The ROAD TO #50 continues here! Enjoy a TEN-ISSUE-long adventure leading up to the EPIC SHOWDOWN in milestone issue #50. Amy, Tangle, Jewel, and Belle’s peaceful camping trip is still up in flames… literally. The fire is blazing but all the tension from before has melted away and the heroines are ready to save the day! Plus, being confronted with such danger has some reevaluating their futures… Find out more in the final part of “Trial by Fire”!
The road to issue #50 continues here! Enjoy a TEN-ISSUE-LONG-ADVENTURE leading up to the EPIC SHOWDOWN in milestone issue #50. The Chaotix are on the case! Central City has been turned upside-down by unmanageable traffic, and reports of lightning and water moving in odd ways have the city’s emergency services scratching their heads. Is it a sewer-dwelling crocodile, a pair of unruly brothers, or something more sinister? Whatever it may be, Vector, Espio, and Charmy are sure to uncover the truth.
Celebrate Sonic the Hedgehog's way-past-cool 30th birthday! The classic character comes to life in all-new stories from high-octane creators, some in their Sonic debuts! Fan-favorite writer Ian Flynn returns to the blue blur, joined by Adventure Zone creators and New York Times bestselling authors Justin, Travis, and Griffin McElroy, as well as USA Today bestselling author Gale Galligan! Try to keep up with Sonic and his friends on adventures inspired by the original 2D games! Miles "Tails" Prower, Knuckles the Echidna, Amy Rose, Mighty the Armadillo, Ray the Flying Squirrel, and even more special guests travel with him through zones inspired by the seasons in search of Chaos Emeralds! It's a hilarious and hectic race against the clock in "Seasons of Chaos" by Ian Flynn! Plus stories by some of Sonic the Hedgehog's biggest fans and tons of bonus content celebrating the fastest thing alive! This special anniversary collection is the perfect piece of pop culture memorabilia for all Sonic fans!
The Super Sonic Warrior returns in “Genesis of a Hero” Part Three: The 25th anniversary celebration continues with another blast to the past! Which is also to the future, and the past, and back again! When Sonic goes to see the annual return of Little Planet, he’s surprised to find it chained to a mountain! Join us for the exciting adventures of Sonic CD! Featuring cover art by the legendary Patrick Spaziante.
"All For One," Part Two. The Chaotix are on the hunt for the missing Mighty and Ray, and their investigation takes them to the heart of enemy territory! With the Mercian Freedom Fighters at their side, will they find the vital clue they need? Or will Lord Hood claim more prisoners for his dungeon?
The penultimate chapter to the ultimate Mega Man epic is here! "The Ultimate Betrayal" Part Three: Mega Man must brave the many difficult challenges of Dr. Wily’s newest castle! Awaiting Mega Man in the trapped-filled halls of the ferocious fortress is the vicious and super-powerful Doc Robot! After seeing the pure destruction from this ferocious machine at Light Labs, does our hero even stand a chance? Or is the dreaded Doc Robot truly unstoppable?! The answers to these questions and more, plus cover art from the legendary Patrick "SPAZ" Spaziante!
The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis.Key Features:* Novel transcriptional mechanisms that control repetitive pattern formation* Wide scale genetic screens for mutations affecting somitogenesis* Molecular/genetic control of pattern and tissue formation during somitogenesis* Transplantation of mouse embryo somites* Classical embryological approaches and concepts* Evolutionary perspectives on somitogenesis
The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis. - Novel transcriptional mechanisms that control repetitive pattern formation - Wide-scale genetic screens for mutations affecting somitogenesis - Molecular/genetic control of pattern and tissue formation during somitogenesis - Transplantation of mouse embryo somites - Classical embryological approaches and concepts - Evolutionary perspectives on somitogenesis
It has been remarked that if the brain were so simple we could understand it, we would be so simple we couldn’t. However, as the authors of this accessible guide demonstrate, there are at least some things we do understand about the brain, and this knowedge can shed new light on our conception of ourselves and the workings of our minds. Covering crude ancient neuroscience, sleep, language and even philosophical questions about the nature of consciousness, this lively and entertaining introduction assumes no previous scientific knowledge and will fascinate readers of all backgrounds.
Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. - Provides an overview of tendon biology, disease, and tissue engineering approaches - Presents modern, alternative approaches to developing functional tissue solutions discussed - Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine - Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices - Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field
