This book is an indispensable reference for developers and administrators who want to maximize the performance of their Sun systems. Revised and updated to cover the latest SPARC and software release (including Solaris 2.6). This book presents a collaboration of configuration and performance information not available anywhere else.
Offering insight into the Solaris 2.x environment and its related migration strategy, this book contains an overview of the key technologies incorporated in Solaris 2.x, including SPARC and x86 platforms. KEY TOPICS: Covers emerging technologies, such as the Common Desktop Environment (CDE), provides hints for application performance tuning, and gives extensive pointers to further sources of information. MARKET: For software developers and programmers interested in Solaris.
This book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters. Pioneering topics covered include aptamer pharmaceuticals, aptamers for malign tumors, aptamers for personalized therapeutics and aptamers for point-of-care testing. The book offers an essential guide for medical scientists interested in developing aptamer-based schemes for better theranostics. It is therefore of interest for not only academic researchers, but also practitioners and medical researchers in various fields of medical science, medical research and bio-analytical chemistry.
OpenGL® is the world's leading cross-platform computer graphics software interface. Now, the world's most authoritative OpenGL® 1.2 tutorial and reference are available together for the first time, in an attractive, specially priced gift box. This is the definitive OpenGL® resource -- and an outstanding gift to every serious graphics programmer. The OpenGL® Programming Guide, Third Edition delivers definitive, comprehensive information on both OpenGL® and the OpenGL® Utility Library, covering all OpenGL® functions and showing how to use these functions to create powerful interactive applications and realistic color images. Coverage ranges from basic rendering, viewing, lighting, and texturing techniques to advanced texture mapping, antialiasing, effects, NURBS, image processing, optimization, cross-platform issues, and more. The OpenGL® Reference Manual, Third Edition is the definitive, official reference to all OpenGL® 1.2 functions, including new features such as 3D texture mapping; multitexturing; bitmapped texture level-of-detail control; new pixel storage formats; rescaling vertex normals; specular lighting after texturing; new OpenGL® Utility Library 1.3 routines; added X Window System functionality, and more.
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
This volume details protocols on formulation, surface modification, characterization, and application of a variety of pharmaceutical nanocarriers such as micelles, nanoparticles, dendrimers, carbon dots, polymersomes, and others. Chapters are targeted toward investigators working in academic and industrial laboratories conducting research in the broad field of pharmaceutical sciences, with an emphasis on drug delivery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pharmaceutical Nanotechnology: Basic Protocols aims to be a source of inspiration to all investigators who are interested in the potential of the merger of nanotechnology with pharmaceutical sciences.
Rodent Malaria reviews significant findings concerning malaria parasites of rodents, including their taxonomy, zoogeography, and evolution, along with life cycles and morphology; genetics and biochemistry; and concomitant infections. This volume is organized into eight chapters and begins by sketching out the history of the discovery of rodent as well as aspects of parasitology, immunology, and chemotherapy. These concepts are investigated two decades following Ignace Vincke's major discovery and Meir Yoeli's successful establishment of the method of cyclical transmission of the parasite. The following chapters focus on the taxonomy and systematics of the subgenus Vinckeia, with reference to the concepts of species and subspecies of animals and the degree to which they apply to malaria parasites, in particular to those of rodents. The discussion then shifts to how the rodent malaria parasites provide a unique insight into the subcellular organization of Plasmodium species, the use of rodent malaria as an experimental model to study immunological responses, and infectious agents that interact with malaria parasites. The book concludes with a chapter on malaria chemotherapy, with emphasis on the value of rodent malaria in antimalarial drug screening and the use of antimalarial drugs as biological probes. This book will be of interest to protozoologists and physicians as well as those from other disciplines including biochemistry, immunology, pharmacology, cell biology, and genetics.
Biopolymer-Based Formulations: Biomedical and Food Applications presents the latest advances in the synthesis and characterization of advanced biopolymeric formulations and their state-of-the-art applications across biomedicine and food science. Sections cover the fundamentals, applications, future trends, environmental, ethical and medical considerations, and biopolymeric architectures that are organized in nano, micro and macro scales. The final section of the book focuses on novel applications and recent developments. This book is an essential resource for researchers, scientists and advanced students in biopolymer science, polymer science, polymer chemistry, polymer composites, plastics engineering, biomaterials, materials science, biomedical engineering, and more. It will also be of interest to R&D professionals, scientists and engineers across the plastics, food, biomedical and pharmaceutical industries. - Provides in-depth coverage of methods for the characterization of the physical properties of biopolymeric architectures - Supports a range of novel applications, including scaffolds, implant coatings, drug delivery, and nutraceutical encapsulation systems - Includes the use of experimental data and mathematical modeling, thus enabling the reader to analyze and compare the properties of different polymeric gels
SGI's X Windows graphics expert explains how to construct real and useful 3D applications using OpenGL and X, and how to tightly integrate OpenGL applications with the X Window System. Using the OpenGL Utility Toolkit (GLUT) to show how OpenGL programs can be quickly constructed, the book explores OpenGL features using examples written in GLUT.