This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Tanya Huff’s supernatural fantasy Smoke series, with a gothic twist • Mix of ghostly mystery, paranormal horror, and dark humor • Lamba Award nominated Fans of the X-Files and Twin Peaks will love acclaimed master of contemporary fantasy Tanya Huff’s twisted version of vampires, wizards, and TV terror. Tony Foster, fledgling wizard and now trainee assistant director on Darkest Night—the syndicated vampire detective show—is hoping that they only supernatural events he’ll be caught up in are those in the script. But that isn’t meant to be, for a demonic convergence is about to begin, creating weak spots through which lesser demons may enter the world. To complicate matters, Leah, the incredibly seductive stuntwoman who freelances for the show, is an immortal Demongate. Should Leah die, the Demongate will open and her sensual demon master will wreak havoc upon the unsuspecting human race. Can Tony—with the help of Leah, Henry, a tabloid reporter, a Mountie, and the cast of Darkest Night—halt a demonic invasion and stave off the end of the world?
Drinkina rye and water with Grandma. Guns in False Creek. Frat boy homies from the North Delta ghetto. Samuel L. Jackson. Phantom Lord & Metallica. A kid whoa s got the hots for his moma Hunh? Thata s right. Ita s all here in this collection of immediate, lean and visceral short fiction from Clint Burnham."
In this “incredible read on some incredible days and nights in the old association” (Adrian Wojnarowski, ESPN senior NBA insider) Charles Oakley—one of the toughest and most loyal players in NBA history—tells his unfiltered stories about his basketball journey and his relationships with Michael Jordan, LeBron James, Charles Barkley, Patrick Ewing, Phil Jackson, Pat Riley, James Dolan, Donald Trump, George Floyd, and many others. If you ask a New York Knicks fan about Charles Oakley, you better prepare to hear the love and a favorite story or two. But his individual stats weren’t remarkable, and while he helped power the Knicks to ten consecutive playoffs, he never won a championship. So why does he hold such a special place in the minds, hearts, and memories of NBA players and fans? Because over the course of nineteen years in the league, Oakley was at the center of more unbelievable encounters than Forrest Gump, and nearly as many fights as Mike Tyson. He was the friend you wish you had, and the enemy you wish you’d never made. If any opposing player was crazy enough to start a fight with him, or God forbid one of his teammates, Oakley would end it. “I can’t remember every rebound I grabbed but I do have a story—the true story—of just about every punch and slap on my resume,” he says. In The Last Enforcer, Oakley shares one incredible story after the next—all in his signature “unflinchingly tough, honest, and ultimately endearing” (Harvey Araton, New York Times bestselling author) style—about his life in the paint and beyond, fighting for rebounds and respect. You’ll look back on the era of the 1990s NBA, when tough guys with rugged attitudes, unflinching loyalty, and hard-nosed work ethics were just as important as three-point sharpshooters. You’ll feel like you were on the court, in the room, can’t believe what you just saw, and need to tell everyone you know about it.
"With potent, lyrical language and a profound knowledge of storytelling, Shaw encourages and illuminates the mythic in our own lives. He is a modern-day bard." – Madeline Miller, author of Circe and The Song of Achilles At a time when we are all confronted by not one, but many crossroads in our modern lives—identity, technology, trust, politics, and a global pandemic—celebrated mythologist and wilderness guide Martin Shaw delivers Smoke Hole: three metaphors to help us understand our world, one that is assailed by the seductive promises of social media and shadowed by a health crisis that has brought loneliness and isolation to an all-time high. Smoke Hole is a passionate call to arms and an invitation to use these stories to face the complexities of contemporary life, from fake news, parenthood, climate crises, addictive technology and more. Shaw urges us to reclaim our imagination and untangle ourselves from modern menace, letting these tales be our guide. More Praise: "I can still remember the first time I heard Martin Shaw tell a story. The tale that emerged was like a living thing, bounding around, throwing itself at us there listening. I had never heard anything like it before." – Paul Kingsnorth, Booker shortlisted author of The Wake "Martin Shaw’s work is so very beautiful. A new animal. His love of images is deep and contagious." – Coleman Barks, author of The Essential Rumi "Through feral tales and poetic exegesis, Martin Shaw makes you re-see the world, as a place of adventure, and of initiation, as perfect home, and as perfectly other. What a gift." – David Keenan, author of Xstabeth "Shaw has so much wisdom and knowledge about the old stories, it emanates from his pores." – John Densmore, The Doors
Data suggest that exposure to secondhand smoke can result in heart disease in nonsmoking adults. Recently, progress has been made in reducing involuntary exposure to secondhand smoke through legislation banning smoking in workplaces, restaurants, and other public places. The effect of legislation to ban smoking and its effects on the cardiovascular health of nonsmoking adults, however, remains a question. Secondhand Smoke Exposure and Cardiovascular Effects reviews available scientific literature to assess the relationship between secondhand smoke exposure and acute coronary events. The authors, experts in secondhand smoke exposure and toxicology, clinical cardiology, epidemiology, and statistics, find that there is about a 25 to 30 percent increase in the risk of coronary heart disease from exposure to secondhand smoke. Their findings agree with the 2006 Surgeon General's Report conclusion that there are increased risks of coronary heart disease morbidity and mortality among men and women exposed to secondhand smoke. However, the authors note that the evidence for determining the magnitude of the relationship between chronic secondhand smoke exposure and coronary heart disease is not very strong. Public health professionals will rely upon Secondhand Smoke Exposure and Cardiovascular Effects for its survey of critical epidemiological studies on the effects of smoking bans and evidence of links between secondhand smoke exposure and cardiovascular events, as well as its findings and recommendations.
