A Curse in Darkness (The Thornheart Trials, Book 1)
A Curse in Darkness (The Thornheart Trials, Book 1)

Author: Sherilee Gray

Publisher: Sherilee Gray

Published: 2021-09-28

Total Pages: 410

ISBN-13: 0473580020

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Willow ​I once faced evil…and lost. With the fate of my family—and our magic—suddenly in my hands, I vow to protect them no matter what. But the coven trials have claimed many witches, and vanquishing malevolent spirits, while hunting a possessed hellhound on a killing spree, is far more than I bargained for. Now the hellhound’s domineering alpha is shadowing me. More beast than man, Warrick both tempts and terrifies. Still, I can’t resist our overwhelming attraction and when a twisted enemy makes their move and I’m faced with an impossible choice, I need him more than ever. But fortune is fickle, and in a world full of monsters, falling in love can be hazardous to your health—and your heart. The Thornheart Trials: Book 1: A Curse in Darkness Book 2: A Vow of Ruin Book 3: A Trial by Blood Keywords: romance, paranormal romance, witches, witch, witch romance, hellhound, hellhound shifter, Hell, occult, witchcraft, demons, demon hunter, angels, archangels, angels and demons, shifter, alpha male, bad boy hero, strong heroine, fated mates, tattooed hero, romantic suspense, action and adventure, shapeshifter, Urban fantasy, Thriller & Suspense, sagas, series, mystery, paranormal fantasy, dark romance, mystery thriller

T. R. I. A. L. S.
T. R. I. A. L. S.

Author: Chase Turner

Publisher:

Published: 2020-01-22

Total Pages:

ISBN-13: 9781734531909

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Can you imagine waking up tomorrow and having no anxiety at work, finances, marriage or health? Nearly every person deals with anxiety and everyone deals with stress. There are many reasons for this epidemic, but anxiety is a result of how we handle the stress that we and others place in our lives. One of the primary causes of stress is comparative living, which comes as a result of trying to be "normal". The T.R.I.A.L.S. method has been developed to help everyone in their daily routine and relationships so stress can be minimal, and anxiety can be avoided. This workbook is designed to help individuals in their daily walk to develop relationships in a way that will increase communication and decrease stress and anxiety. There is space for making goals and plans for carrying them out.

The Prevention and Treatment of Missing Data in Clinical Trials
The Prevention and Treatment of Missing Data in Clinical Trials

Author: National Research Council

Publisher: National Academies Press

Published: 2010-12-21

Total Pages: 163

ISBN-13: 030918651X

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Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

A Practical Guide to Managing Clinical Trials
A Practical Guide to Managing Clinical Trials

Author: JoAnn Pfeiffer

Publisher: CRC Press

Published: 2017-05-18

Total Pages: 292

ISBN-13: 1315299771

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A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site set-up, subject recruitment, study visits, and to study close-out. Topics include staff roles/responsibilities/training, budget and contract review and management, subject study visits, data and document management, event reporting, research ethics, audits and inspections, consent processes, IRB, FDA regulations, and good clinical practices. Each chapter concludes with a review of key points and knowledge application. Unique to this book is "A View from India," a chapter-by-chapter comparison of clinical trial practices in India versus the U.S. Throughout the book and in Chapter 10, readers will glimpse some of the challenges and opportunities in the emerging and growing market of Indian clinical trials.

Book of the End - Great Trials and Tribulations
Book of the End - Great Trials and Tribulations

Author:

Publisher: Darussalam

Published: 2006

Total Pages: 28

ISBN-13: 9789960971506

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Like everything, the present universe will also come to an end, and it is a part of our faith to believe in the Last Day. The signs of the Day of Judgment have been foretold by our Prophet (S). Ibn Kathir has collected all the prophesies of the Prophet (S) in his book Al-Bidaayah wan-Nihaayah. In this volume, we have presented from them the signs of the Hour and the events that are yet to take place, although mentioning very few examples of those prophesies that have already been realized.

