STEM: Learning to Walk is an textbook to engage learners and teachers with an different mode of thinking. That the learner is based on fluency and skill rather than intellect. That the objective of learning is rote memorization. With the understanding that rote memorization breeds familiarity with complex subjects and intellectual theories. That differential is possible and an very real objective for curriculum designers like Jason Changkyu Kim, Purister Publishing and Outsourcing.
This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.
Provides structural engineers with the knowledge and practical tools needed to perform structural designs for wind that incorporate major technological, conceptual, analytical and computational advances achieved in the last two decades. With clear explanations and documentation of the concepts, methods, algorithms, and software available for accounting for wind loads in structural design, it also describes the wind engineer's contributions in sufficient detail that they can be effectively scrutinized by the structural engineer in charge of the design. Wind Effects on Structures: Modern Structural Design for Wind, 4th Edition is organized in four sections. The first covers atmospheric flows, extreme wind speeds, and bluff body aerodynamics. The second examines the design of buildings, and includes chapters on aerodynamic loads; dynamic and effective wind-induced loads; wind effects with specified MRIs; low-rise buildings; tall buildings; and more. The third part is devoted to aeroelastic effects, and covers both fundamentals and applications. The last part considers other structures and special topics such as trussed frameworks; offshore structures; and tornado effects. Offering readers the knowledge and practical tools needed to develop structural designs for wind loadings, this book: Points out significant limitations in the design of buildings based on such techniques as the high-frequency force balance Discusses powerful algorithms, tools, and software needed for the effective design for wind, and provides numerous examples of application Discusses techniques applicable to structures other than buildings, including stacks and suspended-span bridges Features several appendices on Elements of Probability and Statistics; Peaks-over-Threshold Poisson-Process Procedure for Estimating Peaks; estimates of the WTC Towers’ Response to Wind and their shortcomings; and more Wind Effects on Structures: Modern Structural Design for Wind, 4th Edition is an excellent text for structural engineers, wind engineers, and structural engineering students and faculty.
Here is the ultimate guide to managing the most frequently encountered problem in the eye patient--dry eye disease. Dry Eye Disease: The Clinician's Guide to Management provides the latest diagnostic techniques, new approaches for classifying patients, and state-of-the-art, evidence-based medical and surgical treatments. The book opens with a review of the epidemiology and the multifactorial etiologies of dry eye disease. The authors guide the reader through taking a thorough patient history, conducting the diagnostic examination, and using clinical tests to make a confident evaluation of the severity of the disease. In their discussion of both medical and surgical techniques for management, the authors describe common treatments, such as punctal plugs, lid treatment, artificial tears, as well as innovative treatments including autologous serum drops, stem cell transplantation, and more. Highlights: Contributions from such internationally known experts as Shigeru Kinoshita, M. Reza Dana, Maurizio Rolando, Kazuo Tsubota, Kelly Nichols, Janine Smith, J. Daniel Nelson, Jay S. Pepose, Mark J. Mannis, Friedrich E. Kruse, Teruo Nishida, and others Thorough discussion of new and emerging diagnostic tests, including tear osmolarity, impression cytology, corneal permeability, and visual function, enables readers to expand and sharpen their techniques A bullet-point list of key points at the beginning of each chapter is ideal for rapidly reviewing important concepts Numerous tables organize the results of clinical surveys of common symptoms and factors associated with dry eye disease An extensive list of references, as well as a chapter covering online resources, helps the reader keep abreast of the newest research This is a timely reference for all ophthalmologists, optometrists, and trainees in these specialties. It is essential reading for practitioners treating contact lens wearers and refractive surgery patients, as well as patients with glaucoma and age-related macular degeneration.
Focuses on organisational goals and those of other stakeholders and society at large. This book provides an insight into the potential benefits and pitfalls, expectations and concerns of advancing a critical view of HRD in practice. It is intended for lecturers, students and practitioners who are aching for a critical analysis.
