Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data

Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data

Author: Arthur L. Craigmill

Publisher: Wiley-Blackwell

Published: 2006-01-18

Total Pages: 1935

ISBN-13: 9780813813493

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The use of therapeutic and antimicrobial agents to prevent, to control, and to eradicate disease in herd animals has without question revolutionized food animal production capacity. But how much of a good thing is too much? 20th century advances in disease diagnosis and treatment have led to 21st century concerns about the health risks posed to consumers when the animals they consume have been exposed to antimicrobials, therapeutic drugs, pesticides and other environmental contaminants. The Food Animal Residue Avoidance Databank provides the pharmacologic data that veterinarians and producers need to screen animals that have been exposed to chemicals and to ensure that dangerously contaminated tissues of food-producing animals do not enter the human food chain. Established only twenty years ago under the auspices of the USDA, FARAD is an international venture that brings together and collates information on applications of pharmacokinetic principles to drug and chemical residue avoidance--information that previously has been spread throughout the literature. Now, the Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data brings together in a single source all the most current information on chemical residues in food animals, and provides easy access and numerous tables that offer essential pharmacokinetic data for chemicals in serum, plasma, blood, or in other matrices. This updated one-of-a-kind volume also features additional data on laboratory rodents, dogs, cats, and horses to facilitate broader interspecies extrapolations. This easy-to-use and newly-updated publication is the essential reference on the subject and belongs in the library of veterinarians, toxicologists, pharmacologists, animal scientists, food hygienists, and regulatory personnel involved in human food safety.


Comparative Pharmacokinetics

Comparative Pharmacokinetics

Author: Jim E. Riviere

Publisher: John Wiley & Sons

Published: 2011-01-14

Total Pages: 456

ISBN-13: 0470959886

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Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.


Veterinary Pharmacology and Therapeutics

Veterinary Pharmacology and Therapeutics

Author: Jim E. Riviere

Publisher: John Wiley & Sons

Published: 2017-11-29

Total Pages: 1552

ISBN-13: 1118855779

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Veterinary Pharmacology and Therapeutics, Tenth Edition is a fully updated and revised version of the gold-standard reference on the use of drug therapy in all major veterinary species. Provides current, detailed information on using drug therapies in all major domestic animal species Organized logically by drug class and treatment indication, with exhaustive information on the rational use of drugs in veterinary medicine Includes extensive tables of pharmacokinetic data, products available, and dosage regimens Adds new chapters on pharmaceutics, ophthalmic pharmacology, food animal pharmacology, and aquatic animal pharmacology Includes access to a companion website with the figures from the book in PowerPoint


Goat Medicine

Goat Medicine

Author: Mary C. Smith

Publisher: John Wiley & Sons

Published: 2011-11-16

Total Pages: 886

ISBN-13: 1119949521

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Fully revised and expanded, Goat Medicine, Second Edition includes discussions on new diseases ranging from bovine spongiform encephalopathy to floppy kid disease as well as major updates on important diseases such as scrapie, mycoplasmosis, paratuberculosis, and urolithiasis. Information has also been added on management of transgenic goats and organic goat production. The text begins by outlining fundamentals of goat practice and moves on to systems-based coverage of the goat. Each chapter provides clinical anatomy and physiology of every system alongside information on relevant clinical signs, differential diagnosis, and system-specific disease.


