected total syntheses of the compound. This book includes a chapter on structure determination, as well as added information on biogenesis, polycyclic terpenes, gingkoloids and neo-hopanes. This title is an ideal introductory book for anybody starting work in this field.