Synthetic Pyrethroid Insecticides: Structures and Properties

Synthetic Pyrethroid Insecticides: Structures and Properties

Author: Klaus Naumann

Publisher: Springer

Published: 2014-08-23

Total Pages: 244

ISBN-13: 9783642748516

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The idea of Volums 4 and 5 of this series is a combination of a very condensed but broad review, handbook and textbook on most of the theoretical and practical aspects of pyrethroids of interest to chemists, biologists, pharmacologists, toxicologists and other people involved in insecticidal research, development, ecotoxicolo gy, application, patenting and commercialization of pyrethroids, as seen from a point of view of an industrial chemist once actively in volved in pyrethroid research. In order to provide a mode1 data base for testing quantitative structure activity relationships, the unique wealth of the numerous and diverse biological data dispersed in the literature is listed in about 110 tables, put in relation to each other and other standard compounds, together with many structural formulas of the com pounds involved. A number of data are published for the first time. Some of the more important reeent QSAR-studies are briefly acknowledged. Conformational aspects of bioactive pyrethroids are discussed (from synthesis, QSAR, X-ray); some of the X-ray derived conformations are published for the first time. The molecular basis of pyrethroid biological action is taken into consideration as intensively as possible. Stereochemical aspects are considered wherever they are involved in synthesis, biological activity, mode of action, metabolism (Vol. 4), and particularly in the complex problems in the production and relation of iso merically enriched trade products (Vol. 5). Since pyrethroid research is now, in manyaspeets, a finished chapter of applied research, a historieal treatment of the course of inventions is given (inventions, patent priorities).


Pyrethroid Insecticides

Pyrethroid Insecticides

Author: Ethel Eljarrat

Publisher: Springer Nature

Published: 2020-08-04

Total Pages: 317

ISBN-13: 3030556964

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This book reviews the latest developments concerning the analysis, fate, behaviour and toxicity of pyrethroid insecticides. Over the last few decades, pyrethroid insecticides have increasingly replaced organochlorine pesticides due to their relatively lower mammalian toxicity, selective insecticide activity and lower environmental persistence. They represent 25% of global sales of insecticides, and are considered to be “safe” since they are converted to non-toxic metabolites by oxidative metabolism in fish and by hydrolysis in mammals. However, recent studies have demonstrated their environmental ubiquity, their bioaccumulation and their toxicity in various aquatic and terrestrial organisms, and even in humans. Featuring contributions by leading experts, the book discusses the physico-chemical properties and uses of pyrethroid insecticides; the latest chemical analytical methods; their occurrence in the environment, biota and food; and their isomeric and enantiomeric behaviour. It particularly highlights the toxicological effects and human exposure to pyrethroid insecticides, and also offers insights into the effects of the salmon industry on the marine environment with a case study of sea lice treatment using pyrethroids. This comprehensive book is a valuable source of information for environmental scientists, policymakers and producers interested in issues related to pyrethroid insecticides.


Residue Reviews/Rückstandsberichte

Residue Reviews/Rückstandsberichte

Author: Francis A. Gunther

Publisher: Springer

Published: 1971-04-06

Total Pages: 169

ISBN-13: 9781461584605

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That residues of pesticide and other "foreign" chemicals in food stuffs are of concern to everyone everywhere is amply attested by the reception accorded previous volumes of "Residue Reviews" and by the gratifying enthusiasm, sincerity, and efforts shown by all the in dividuals from whom manuscripts have been solicited. Despite much propaganda to the contrary, there can never be any serious question that pest-control chemicals and food-additive chemicals are essential to adequate food production, manufacture, marketing, and storage, yet without continuing surveillance and intelligent control some of those that persist in our foodstuffs could at times conceivably endanger the public health. Ensuring safety-in-use of these many chemicals is a dynamic challenge, for established ones are continually being dis placed by newly developed ones more acceptable to food technologists, pharmacologists, taxicologists, and changing pest-control requirements in progressive food-producing economies. These matters are of genuine concern to increasing numbers of governmental agencies and legislative bodies around the world, for some of these chemicals have resulted in a few mishaps from improper use. Adequate safety-in-use evaluations of any of these chemicals per sisting into our foodstuffs are not simple matters, and they incorporate the considered judgments of many individuals highly trained in a variety of complex biological, chemical, food technological, medical, pharmacological, and toxicological disciplines.


Synthetic Pyrethroid Insecticides: Chemistry and Patents

Synthetic Pyrethroid Insecticides: Chemistry and Patents

Author: Klaus Naumann

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 404

ISBN-13: 364274852X

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Chemistry of Plant Protection continues the handbook "Chemie der Pflanzenschutz- und Schädlingsbekämpfungsmittel", edited by R. Wegler. Volumes 4 and 5 of the series provide the first complete and in depth overview of synthetic pyrethroid insecticides . Volume 5 presents a detailed survey of the numerous synthetic methods (270 reaction schemes) and of stereochemical aspects of trade products, and a compilation of almost every patent on pyrethroids (2700 references evaluated).


Synthetic Pyrethroid Insecticides: Structures and Properties

Synthetic Pyrethroid Insecticides: Structures and Properties

Author: Klaus Naumann

Publisher: Springer

Published: 1990-05-07

Total Pages: 278

ISBN-13: 9783540513131

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The idea of Volums 4 and 5 of this series is a combination of a very condensed but broad review, handbook and textbook on most of the theoretical and practical aspects of pyrethroids of interest to chemists, biologists, pharmacologists, toxicologists and other people involved in insecticidal research, development, ecotoxicolo gy, application, patenting and commercialization of pyrethroids, as seen from a point of view of an industrial chemist once actively in volved in pyrethroid research. In order to provide a mode1 data base for testing quantitative structure activity relationships, the unique wealth of the numerous and diverse biological data dispersed in the literature is listed in about 110 tables, put in relation to each other and other standard compounds, together with many structural formulas of the com pounds involved. A number of data are published for the first time. Some of the more important reeent QSAR-studies are briefly acknowledged. Conformational aspects of bioactive pyrethroids are discussed (from synthesis, QSAR, X-ray); some of the X-ray derived conformations are published for the first time. The molecular basis of pyrethroid biological action is taken into consideration as intensively as possible. Stereochemical aspects are considered wherever they are involved in synthesis, biological activity, mode of action, metabolism (Vol. 4), and particularly in the complex problems in the production and relation of iso merically enriched trade products (Vol. 5). Since pyrethroid research is now, in manyaspeets, a finished chapter of applied research, a historieal treatment of the course of inventions is given (inventions, patent priorities).


The Chemistry of Organophosphorus Pesticides

The Chemistry of Organophosphorus Pesticides

Author: Christa Fest

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 346

ISBN-13: 3642978762

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Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular reference to the relationship between structure and activity. The yearly production of these pesticides is now approaching 100,000 tons and thus offers an important example of applied research. If, however, one examines the historical develop ment of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus. The utility of the phosphoric acid pesticides is undisputed today - and furthermore it can be expected that they will solve many of the world's nutritional problems" yet from this field of applied research many paths are now leading back into basic research in chemistry, biochemistry, biology and toxicology etc. This clearly illustrates the problem of attempting to define pure and applied research. Originally, this book was conceived for students of chemistry who, on completion of their study, were uncertain about the place of applied research in industry but it was soon clear that such material, when supplemented with further data, would serve as an introduction to the field of pesticidal phosphoric acid compounds for many technicians, officials and scientists who, in various authorities in agriculture, in chemical and biological research, are concerned with the problems of crop protection and more recently with questions of pollution of the environ ment.