There are probably few people who do not dream of the good old times, when do ing science often meant fascination, excitement, even adventure. In our time, do ing science involves often technology and, perhaps, even business. But there are still niches where curiosity and fascination have their place. The subject of this book, technological as its title may sound, is one of the fortunate examples. It will report on lasers generating the coldest places in the Universe, and on table top laser microtools which can produce a heat "inferno" as it prevails in the interior of the Sun, or simulate, for specific plant cells, microgravity of the space around our plan et Earth. There will be some real surprises for the reader. The applications range from basic studies of the driving forces of cell division (and thus life) via genetic modification of cells (for example, for plant breeding) to medical applications such as blood cell analysis and finally in vitro fertilization. What are these instruments: laser microbeams and optical tweezers? Both are lasers coupled with a fluorescence microscope. The laser microbeam uses a pulsed ultraviolet laser. Light is focused, as well as possible, in space and time, in order to obtain extremely high light intensities - high enough to generate, for a very short instant, extremely hot spots which can be used to cut, fuse or perforate biological material.
Nanocolloids: A Meeting Point for Scientists and Technologists presents an easy-to-read approach to current trends in nanoscale colloid chemistry, which offers relatively simple and economically feasible ways to produce nanomaterials. Nanocolloids have been the subjects of major development in modern technology, with many current and future applications. The book helps scientists and technologists to understand the different aspects of modern nanocolloid science. It outlines the underlying fundamental principles of nanocolloid science and covers applications ranging from emulsions to dispersions and suspensions. You will find details on experimental techniques and methods for the synthesis and characterization of nanocolloids, including the latest developments in nanoemulsions and nanoparticles. - Edited by leading academics with over 10 years' experience in the field of colloid and surfactant science - Each chapter is authored by recognized experts in the field - Outlines the underlying fundamental science behind nanocolloids - Provides comprehensive coverage of current topics and potential applications in nanocolloid science - Presents a multidisciplinary approach to help chemical engineers, chemists, physicists, materials scientists and pharmacologists, form an in-depth understanding of nanocolloid science
This volume contains a comprehensive compilation of chromogenic and fluorescent RNA in situ hybridization (ISH) technology in many of its various shades, forms, and applications. The book is organized into a number of parts and chapters focusing on the application of ISH methodologies to different animal species as used in Evolutionary Development (EvoDevo) and Biomedical research, and covering new developments in RNA visualization by fluorescent ISH (FISH). The described (F)ISH protocols employ effective strategies for signal enhancement and target amplification allowing for high signal intensities and drastically improved signal-to-noise ratios. Chromogenic and fluorescent ISH, as specified in the various chapters, are most essential for RNA expression profiling, applied to many fields of research including cellular, developmental, and evolutionary biology, neurobiology and neuropathology. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Essential and authoritative, In Situ Hybridization Methods provides detailed protocols for newcomers to ISH, and inspires researchers familiar with the technique to seek and find up-to-date methodology for new and specialized applications.
The study of electrochemical reactions by relaxation or transient techniques has expanded rapidly over the last two decades. The impetus for the develop ment of these techniques has been the desire to obtain quantitative data on the rates of "fast" electrochemical processes, including those coupled to homogeneous chemical reactions in solution. This has necessarily meant the development of techniques that are capable of delineating the effects of mass transport and charge transfer at very short times. The purpose of this book is to describe how the various transient techniques may be used to obtain the desired information. Emphasis is placed upon the detailed mathematical development of the subject, since this aspect is the most frequently ignored in other texts in this field. In any relaxation or transient technique for the study of rate processes, it is necessary to disturb the reaction from equilibrium or the steady state by applying a perturbing impulse to the system. The system is then allowed to relax to a new equilibrium or steady-state position, and. the transient (i. e. , the response as a function of time) is analyzed to extract the desired kinetic information. In electrochemical studies the heterogeneous rate constants are, in general, dependent upon the potential difference across the interface, so that the perturbing impulse frequently takes the form of a known variation in potential as a function of time.
Photoplethysmography: Technology, Signal Analysis, and Applications is the first comprehensive volume on the theory, principles, and technology (sensors and electronics) of photoplethysmography (PPG). It provides a detailed description of the current state-of-the-art technologies/optical components enabling the extreme miniaturization of such sensors, as well as comprehensive coverage of PPG signal analysis techniques including machine learning and artificial intelligence. The book also outlines the huge range of PPG applications in healthcare, with a strong focus on the contribution of PPG in wearable sensors and PPG for cardiovascular assessment. - Presents the underlying principles and technology surrounding PPG - Includes applications for healthcare and wellbeing - Focuses on PPG in wearable sensors and devices - Presents advanced signal analysis techniques - Includes cutting-edge research, applications and future directions
