Molecular Biology of the Cell
Author:
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
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Proteins
Author: David Whitford
Publisher: John Wiley & Sons
Published: 2013-04-25
Total Pages: 544
ISBN-13: 1118685725
DOWNLOAD EBOOKProteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. Opening with a brief historical overview of the subject the book moves on to discuss the ‘building blocks’ of proteins and their respective chemical and physical properties. Later chapters explore experimental and computational methods of comparing proteins, methods of protein purification and protein folding and stability. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of Proteins.
Biology for AP ® Courses
Author: Julianne Zedalis
Publisher:
Published: 2017-10-16
Total Pages: 1923
ISBN-13: 9781947172401
DOWNLOAD EBOOKBiology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Plant Virology
Author: Roger Hull
Publisher: Academic Press
Published: 2013-10-31
Total Pages: 1119
ISBN-13: 0123848725
DOWNLOAD EBOOKThe seminal text Plant Virology is now in its fifth edition. It has been 10 years since the publication of the fourth edition, during which there has been an explosion of conceptual and factual advances. The fifth edition of Plant Virology updates and revises many details of the previous edition while retaining the important earlier results that constitute the field's conceptual foundation. Revamped art, along with fully updated references and increased focus on molecular biology, transgenic resistance, aphid transmission, and new, cutting-edge topics, bring the volume up to date and maintain its value as an essential reference for researchers and students in the field. - Thumbnail sketches of each genera and family groups - Genome maps of all genera for which they are known - Genetic engineered resistance strategies for virus disease control - Latest understanding of virus interactions with plants, including gene silencing - Interactions between viruses and insect, fungal, and nematode vectors - Contains over 300 full-color illustrations
Chemistry of Protein Conjugation and Cross-Linking
Author: Shan S. Wong
Publisher: CRC Press
Published: 1991-06-18
Total Pages: 360
ISBN-13: 9780849358869
DOWNLOAD EBOOKChemical cross-linking reagents have attained great practical use in industry as well as in basic research, and an understanding of their fundamental principles of reaction is paramount to their applications. With broad coverage of the development and application of these reagents, Chemistry of Protein Conjugation and Cross-Linking discusses the mechanism of reaction and allows you to put the theory into practice. The book offers an explanation of the underlying mechanism of chemical modification, surveys all the bifunctional reagents used in bioconjugation and cross-linking, and provides a review of practical applications of these reagents in various areas of biochemistry, molecular biology, biotechnology, nucleic acid chemistry, immunochemistry, and diagnostic and biomedical disciplines. It contains numerous examples and illustrations, plus step-by-step explanations to reaction procedures. It is an excellent introduction and a comprehensive reference about chemical modification.
Protein-Protein and Domain-Domain Interactions
Author: Pandjassarame Kangueane
Publisher: Springer
Published: 2018-02-16
Total Pages: 216
ISBN-13: 9811073473
DOWNLOAD EBOOKThis book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement in Bioinformatics and Bioinformation Discovery. The chapters provide current information pertaining to the types of protein-protein complexes (homodimers, heterodimers, multimer complexes) in context with various specific and sensitive biological functions. The significance of such complex formation in human biology in the light of molecular evolution is also highlighted using several examples. The chapters also describe recent advancements on the molecular principles of protein-protein interaction with reference to evolution towards target identification in drug discovery. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with the molecular interaction of proteins.
Extrasynaptic GABAA Receptors
Author: Adam C. Errington
Publisher: Springer
Published: 2014-09-22
Total Pages: 301
ISBN-13: 149391426X
DOWNLOAD EBOOKGABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.
Macromolecular Protein Complexes III: Structure and Function
Author: J. Robin Harris
Publisher: Springer Nature
Published: 2020-11-30
Total Pages: 580
ISBN-13: 3030589714
DOWNLOAD EBOOKThis book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few. The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Biochemistry of Collagen
Author: Gopalasamudram Ramachandran
Publisher: Springer Science & Business Media
Published: 2013-06-29
Total Pages: 546
ISBN-13: 1475746024
DOWNLOAD EBOOKCollagen is a fascinating protein not only because of its ubiquitous occurrence in multicellular animals, but also because of its unique chemi cal structure. As the predominant constituent in bone, cartilage, skin, tendon, and tooth, it is not surprising that collagen is of interest to anatomists, biochemists, biomedical engineers, cell biologists, dermatolo gists, dental surgeons, leather chemists, orthopedic surgeons, physiologists, physicians, zoologists, and a host of others. This book was planned to provide an up-to-date comprehensive survey of all aspects of biochemistry of collagen. The recent discovery of genetically distinct collagens with tissue specificity has opened a new era in collagen biochemistry, and Karl Piez discusses this in the opening chapter on primary structure. In the next chapter, Ramachandran and Rama krishnan deal with the molecular structure of collagen, placing special emphasis on the conformational aspects of its polypeptide chains. Follow ing the consideration of primary and secondary structure of collagen, the three-dimensional arrangement of collagen molecules in the fibrils is covered by Miller in Chapter 3. Collagen is generally in the insoluble state in the living organism due to the cross-linking of individual molecules, and Tanzer describes the various aspects of this cross-linkage in Chapter 4. The biosynthesis of collagen is discussed in depth by Prockop and his colleagues.
Basic Sciences in Ophthalmology
Author: Josef Flammer
Publisher: Springer Science & Business Media
Published: 2013-02-19
Total Pages: 253
ISBN-13: 3642322611
DOWNLOAD EBOOKBasic Sciences in Ophthalmology aims to link clinical ophthalmology directly to its basic science roots. This first volume describes the physics and chemistry required for a sound understanding of modern ophthalmology. The book opens with an extensive discussion of the interaction of light with matter and the way in which light is used in ophthalmic examinations and treatments. After describing traditional methods of imaging, particular emphasis is placed on modern instrumentation such as OCT. The interaction between light and tissues in different types of laser treatment is also addressed. The chemistry section focuses on compounds particularly relevant to the eye, such as oxygen and water. The origin and consequences of oxidative stress are reviewed, and the physical behavior of chemical compounds in the eye is explained. Understanding is facilitated through the use of many examples taken from the field of ophthalmology. The text is complemented by about 450 figures.