Isaiah Quintabe—an unlicensed detective for all seasons—and his best friend and masterful sidekick, Juanell Dodson, are at a crossroads in this latest installment of the "aggressively entertaining" IQ series (New York Times). This time, their lives may never be the same. Isaiah Quintabe is no longer IQ, the genius of East Long Beach; instead, he’s a man on the road and on the run, hiding in a small Northern California town when his room is broken into by a desperate young man on the trail of the state’s most prolific serial killer. His old partner, Juanell Dodson, must go straight or lose his wife and child. His devil’s bargain? An internship at an LA advertising agency, where it turns out the rules of the street have simply been dressed in business casual, but where the aging company’s fortunes may well rest on their ability to attract a younger demographic. Dodson—”the hustler’s hustler”—just may be the right man for the job. Ide is the crime writer’s crime writer, and he’s filled his best novel yet with desperate souls, courageous outcasts, an ex-stripper who’ll do anything to protect her son, and wild half-brothers who may be the very incarnation of evil. With deft plotting, lacerating humor, and a keen eye for the ways in which characters rise or fall based on their ties to one another, Smoke is Joe Ide’s crowning achievement.
Now in paperback, the heartstopping finale to the New York Times bestseller Flame in the Mist-- from the bestselling author of The Wrath and the Dawn. After Okami is captured in the Jukai forest, Mariko has no choice--to rescue him, she must return to Inako and face the dangers that have been waiting for her in the Heian Castle. She tricks her brother, Kenshin, and betrothed, Raiden, into thinking she was being held by the Black Clan against her will, playing the part of the dutiful bride-to-be to infiltrate the emperor's ranks and uncover the truth behind the betrayal that almost left her dead. With the wedding plans already underway, Mariko pretends to be consumed with her upcoming nuptials, all the while using her royal standing to peel back the layers of lies and deception surrounding the imperial court. But each secret she unfurls gives way to the next, ensnaring Mariko and Okami in a political scheme that threatens their honor, their love and the very safety of the empire.
Unforgiveable betrayals, devious motives, and forbidden love collide in the first installment of internationally bestselling author Sally Green's epic new fantasy series, perfect for Game of Thrones fans. In a land tinged with magic and a bustling trade in an illicit supernatural substance, destiny will intertwine the fates of five players: A visionary princess determined to forge her own path. An idealistic solider whose heart is at odds with his duty. A streetwise hunter tracking the most dangerous prey. A charming thief with a powerful hidden identity. A loyal servant on a quest to avenge his kingdom. Their lives intersect with a stolen bottle of demon smoke. As war approaches, they must navigate a tangled web of political intrigue, shifting alliances, and forbidden love in order to uncover the dangerous truth about the strangely powerful smoke that interwines their fates.
One last thing, if you do fall in love with him, please go slowly. Be careful. Trust your gut and know not all things are easy. Damaged things can become beautiful if they're placed in the right hands. -Love, GranA small town where pickup trucks rule, the farmer's market is bigger than the grocery store, and just about everyone goes to church on Sunday is the last place Henley Warren expects to find herself three months after her grandmother's death. But Gran left a list of things she needed Henley to do after she died, and fulfilling those wishes means spending a summer in the same place her mom fled from when she was only seventeen years old. With each task that is ticked off the list, events are set in motion that uncover secrets surrounding Henley's life. Although Henley may have arrived on the shores of Alabama's Gulf Coast feeling alone and lost in a world without her Gran, things soon change. The small town holds more than she realized- including a broody, gorgeous, potentially dangerous guy who is always showing up when she needs him the most. Henley fears her heart isn't ready to trust someone so unpredictable but he makes her feel things deeper than she thought possible. So, when Henley discovers the twisted, dark world he is living in, will it be too late to save her heart? Or has her heart been beyond saving from the moment he stepped out of his truck on that very first day?