Nanotoxicology

Nanotoxicology

Author: Nancy A. Monteiro-Riviere

Publisher: CRC Press

Published: 2007-07-25

Total Pages: 452

ISBN-13: 1420045156

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Nanomaterials - structures with characteristic dimensions between 1 and 100 nm -exhibit a variety of unique and tunable chemical and physical properties that have made engineered nanoparticles central components in an array of emerging technologies. The use of nanotechnology is increasing; however its potential adverse effects on human health are n


Chemical Analysis of Antibiotic Residues in Food

Chemical Analysis of Antibiotic Residues in Food

Author: Jian Wang

Publisher: John Wiley & Sons

Published: 2011-11-29

Total Pages: 378

ISBN-13: 1118067193

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An insightful exploration of the key aspects concerning the chemical analysis of antibiotic residues in food The presence of excess residues from frequent antibiotic use in animals is not only illegal, but can pose serious health risks by contaminating products for human consumption such as meat and milk. Chemical Analysis of Antibiotic Residues in Food is a single-source reference for readers interested in the development of analytical methods for analyzing antibiotic residues in food. It covers themes that include quality assurance and quality control, antibiotic chemical properties, pharmacokinetics, metabolism, distribution, food safety regulations, and chemical analysis. In addition, the material presented includes background information valuable for understanding the choice of marker residue and target animal tissue to use for regulatory analysis. This comprehensive reference: Includes topics on general issues related to screening and confirmatory methods Presents updated information on food safety regulation based on routine screening and confirmatory methods, especially LC-MS Provides general guidance for method development, validation, and estimation of measurement uncertainty Chemical Analysis of Antibiotic Residues in Food is written and organized with a balance between practical use and theory to provide laboratories with a solid and reliable reference on antibiotic residue analysis. Thorough coverage elicits the latest scientific findings to assist the ongoing efforts toward refining analytical methods for producing safe foods of animal origin.


Strategies for Reducing Drug and Chemical Residues in Food Animals

Strategies for Reducing Drug and Chemical Residues in Food Animals

Author: Ronald E. Baynes

Publisher: John Wiley & Sons

Published: 2014-08-06

Total Pages: 340

ISBN-13: 1118872827

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Highlighting international approaches; the book details strategies to minimize contamination, residue monitoring programs, and classes of drugs and chemicals that pose contaminant risk in livestock. Focuses attention on drug and chemical residues in edible animal products Covers novel computational, statistical, and mathematical strategies for dealing with chemical exposures in food animals Details major drug classes used in food animal production and their residue risks Highlights efforts at harmonizing and the differences among areas like US, EU, Canada, Australia, South America, China, and Asia, where the issue of chemical exposures has significant impact on livestock products Ties veterinary clinical practice and the use of these drugs in food animals with regulatory standards and mitigation practices


Chemical Contaminants and Residues in Food

Chemical Contaminants and Residues in Food

Author: D Schrenk

Publisher: Elsevier

Published: 2012-08-23

Total Pages: 604

ISBN-13: 085709579X

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Chemical contaminants are a major concern for the food industry. Chemical contaminants and residues in food provides an essential guide to the main chemical contaminants, their health implications, the processes by which they contaminate food products, and methods for their detection and control.Part one focuses on risk assessment and analytical methods. Gas chromatography and mass spectroscopy techniques for the detection of chemical contaminants and residues are discussed, as are applications of HPLC-MS techniques and cell-based bioassays. Major chemical contaminants are then discussed in part two, including dioxins and polychlorinated biphenyls, veterinary drug and pesticide residues, heat-generated and non-thermally-produced toxicants, D- and cross-linked amino acids, mycotoxins and phycotoxins, and plant-derived contaminants. Finally, part three goes on to explore the contamination of specific foods. Chemical contamination of cereals, red meat, poultry and eggs are explored, along with contamination of finfish and marine molluscs.With its distinguished editor and international team of expert contributors, Chemical contaminants and residues in food is an invaluable tool for all industrial and academic researchers involved with food safety, from industry professionals responsible for producing safe food, to chemical analysts involved in testing the final products. - Provides an essential guide to the main chemical contaminants, their health implications, the processes by which they contaminate food products, and methods for their detection and control - Sections provide in-depth focus on risk assessment and analytical methods, major chemical contaminants, and the contamination of specific foods - Chemical contamination of cereals, red meat, poultry and eggs are explored, along with contamination of finfish and marine molluscs