Small Heat Shock Proteins and Protection Against Cardiac Ischemic Damage
Author: Jody L. Martin
Publisher:
Published: 1997
Total Pages: 258
ISBN-13:
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Myocardial Ischemia and Preconditioning
Author: Naranjan S. Dhalla
Publisher: Springer Science & Business Media
Published: 2002-12-31
Total Pages: 564
ISBN-13: 9781402071959
DOWNLOAD EBOOKCurrent evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.
The Big Book on Small Heat Shock Proteins
Author: Robert M. Tanguay
Publisher: Springer
Published: 2015-06-15
Total Pages: 603
ISBN-13: 331916077X
DOWNLOAD EBOOKBased upon a workshop entitled “The Small HSP World” held in Québec 2-5 October 2014. Twenty-five scientists provided chapters for the book. The chapters are from the best scientists currently working in this field. These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu. Briefly, the book starts with the structure of small heat shock proteins, moving to their functions and finishing with their involvement in diseases. Although this is quite broad, the structural aspect will be the unifying theme of the book.
Myocardial Protection
Author: Tomas A. Salerno
Publisher: John Wiley & Sons
Published: 2008-04-15
Total Pages: 344
ISBN-13: 1405178434
DOWNLOAD EBOOKMyocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.
Heat Shock Proteins in Myocardial Protection
Author: Rakesh C. Kukreja
Publisher: CRC Press
Published: 2000-08-01
Total Pages: 145
ISBN-13: 1498712665
DOWNLOAD EBOOKMyocardial ischemic syndromes pose a major medical problem and a significant economic health care concern. Reperfusion, although used in the clinical arena as essential to the survival of acutely ischemic heart muscle carries with it the risk of reperfusion injury. Therefore the salvage of additional myocardium is highly desirable.
Myocardial Ischemia: Mechanisms, Reperfusion, Protection
Author: Morris Karmazyn
Publisher: Birkhäuser
Published: 2013-03-12
Total Pages: 508
ISBN-13: 3034889887
DOWNLOAD EBOOKMyocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.
Heat Shock Proteins and Cytoprotection
Author: Alexander E. Kabakov
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 244
ISBN-13: 1461560071
DOWNLOAD EBOOKHeat Shock Proteins and the Cardiovascular System
Author: A.A. Knowlton
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 341
ISBN-13: 1461561779
DOWNLOAD EBOOKHeat shock proteins (HSP) were originally described in heat-shocked drosophila by Ritossa in the early 1960's. In the last 5 years it has become apparent that these heat shock proteins have important functions both in the normal cell and in the stressed cell. These proteins constitute an endogenous protective system; mutations in the heat shock proteins can be lethal, and there are no known organisms without heat shock proteins. The first observations on heat shock proteins and the heart were made in the 1980's and interest in these proteins increased over the decade. In the last few years there has been an exponential growth in number of papers published on heat shock proteins and the heart. Heat shock proteins have been implicated in a number of cardiovascular research areas including ischemia, hypertrophy, aging, and atherosclerosis, and this list is growmg. The purpose of this volume is to give an overview of our current understanding of the heat shock proteins in the cardiovascular system, and to summarize the approaches to the study of heat shock proteins in the heart. This volume assembles results from a number of different cardiovascular fields. and provides a comprehensive review of heat shock proteins in the cardiovascular system.
Myocardial Protection
Author: Derek M. Yellon
Publisher:
Published: 1992
Total Pages: 232
ISBN-13:
DOWNLOAD EBOOKAn insight into the theories and controversies regarding myocardial reperfusion and reperfusion-induced injury. The ideas presented advance the understanding of the relationship of reperfusion injury to the beneficial effects of restoring coronary flow to the myocardium after an ischemic insult.
Small Stress Proteins
Author: A.-P. Arrigo
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 277
ISBN-13: 3642563481
DOWNLOAD EBOOKThis book gives a comprehensive survey of the current knowledge of the expression and function of small stress proteins (sHsps) in different organisms, from prokaryotes to humans. It provides an overview of the diversity and complex evolutionary history of sHsps and describes their function and expression in different eukaryote models. Additional chapters discuss the role of sHsps in pathological conditions and gene therapy approaches towards a control of sHsp expression levels.
