Genomics in the Cloud

Genomics in the Cloud

Author: Geraldine A. Van der Auwera

Publisher: O'Reilly Media

Published: 2020-04-02

Total Pages: 496

ISBN-13: 1491975164

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Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytes—or over 50 million gigabytes—of genomic data, and they’re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud? With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian O’Connor of the UC Santa Cruz Genomics Institute, guide you through the process. You’ll learn by working with real data and genomics algorithms from the field. This book covers: Essential genomics and computing technology background Basic cloud computing operations Getting started with GATK, plus three major GATK Best Practices pipelines Automating analysis with scripted workflows using WDL and Cromwell Scaling up workflow execution in the cloud, including parallelization and cost optimization Interactive analysis in the cloud using Jupyter notebooks Secure collaboration and computational reproducibility using Terra


Cloud Computing and Big Data: Technologies, Applications and Security

Cloud Computing and Big Data: Technologies, Applications and Security

Author: Mostapha Zbakh

Publisher: Springer

Published: 2018-07-27

Total Pages: 406

ISBN-13: 3319977199

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This book addresses topics related to cloud and Big Data technologies, architecture and applications including distributed computing and data centers, cloud infrastructure and security, and end-user services. The majority of the book is devoted to the security aspects of cloud computing and Big Data. Cloud computing, which can be seen as any subscription-based or pay-per-use service that extends the Internet’s existing capabilities, has gained considerable attention from both academia and the IT industry as a new infrastructure requiring smaller investments in hardware platforms, staff training, or licensing software tools. It is a new paradigm that has ushered in a revolution in both data storage and computation. In parallel to this progress, Big Data technologies, which rely heavily on cloud computing platforms for both data storage and processing, have been developed and deployed at breathtaking speed. They are among the most frequently used technologies for developing applications and services in many fields, such as the web, health, and energy. Accordingly, cloud computing and Big Data technologies are two of the most central current and future research mainstreams. They involve and impact a host of fields, including business, scientific research, and public and private administration. Gathering extended versions of the best papers presented at the Third International Conference on Cloud Computing Technologies and Applications (CloudTech’17), this book offers a valuable resource for all Information System managers, researchers, students, developers, and policymakers involved in the technological and application aspects of cloud computing and Big Data.


Leveraging the Wisdom of the Crowd in Software Testing

Leveraging the Wisdom of the Crowd in Software Testing

Author: Mukesh Sharma

Publisher: CRC Press

Published: 2014-09-19

Total Pages: 178

ISBN-13: 1482254492

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Its scale, flexibility, cost effectiveness, and fast turnaround are just a few reasons why crowdsourced testing has received so much attention lately. While there are a few online resources that explain what crowdsourced testing is all about, there's been a need for a book that covers best practices, case studies, and the future of this technique. Filling this need, Leveraging the Wisdom of the Crowd in Software Testing shows you how to leverage the wisdom of the crowd in your software testing process. Its comprehensive coverage includes the history of crowdsourcing and crowdsourced testing, implementation practices, and future trends. The book discusses best practices in implementation-explaining what, when, and how to crowdsource in a testing effort. It also includes case studies that illustrate how both product and service companies have successfully applied crowdsourcing in their testing programs. Explaining how to use the combined advantages of crowdsourcing and cloud computing for software testing, the book examines various engagement models in which you could implement crowdsourced testing. It addresses effective defect management in crowdsourced testing and considers both the business and engineering aspects of crowdsourced testing. The book explores the challenges, limitations, and situations when crowdsourced testing will not work and provides powerful best practices for mitigating the constraints and challenges, including how to build a crowdsourcing platform to test software products. Covering career opportunities for crowd testers, the book concludes by taking a look at the need to build a crowdsourced testing ecosystem, who the players of such an ecosystem would be, and who would need to champion such an effort.


Crowdsourcing and Knowledge Management in Contemporary Business Environments

Crowdsourcing and Knowledge Management in Contemporary Business Environments

Author: Lenart-Gansiniec, Regina

Publisher: IGI Global

Published: 2018-08-17

Total Pages: 339

ISBN-13: 1522542019

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In an era of an economy based on knowledge and Web 2.0 technology, knowledge is the foundation for improving the decision-making processes and relations between people both in and outside of an organization. Providing new and unique sources of knowledge outside organizations enables innovation and shapes competitive advantage. Crowdsourcing and Knowledge Management in Contemporary Business Environments is a collection of innovative research on the methods and applications of crowdsourcing in collaboration, idea implementation, and organizational development. Highlighting a range of topics including data analytics, crowd computing, and open innovation, this book is ideally designed for business managers, business professionals, business and social researchers, graduate-level students, and academicians seeking current research on the mechanisms of knowledge management in crowdsourcing.


Taking [A]part

Taking [A]part

Author: John McCarthy

Publisher: MIT Press

Published: 2024-07-02

Total Pages: 202

ISBN-13: 0262552590

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A critical inquiry into the value and experience of participation in design research. In Taking [A]part, John McCarthy and Peter Wright consider a series of boundary-pushing research projects in human-computer interaction (HCI) in which the design of digital technology is used to inquire into participative experience. McCarthy and Wright view all of these projects—which range from the public and performative to the private and interpersonal—through the critical lens of participation. Taking participation, in all its variety, as the generative and critical concept allows them to examine the projects as a part of a coherent, responsive movement, allied with other emerging movements in DIY culture and participatory art. Their investigation leads them to rethink such traditional HCI categories as designer and user, maker and developer, researcher and participant, characterizing these relationships instead as mutually responsive and dialogical. McCarthy and Wright explore four genres of participation—understanding the other, building relationships, belonging in community, and participating in publics—and they examine participatory projects that exemplify each genre. These include the Humanaquarium, a participatory musical performance; the Personhood project, in which a researcher and a couple explored the experience of living with dementia; the Prayer Companion project, which developed a technology to inform the prayer life of cloistered nuns; and the development of social media to support participatory publics in settings that range from reality game show fans to on-line deliberative democracies.