Shadowspell Academy: The Culling Trials
Shadowspell Academy: The Culling Trials

Author: Shannon Mayer

Publisher: Sky Pony

Published: 2019-11-05

Total Pages: 0

ISBN-13: 9781510755109

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A Teenage Girl Torn from her Family Must Survive a Series of Deadly Trials to Earn her Place in a Dangerous School of Magic, from Bestselling Authors K.F. Breene and Shannon Mayer You don't choose The Academy. The Academy chooses you. I had no idea how those words would change my life, until the day the most dangerous man I’ve ever met waltzed onto my farm and left us a death sentence. My younger brother has been chosen for The Academy: the prestigious, secret school of magic hidden within the folds of our mundane world. A place where there’s no guarantee you’ll make it out alive. If he doesn't go, our entire family will be killed. It’s the same invitation my older brother received three years ago—and he never came home. The Academy has already killed one sibling, and I’ll be damned if they take another. So I do the only thing an older sister can: chop off my hair, strap on two bras to flatten the girls, and take my brother’s place. Magic and monsters are real. Assassins are coming for me, and the dead are prone to rise. What’s a girl faking it as a boy supposed to do? Being accepted into an elite school of magic, monsters, and assassins was not my idea of higher education. But here I am, fighting my way through the deadly physical and mental tests of the Culling Trials to claim my right to be taught. In a cutthroat world where no one is as they seem, the golden rule is simple: Trust no one. The Academy tells us we should just look out for ourselves. That we should leave the fallen behind and ask no questions. Not on my watch.

The Princess Trials
The Princess Trials

Author: Cordelia K. Castel

Publisher:

Published: 2020-05-02

Total Pages: 504

ISBN-13:

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Thirty young women. A handsome prince. A battle to the death Water is scarce. Deserts have taken over the land. Nuclear war has devastated humanity. Humans live in walled super cities to keep out the irradiated. The land that was formerly known as America is divided into kingdoms ruled by royal elites.Born into the lowest Echelon of the Kingdom of Phangloria, sixteen-year-old Zea Calico faces a life of hunger, thirst, and toil. The only way out of this drudgery is revolution, and Zea is desperate to help the cause. When the palace calls for candidates to compete to marry Prince Kevon, Zea joins the Princess Trials to search the palace for weaknesses. The trials should be a fairytale of sumptuous meals, ballgowns, and romance, but one misplaced word causes Zea to attract the Prince's attention. When Zea uncovers the man beneath Prince Kevon's public facade, she is at risk of falling in love and losing sight of her mission. But the televised beauty pageant turns deadly, and Zea must fight for survival.Perfect for fans of The Hunger Games and The Selection, this exciting tale of courage, intrigue, and betrayal will have you turning pages.

The Blood Trials
The Blood Trials

Author: N. E. Davenport

Publisher: HarperCollins

Published: 2022-04-05

Total Pages: 429

ISBN-13: 0063058502

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Blending fantasy and science fiction, N. E. Davenport’s fast-paced, action-packed debut kicks off a duology of loyalty and rebellion, in which a young Black woman must survive deadly trials in a racist and misogynistic society to become an elite warrior. It’s all about blood. The blood spilled between the Republic of Mareen and the armies of the Blood Emperor long ago. The blood gifts of Mareen’s deadliest enemies. The blood that runs through the elite War Houses of Mareen, the rulers of the Tribunal dedicated to keeping the republic alive. The blood of the former Legatus, Verne Amari, murdered. For his granddaughter, Ikenna, the only thing steady in her life was the man who had saved Mareen. The man who had trained her in secret, not just in martial skills, but in harnessing the blood gift that coursed through her. Who trained her to keep that a secret. But now there are too many secrets, and with her grandfather assassinated, Ikenna knows two things: that only someone on the Tribunal could have ordered his death, and that only a Praetorian Guard could have carried out that order. Bent on revenge as much as discovering the truth, Ikenna pledges herself to the Praetorian Trials—a brutal initiation that only a quarter of the aspirants survive. She subjects herself to the racism directed against her half-Khanaian heritage and the misogyny of a society that cherishes progeny over prodigy, all while hiding a power that—if found out—would subject her to execution…or worse. Ikenna is willing to risk it all because she needs to find out who murdered her grandfather…and then she needs to kill them. Mareen has been at peace for a long time… Ikenna joining the Praetorians is about to change all that. Magic and technology converge in the first part of this stunning debut duology, where loyalty to oneself—and one’s blood—is more important than anything.

The Poison Trials
The Poison Trials

Author: Alisha Rankin

Publisher: University of Chicago Press

Published: 2021-01-01

Total Pages: 0

ISBN-13: 9780226744858

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In 1524, Pope Clement VII gave two condemned criminals to his physician to test a promising new antidote. After each convict ate a marzipan cake poisoned with deadly aconite, one of them received the antidote, and lived—the other died in agony. In sixteenth-century Europe, this and more than a dozen other accounts of poison trials were committed to writing. Alisha Rankin tells their little-known story. At a time when poison was widely feared, the urgent need for effective cures provoked intense excitement about new drugs. As doctors created, performed, and evaluated poison trials, they devoted careful attention to method, wrote detailed experimental reports, and engaged with the problem of using human subjects for fatal tests. In reconstructing this history, Rankin reveals how the antidote trials generated extensive engagement with “experimental thinking” long before the great experimental boom of the seventeenth century and investigates how competition with lower-class healers spurred on this trend. The Poison Trials sheds welcome and timely light on the intertwined nature of medical innovations, professional rivalries, and political power.