Spliced

Spliced

Author: Jon McGoran

Publisher: Holiday House

Published: 2017-09-29

Total Pages: 411

ISBN-13: 0823439291

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Sixteen-year-old Jimi knows people change, but nothing could prepare her for what’s about to happen to her best friend, Del. Over the years, their friendship has been evolving—and Jimi is starting to wonder if they could become more than friends. But Del is obsessed with becoming a chimera: a person with animal features, achieved by splicing animal genes into their own DNA. It's a dangerous and controversial process, provided illegally by back-alley doctors called genies. The dramatic physical changes chimeras go through have scared lawmakers into drafting legislation to declare chimeras officially non-human— taking away all protections under the law. When Del goes missing, Jimi is desperate to find him before he alters himself forever. To save him, Jimi must risk her life—all while knowing that if getting spliced is the choice Del has made, it means he’s leaving her behind forever. Unlikely allies and powerful enemies clash as Jimi questions her beliefs and uncovers closely-guarded secrets about her own past. Set in a near-future society where technology is redefining what it means to be human, Spliced is part science fiction, part political thriller, raising questions about genetic modification and how we treat each other that will stay with you long after the final page. The hardcover and paperback editions features a striking, texturally-embossed spot gloss cover, and the paperback features a sneak-peak at the heart-pounding sequel, Splintered. A Hal Clement Notable Young Adult Book 2018


Splicing Modern Ropes

Splicing Modern Ropes

Author: Jan-Willem Polman

Publisher: Bloomsbury Publishing

Published: 2016-05-05

Total Pages: 178

ISBN-13: 1472924916

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The time when every vessel going to sea made use of 3-strand rope has gone. Splicing that type of rope and cord is relatively straightforward. Nowadays the most common type of rope used on board yachts, dinghies, motorboats, working boats and ferries is braided rope. Few people have the knowledge to splice it, or even where to start. Splicing Modern Ropes is the first guide to this essential skill. It explains why splices are better – and stronger – than knots or shackles for joining or shortening rope, and how to go about it. With this skill, yachtsmen can customise their ropes, optimise their deck layout, taper their sheets for ease of handling, and splice an extra cover on their ropes to give better grip, avoid chafe and make them last longer. Using clear, step-by-step photography and detailed instructions, this book will guide readers through all the stages required to make strong, reliable splices.


Splice Magic

Splice Magic

Author: Tiffany Hayes

Publisher:

Published: 2021-12-15

Total Pages:

ISBN-13: 9780578333755

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Splice Magic is a groundbreaking quilting technique by Tiffany Hayes of Needle in a Hayes Stack. Tiffany Hayes, together with Kristie J. Smith and a host of friends, created a pattern book of 10 quilts to showcase the Splice Magic technique. The book is sponsored by Stitchin' Heaven, in Quitman, TX.


Regulation of Alternative Splicing

Regulation of Alternative Splicing

Author: Philippe Jeanteur

Publisher: Springer Science & Business Media

Published: 2013-03-14

Total Pages: 254

ISBN-13: 3662097281

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The discovery in 1977 that genes are split into exons and introns has done away with the one gene - one protein dogma. Indeed, the removal of introns from the primary RNA transcript is not necessarily straightforward since there may be optional pathways leading to different messenger RNAs and consequently to different proteins. Examples of such an alternative splicing mechanism cover all fields of biology. Moreover, there are plenty of occurrences where deviant splicing can have pathological effects. Despite the high number of specific cases of alternative splicing, it was not until recently that the generality and extent of this phenomenon was fully appreciated. A superficial reading of the preliminary sequence of the human genome published in 2001 led to the surprising, and even deceiving to many scientists, low number of genes (around 32,000) which contrasted with the much higher figure around 150,000 which was previously envisioned. Attempts to make a global assessment of the use of alternative splicing are recent and rely essentially on the comparison of genomic mRNA and EST sequences as reviewed by Thanaraj and Stamm in the first chapter of this volume. Most recent estimates suggest that 40-60% of human genes might be alternatively spliced, as opposed to about 22% for C. elegans.


RNA Splicing and Backsplicing: Disease and Therapy

RNA Splicing and Backsplicing: Disease and Therapy

Author: Rosanna Asselta

Publisher: Frontiers Media SA

Published: 2020-12-24

Total Pages: 197

ISBN-13: 2889662357

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.


Optical Fiber Fusion Splicing

Optical Fiber Fusion Splicing

Author: Andrew D. Yablon

Publisher: Springer

Published: 2005-12-17

Total Pages: 315

ISBN-13: 3540265392

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This book is an up-to-date treatment of optical fiber fusion splicing incorporating all the recent innovations in the field. It provides a toolbox of general strategies and specific techniques that the reader can apply when optimizing fusion splices between novel fibers. It specifically addresses considerations important for fusion splicing of contemporary specialty fibers including dispersion compensating fiber, erbium-doped gain fiber, polarization maintaining fiber, and microstructured fiber. Finally, it discusses the future of optical fiber fusion splicing including silica and non-silica based optical fibers as well as the trend toward increasing automation. Whilst serving as a self-contained reference work, abundant citations from the technical literature will enable readers to readily locate primary sources.


Notes, Splices and Rope Work

Notes, Splices and Rope Work

Author: A. HYATT VERRILL

Publisher: VICTORIA INSTITUTIONS

Published:

Total Pages: 32

ISBN-13:

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A PRACTICAL TREATISE Giving Complete and Simple Directions for Making All the Most Useful and Ornamental Knots in Common Use, with Chapters on Splicing, Pointing, Seizing, Serving, etc. Adapted for the Use of Travellers, Campers, Yachtsmen, Boy Scouts, and All Others Having to Use or Handle Ropes for Any Purpose.