Managing and Using Information Systems

Managing and Using Information Systems

Author: Keri E. Pearlson

Publisher: John Wiley & Sons

Published: 2024-01-11

Total Pages: 370

ISBN-13: 1394215444

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Provides the knowledge and insights necessary to contribute to the Information Systems decision-making process Managing & Using Information Systems: A Strategic Approach delivers a solid knowledgebase of basic concepts to help MBA students and general business managers alike become informed, competent participants in Information Systems (IS) decisions. Now in its eighth edition, this fully up-to-date textbook explains the fundamental principles and practices required to use and manage information while illustrating how information systems can create or obstruct opportunities — and even propel digital transformations within a wide range of organizations. Drawing from their expertise in both academia and industry, the authors discuss the business and design processes relevant to IS while presenting a basic framework that connects business strategy, IS strategy, and organizational strategy. Step by step, readers are guided through each essential aspect of Information Systems, from fundamental information architecture and infrastructure to cyber security, Artificial Intelligence (AI), business analytics, project management, platform and IS governance, IS sourcing, and more. Detailed chapters contain mini-cases, full-length case studies, discussion topics, review questions, supplemental readings, and topic-specific managerial concerns that provide insights into real-world IS issues. Managing & Using Information Systems: A Strategic Approach, Eighth Edition, is an excellent textbook for advanced undergraduate and MBA-level courses on IS concepts and managerial approaches to leveraging emerging information technologies.


Developing with Google App Engine

Developing with Google App Engine

Author: Eugene Ciurana

Publisher: Apress

Published: 2009-03-22

Total Pages: 166

ISBN-13: 1430218320

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Developing with Google App Engine introduces development with Google App Engine, a platform that provides developers and users with infrastructure Google itself uses to develop and deploy massively scalable applications. Introduction to concepts Development with App Engine Deployment into App Engine


Crowd-Powered Mobile Computing and Smart Things

Crowd-Powered Mobile Computing and Smart Things

Author: Seng W. Loke

Publisher: Springer

Published: 2017-02-27

Total Pages: 71

ISBN-13: 3319544365

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This SpringerBrief provides a synergistic overview of technology trends by emphasizing five linked perspectives: crowd+cloud machines, extreme cooperation with smart things, scalable context-awareness, drone services for mobile crowds and social links in mobile crowds. The authors also highlight issues and challenges at the intersection of these trends. Topics covered include cloud computing, Internet of Things, mobile and wearable computing, crowd computing, the culture of thing sharing, collective computing, and swarm dynamics. The brief is a useful resource and a starting point for researchers, students or anyone interested in the contemporary computing landscape.


Troubled Water

Troubled Water

Author: Gregory A. Freeman

Publisher: St. Martin's Press

Published: 2009-09-15

Total Pages: 280

ISBN-13: 0230100546

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The gripping account of the riot aboard the USS Kitty Hawk—and the first mutiny in U.S. Naval history In 1972, the United States was embroiled in an unpopular war in Vietnam, and the USS Kitty Hawk was headed to her station in the Gulf of Tonkin. Its five thousand men, cooped up for the longest at-sea tour of the war, rioted--or, as Troubled Water suggests, mutinied. Disturbingly, the lines were drawn racially, black against white. By the time order was restored, careers were in tatters. Although the incident became a turning point for race relations in the Navy, this story remained buried within U.S. Navy archives for decades. With action pulled straight from a high-seas thriller, Gregory A. Freeman uses eyewitness accounts and a careful and unprecedented examination of the navy's records to refute the official story of the incident, make a convincing case for the U.S. navy's first mutiny, and shed new light on this seminal event in American history.


Cloud Computing and Big Data

Cloud Computing and Big Data

Author: C. Catlett

Publisher: IOS Press

Published: 2013-10-22

Total Pages: 260

ISBN-13: 161499322X

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Cloud computing offers many advantages to researchers and engineers who need access to high performance computing facilities for solving particular compute-intensive and/or large-scale problems, but whose overall high performance computing (HPC) needs do not justify the acquisition and operation of dedicated HPC facilities. There are, however, a number of fundamental problems which must be addressed, such as the limitations imposed by accessibility, security and communication speed, before these advantages can be exploited to the full. This book presents 14 contributions selected from the International Research Workshop on Advanced High Performance Computing Systems, held in Cetraro, Italy, in June 2012. The papers are arranged in three chapters. Chapter 1 includes five papers on cloud infrastructures, while Chapter 2 discusses cloud applications. The third chapter in the book deals with big data, which is nothing new – large scientific organizations have been collecting large amounts of data for decades – but what is new is that the focus has now broadened to include sectors such as business analytics, financial analyses, Internet service providers, oil and gas, medicine, automotive and a host of others. This book will be of interest to all those whose work involves them with aspects of cloud computing and big data applications.