This two-volume work provides an overview on various state of the art experimental and statistical methods, modeling approaches and software tools that are available to generate, integrate and analyze multi-omics datasets in order to detect biomarkers, genetic markers and potential causal genes for improved animal production and health. The book will contain online resources where additional data and programs can be accessed. Some chapters also come with computer programming codes and example datasets to provide readers hands-on (computer) exercises. This first volume presents the basic principles and concepts of systems biology with theoretical foundations including genetic, co-expression and metabolic networks. It will introduce to multi omics components of systems biology from genomics, through transcriptomics, proteomics to metabolomics. In addition it will highlight statistical methods and (bioinformatic) tools available to model and analyse these data sets along with phenotypes in animal production and health. This book is suitable for both students and teachers in animal sciences and veterinary medicine as well as to researchers in this discipline.
This two-volume work provides an overview on various state of the art experimental and statistical methods, modeling approaches and software tools that are available to generate, integrate and analyze multi-omics datasets in order to detect biomarkers, genetic markers and potential causal genes for improved animal production and health. The book will contain online resources where additional data and programs can be accessed. Some chapters also come with computer programming codes and example datasets to provide readers hands-on (computer) exercises. This second volume deals with integrated modeling and analyses of multi-omics datasets from theoretical and computational approaches and presents their applications in animal production and health as well as veterinary medicine to improve diagnosis, prevention and treatment of animal diseases. This book is suitable for both students and teachers in animal sciences and veterinary medicine as well as to researchers in this discipline.
In recent years there has been a huge rise in interdisciplinary and multidisciplinary research in animal sciences which has accelerated improvements in animal welfare. Down to earth and practical, this book gives guidance on how cross-disciplinary research can advance animal welfare. The aim of the book is to help researchers and graduate animal science students to understand how to advance animal welfare through the integration of disciplines.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.
Biotechnology in Healthcare, Technologies and Innovations, Volume One presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Sections cover 3D printing, tissue engineering, synthetic biology, nano-biotechnology, omics, precision medicine, gene therapy, vaccine development, predictive healthcare, entrepreneurship, financing, business models, product development and marketing in the sector. This is a valuable source for biotechnologists, bioinformaticians, clinicians and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare. - Presents the progress and innovations that biotechnology has accomplished in the field of healthcare - Discusses the impact of healthcare biotechnology in global economics and business prospects - Explains how biotechnology revolutionizes future healthcare approaches
Agriculture in the 21st century will need considerable modification to remain both productive and sustainable. Greater production is needed to meet the needs of our still-growing populations and to combat hunger and poverty. Declines in soil health and the pollution of water sources are making many of our production systems less tenable. These adverse trends are exacerbated more and more by the impacts of climate change. There are, fortunately, alternative methods available for agricultural practice that can countervail these constraints. Biological Approaches to Regenerative Soil Systems brings together the work of both researchers and practitioners to map out better approaches to contemporary agriculture that draw upon both old and new knowledge. It presents the science that underlies more biologically driven strategies as well as contemporary innovative experiences in diverse parts of the world. Both accepted research and these varied experiences encourage confidence that these approaches, not relying primarily on the introduction of new varieties and on exogenous inputs, can succeed. This book updates and revises a preceding volume Biological Approaches to Sustainable Soil Systems published by CRC Press in 2006. So much has been learned and done on this subject in the past decade and a half that a second edition was warranted. For instance, the first edition was published, knowledge about plant-soil microbiomes, which are a frequent focus in this book, has mushroomed. Because sustainability is a broad term and an end-state, the editors preferred to assemble expertise regarding regenerative agriculture, which is concerned with the means for achieving sustainability. The concept of regenerative soil systems, entities that are more complex and multifaceted than "soil" alone, also incorporates a concern with having more resilient agricultural systems, ones that are better able to cope with the multiple stresses of climate change that are foreseen for the decades ahead. The book’s chapters representing a wide range of disciplines were contributed by 84 scientists and practitioners from 20 countries. Although they come from persons with in-depth knowledge of their respective fields, the chapters are written to be accessible to readers who are not trained in the specialized subjects. Taken together, the chapters provide students, researchers, practitioners, planners, and policy makers with a comprehensive understanding of both the science and the steps needed to regenerate and sustain soil systems around the world for the long-term benefit of humankind and the environment.
This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field
