Handbook of Systems Biology

Handbook of Systems Biology

Author: Marian Walhout

Publisher: Academic Press

Published: 2012-12-31

Total Pages: 553

ISBN-13: 012385945X

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This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. - 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards - Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines - Includes the latest research developments in human and animal models to assist with translational research - Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers


Epigenetics and Systems Biology

Epigenetics and Systems Biology

Author: Leonie Ringrose

Publisher: Academic Press

Published: 2017-04-25

Total Pages: 287

ISBN-13: 0128030763

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Epigenetics and Systems Biology highlights the need for collaboration between experiments and theoretical modeling that is required for successful application of systems biology in epigenetics studies. This book breaks down the obstacles which exist between systems biology and epigenetics researchers due to information barriers and segmented research, giving real-life examples of successful combinations of systems biology and epigenetics experiments. Each section covers one type of modeling and one set of epigenetic questions on which said models have been successfully applied. In addition, the book highlights how modeling and systems biology relate to studies of RNA, DNA, and genome instability, mechanisms of DNA damage signaling and repair, and the effect of the environment on genome stability. - Presents original research in a wider perspective to reveal potential for synergies between the two fields of study - Provides the latest experiments in primary literature for the modeling audience - Includes chapters written by experts in systems biology and epigenetics who have vast experience studying clinical applications


MCAT Biology II by MCAT KING

MCAT Biology II by MCAT KING

Author: Noble Zaghi

Publisher: MCAT KING | Noble Academy Center

Published: 2021-01-12

Total Pages: 276

ISBN-13: 9781733990615

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The MCAT Biology II is part of a series of Test Prep books by MCAT KING that specifically designed for self-motivated self-study students who are seeking significant score improvement on the Medical School Admission Test. It is simple, smart, and remarkably effective. Whether you are new to the MCAT or have been studying for a while, you will find invaluable benefit in the MCAT KING's teachings, strategies, drills, and solutions. Packed with smart advice presented from the MCAT perspective, The MCAT King Test Prep Book series is a must for Pre-Med students preparing for the test.


Systems Biology

Systems Biology

Author: Bernhard Ø. Palsson

Publisher: Cambridge University Press

Published: 2006-01-16

Total Pages: 287

ISBN-13: 1139448943

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Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This textbook, devoted to systems biology, describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites are some knowledge of linear algebra and biochemistry. Though the links between the mathematical ideas and biological processes are made clear, the book reflects the irreversible trend of increasing mathematical content in biology education. Therefore to assist both teacher and student, in an associated website Palsson provides problem sets, projects and Powerpoint slides, and keeps the presentation in the book concrete with illustrative material and experimental results.


Systems Biology

Systems Biology

Author: Bernhard Palsson

Publisher: Cambridge University Press

Published: 2015-01-26

Total Pages: 551

ISBN-13: 1107038855

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The first comprehensive single-authored textbook on genome-scale models and the bottom-up approach to systems biology.


Cancer Systems Biology

Cancer Systems Biology

Author: Edwin Wang

Publisher: CRC Press

Published: 2010-05-04

Total Pages: 458

ISBN-13: 1439811865

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The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorgenesis, cancer research is enjoying a series of new discoveries and biological insights. Unique in its dualistic approach, this book introduces the concepts and theories of systems biology and their applications in cancer research. It presents basic cancer biology and cutting-edge topics of cancer research for computational biologists alongside systems biology analysis tools for experimental biologists.


Computational Systems Biology

Computational Systems Biology

Author: Andres Kriete

Publisher: Academic Press

Published: 2013-11-26

Total Pages: 549

ISBN-13: 0124059384

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This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.


Systems and Synthetic Biology

Systems and Synthetic Biology

Author: Vikram Singh

Publisher: Springer

Published: 2014-12-15

Total Pages: 383

ISBN-13: 9401795142

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This textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section will deal with systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section deals with the engineering concepts, design strategies of the biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell will be described. Finally, the book will offer expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists.


Evolutionary Systems Biology

Evolutionary Systems Biology

Author: Anton Crombach

Publisher: Springer Nature

Published: 2021-08-05

Total Pages: 299

ISBN-13: 3030717372

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This new edition captures the advances made in the field of evolutionary systems biology since the publication of the first edition. The first edition focused on laying the foundations of evolutionary systems biology as an interdisciplinary field, where a way of thinking and asking questions is combined with a wide variety of tools, both experimental and theoretical/computational. Since publication of the first edition, evolutionary systems biology is now a well-known term describing this growing field. The new edition provides an overview of the current status and future developments of this interdisciplinary field. Chapters highlight several key achievements from the last decade and outline exciting new developments, including an understanding of the interplay between complexity and predictability in evolutionary systems, new viewpoints and methods to study organisms in evolving populations at the level of the genome, gene regulatory network, and metabolic network, and better analysis and modeling techniques that will open new avenues of scientific inquiry.