Summarizing Biological Networks
Summarizing Biological Networks

Author: Sourav S. Bhowmick

Publisher: Springer

Published: 2017-04-17

Total Pages: 159

ISBN-13: 331954621X

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This book focuses on the data mining, systems biology, and bioinformatics computational methods that can be used to summarize biological networks. Specifically, it discusses an array of techniques related to biological network clustering, network summarization, and differential network analysis which enable readers to uncover the functional and topological organization hidden in a large biological network. The authors also examine crucial open research problems in this arena. Academics, researchers, and advanced-level students will find this book to be a comprehensive and exceptional resource for understanding computational techniques and their applications for a summary of biological networks.

Handbook on Biological Networks
Handbook on Biological Networks

Author: Stefano Boccaletti

Publisher: World Scientific

Published: 2010

Total Pages: 465

ISBN-13: 9812838791

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Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research ? the study of complex networks. In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology.

Analysis of Biological Networks
Analysis of Biological Networks

Author: Björn H. Junker

Publisher: John Wiley & Sons

Published: 2011-09-20

Total Pages: 278

ISBN-13: 1118209915

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An introduction to biological networks and methods for their analysis Analysis of Biological Networks is the first book of its kind to provide readers with a comprehensive introduction to the structural analysis of biological networks at the interface of biology and computer science. The book begins with a brief overview of biological networks and graph theory/graph algorithms and goes on to explore: global network properties, network centralities, network motifs, network clustering, Petri nets, signal transduction and gene regulation networks, protein interaction networks, metabolic networks, phylogenetic networks, ecological networks, and correlation networks. Analysis of Biological Networks is a self-contained introduction to this important research topic, assumes no expert knowledge in computer science or biology, and is accessible to professionals and students alike. Each chapter concludes with a summary of main points and with exercises for readers to test their understanding of the material presented. Additionally, an FTP site with links to author-provided data for the book is available for deeper study. This book is suitable as a resource for researchers in computer science, biology, bioinformatics, advanced biochemistry, and the life sciences, and also serves as an ideal reference text for graduate-level courses in bioinformatics and biological research.

Fundamentals Of Network Biology
Fundamentals Of Network Biology

Author: Wenjun Zhang

Publisher: World Scientific

Published: 2018-05-18

Total Pages: 568

ISBN-13: 1786345102

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As the first comprehensive title on network biology, this book covers a wide range of subjects including scientific fundamentals (graphs, networks, etc) of network biology, construction and analysis of biological networks, methods for identifying crucial nodes in biological networks, link prediction, flow analysis, network dynamics, evolution, simulation and control, ecological networks, social networks, molecular and cellular networks, network pharmacology and network toxicology, big data analytics, and more.Across 12 parts and 26 chapters, with Matlab codes provided for most models and algorithms, this self-contained title provides an in-depth and complete insight on network biology. It is a valuable read for high-level undergraduates and postgraduates in the areas of biology, ecology, environmental sciences, medical science, computational science, applied mathematics, and social science.

Biological Networks in Human Health and Disease
Biological Networks in Human Health and Disease

Author: Romana Ishrat

Publisher: Springer Nature

Published: 2023-10-13

Total Pages: 132

ISBN-13: 981994242X

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This book presents methods and tools of network biology and bioinformatics for understanding the disease dynamics and identification of drug targets. The initial section of chapters introduce the theoretical aspects followed by the different applications for construction and analysis of biological networks, methods for identifying crucial nodes in networks, and network dynamics. The book covers the latest advances in the network medicine, exploring the different types of biological networks, and their applications. It further reviews the role of R language in the network-based approaches that help in understanding biological systems and identifying biological functions. Towards the end, the book explores the recent developments and applications in machine learning and its potential for advancing network biology. Finally, the book elucidates a comprehensive yet a representative description of challenges associated with the understanding of disease dynamics using network biology. Given its scope, the book is intended for researchers and advanced postgraduate students of bioinformatics, computational biology, and medical sciences. ​

Database Systems for Advanced Applications
Database Systems for Advanced Applications

Author: Sang-goo Lee

Publisher: Springer

Published: 2012-04-05

Total Pages: 355

ISBN-13: 3642290353

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This two volume set LNCS 7238 and LNCS 7239 constitutes the refereed proceedings of the 17th International Conference on Database Systems for Advanced Applications, DASFAA 2012, held in Busan, South Korea, in April 2012. The 44 revised full papers and 8 short papers presented together with 2 invited keynote papers, 8 industrial papers, 8 demo presentations, 4 tutorials and 1 panel paper were carefully reviewed and selected from a total of 159 submissions. The topics covered are query processing and optimization, data semantics, XML and semi-structured data, data mining and knowledge discovery, privacy and anonymity, data management in the Web, graphs and data mining applications, temporal and spatial data, top-k and skyline query processing, information retrieval and recommendation, indexing and search systems, cloud computing and scalability, memory-based query processing, semantic and decision support systems, social data, data mining.

Networks in Cell Biology
Networks in Cell Biology

Author: Mark Buchanan

Publisher: Cambridge University Press

Published: 2010-05-13

Total Pages: 282

ISBN-13: 0521882737

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Key introductory text for graduate students and researchers in physics, biology and biochemistry.

Systems Biology in Biotech & Pharma
Systems Biology in Biotech & Pharma

Author: Aleš Prokop

Publisher: Springer Science & Business Media

Published: 2012-01-05

Total Pages: 137

ISBN-13: 9400728492

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The US is currently well ahead of the rest of the world in the development and application of SB and its principles especially as they pertain to basic medical research and development. This lead is largely due to its earlier start in the academic arena. However, there is evidence of rapid development in both the UK/EU and Japan, and the gap is narrowing, particularly in the UK. From an industrial point of view, the Pharmaceutical Industry based in the US and UK can capitalize on these opportunities and gain the benefits of this technology. Many educational institutions (particularly their medical divisions) at present are heavily business-oriented, realize that in this particular industrial environment, that every dollar counts.

Networks of Networks in Biology
Networks of Networks in Biology

Author: Narsis A. Kiani

Publisher: Cambridge University Press

Published: 2021-04-01

Total Pages: 215

ISBN-13: 1108690858

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Biological systems are extremely complex and have emergent properties that cannot be explained or even predicted by studying their individual parts in isolation. The reductionist approach, although successful in the early days of molecular biology, underestimates this complexity. As the amount of available data grows, so it will become increasingly important to be able to analyse and integrate these large data sets. This book introduces novel approaches and solutions to the Big Data problem in biomedicine, and presents new techniques in the field of graph theory for handling and processing multi-type large data sets. By discussing cutting-edge problems and techniques, researchers from a wide range of fields will be able to gain insights for exploiting big heterogonous data in the life sciences through the concept of 'network of networks'.

Biological Network Analysis
Biological Network Analysis

Author: Pietro Hiram Guzzi

Publisher: Elsevier

Published: 2020-05-11

Total Pages: 212

ISBN-13: 0128193514

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Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource. - Presents recent advances in biological network analysis, combining Graph Theory, Graph Analysis, and various network models - Discusses three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN) and Human Brain Connectomes - Includes a discussion of various graph theoretic and data analytics approaches