Technical Report on Toxicology and Carcinogenesis Studies of Methylene Blue Trihydrate (CAS No. 7220-79-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
Technical Report on Toxicology and Carcinogenesis Studies of Methylene Blue Trihydrate (CAS No. 7220-79-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Author: D. W. Bristol

Publisher: DIANE Publishing

Published: 2008-10

Total Pages: 252

ISBN-13: 1437906613

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Methylene Blue Trihydrate (MBT) has a variety of biomedical and biologically therapeutic applications. MBT was nominated by the Nat. Cancer Inst. for carcinogenecity testing based on the numerous uses of this compound and the lack of long-term toxicity data, including epidemiological studies of MBT, as well as the inadequate animal data on this compound. Male and female F344/N rats and B6C3F1 mice were administered MBT in 0.5% aqueous methylcellulose by gavage for 1 month, 3 months, or 2 years. Genetic toxicology studies were conducted using ¿Salmonella typhimurium,¿ ¿Escherichia coli,¿ cultured Chinese hamster ovary cells, mouse bone marrow cells, and mouse peripheral blood erythrocytes. Illustrations.

Biomaterials For Modern Cancer Imaging And Therapies: Methylene Blue For Fluorescence And Photoacoustic Imaging And Light-induced Cancer Therapy
Biomaterials For Modern Cancer Imaging And Therapies: Methylene Blue For Fluorescence And Photoacoustic Imaging And Light-induced Cancer Therapy

Author: Maoquan Chu

Publisher: World Scientific

Published: 2024-03-20

Total Pages: 177

ISBN-13: 9811277710

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Methylene blue (MB) is a biocompatible and environmentally friendly material that has been widely used in clinical and biomedical research fields for over a century. In addition, it also has wide applications in other fields, such as dyeing and finishing industry, aquaculture industry, photocatalysis and food industry.This landmark publication is unique as it covers MB-mediated in vivo fluorescence, photoacoustic imaging and light-induced cancer therapy. The optical properties and photothermal effect of MB are also systematically described.

Inflammatory Bowel Disease
Inflammatory Bowel Disease

Author: Russell D. Cohen

Publisher: Humana Press

Published: 2017-06-28

Total Pages: 366

ISBN-13: 3319537636

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The latest edition of this text provides a comprehensive overview of the “natural flow of knowledge” regarding inflammatory bowel disease, with an emphasis on state-of-the art approaches that should be the basis for diagnosis and treatment of most patients. In addition to updated chapters, this volume includes new chapters on such topics as the impending biosimilar revolution, quality of care, and new challenges to previously held beliefs about IBD diagnosis, treatment, and pathogenesis. The book is also one of the first to have a chapter written specifically by and for physician extenders in the training of colleagues and the treatment of patients, which is of increasing importance moving forward in the medical profession. Written by experts in the field, Inflammatory Bowel Disease: Diagnosis and Therapeutics, Third Edition is a valuable resource for physicians, nurses, researchers, and other health care providers interested in the latest cutting-edge knowledge for treating patients with inflammatory bowel disease.