Dermatologists are often the first medical professionals to see patients with HIV infection, as skin diseases are common in acquired immunodeficiency syndrome. This book aims to help dermatologists recognize the cutaneous manifestations of HIV infection and AIDS, so that diagnosis can be made quickly and therapy begun as soon as possible. The book
HIV infection involves all systems of our body and diseases manifest in atypical and severe forms leading to lot of morbidity and mortality. Skin being the largest organ of the body and with mucous membranes, it is the main portal of HIV infection. There is a lot of scope for research in the field of HIV and AIDS, and there is a need for an updated literature that would throw a light on the efficient diagnosis and management of cutaneous manifestations in HIV disease. Hence we are bringing out this eBook which is a comprehensive literature on HIV and its various cutaneous manifestations in its entirety. In this eBook we have provided extensive data and information on various skin related infections, papulosquamous disorders, disorders of vasculature, pruritic papular eruptions, neoplasias, adverse drug reactions and other hair, nail, oral and ocular associated disorders in HIV. The work has been sufficiently researched and contributed by experts in this field. Clinical photographs and extensive scientific literature will enhance the knowledge and confidence of the readers particularly clinicians and postgraduates to efficiently diagnose and manage cutaneous diseases in HIV infected patients. We acknowledge the work and sincere efforts of all the contributors who have made this project to happen. Sincere thanks to Dr. Eswari L and Dr. Shwetha S for their support and help in bringing out this edition. Thanks to my spouse and daughters for their encouragement and support and especially to the publishers without whom this work would go unnoticed. We hope that this conscious effort will benefit the readers and in turn the people living with HIV- AIDS at large.
Nearly all patients infected with the human immunodeficiency virus (HIV) will develop cutaneous or mucous membrane manifestations. Oral cavity lesions associated with HIV disease include candidiasis, hairy leukoplakia and Kaposi's sarcoma. Skin infections such as herpes simplex, herpes zoster, molluscum contagiosum, Staphylococcus aureus folliculitis and warts are often more severe than usual and may be refractory to therapy. Seborrheic dermatitis is the most common cutaneous eruption. The appearance of Kaposi's sarcoma in a patient younger than 60 years of age or in any individual with laboratory evidence of HIV infection is diagnostic of acquired immunodeficiency syndrome. Serious drug reactions may occur, despite the depressed cellular immunity associated with HIV infection.
Cutaneous manifestations are common in patients with HIV infection and mainly due to the immunodeficiency. In the initial stage of HIV infection, we frequently observe a rash of macular lesions. During the asymptomatic phase, the patients may typically show the following skin diseases: seborrhoic dermatitis, acneiform folliculitis, persistent herpes simplex, and infections with the human papilloma virus. In ARC and AIDS patients, 3 groups of skin disorders are found: cutaneous infections, skin tumors, and other mixed skin diseases. Herpes simplex and herpes zoster may develop into ulcerating and necrotising forms especially in patients with advanced immunodeficiency. The most frequent skin tumors in AIDS patients are the disseminated Kaposi's sarcoma and non-Hodgkin's lymphoma. More than 50% of the AIDS patients treated with trimethoprim/sulfamethoxazole developed a severe drug eruption. African and Caribbean patients with AIDS frequently suffer from pruritic skin lesions, the pathogenesis of which is not known. Aside from these cutaneous manifestations, a variety of other skin disorders have been reported in patients with HIV infection, ARC, or AIDS; future research will furnish definite proof whether they are correlated with HIV infection.
Bringing together thousands of the best dermatologic clinical and pathological photographs and figures from researchers and scientists around the world, this volume focuses on the most prevalent dermatologic disorders as they relate to cutaneous infectious and neoplastic conditions and procedural dermatology. It includes atypical presentations of various disorders, giving insight into differential diagnoses, helping to familiarize the reader with some of the rarest dermatologic disorders. Atlas of Dermatology, Dermatopathology and Venereology Volume 3 is written for dermatologists, dermatopathologists, and residents and summarizes data regarding any dermatologic disorder and syndrome. Each entry includes an introduction, clinical and pathological manifestations, diagnosis, differential diagnosis, and treatment and prognosis. div>/div/div/div
This book introduces a number of HIV/AIDS cases with mucocutaneous lesions. HIV/AIDS can manifest a variety of skin lesions due to immunological disorder, opportunistic infections and tumors always occur primarily with skin lesions. The cases included in this book reflect the diseases spectrum and evolution of mucocutaneous lesions at different stages before and after AIDS antiretroviral therapy (ART) as well. This book consists of nine chapters, including fungal, viral, bacterial, parasitic, neoplastic, inflammatory diseases, syphilis and ART-induced diseases, etc. More than 300 cases and 600 photos of representative and important clinical significances are selected, showing the different clinical characteristics of the same disease under different immune status. Clinical photos are combined with clear and concise medical history along with the discussion on it, by which the readers can understand why skin lesions can be used as the early diagnostic clues to HIV/AIDS infection. Moreover, every chapter summarizes the similarity and characteristics of each type of skin diseases, which outlines and explains why they are AIDS-related mucocutaneous lesions.
This book introduces a number of HIV/AIDS cases with mucocutaneous lesions. HIV/AIDS can manifest a variety of skin lesions due to immunological disorder, opportunistic infections and tumors always occur primarily with skin lesions. The cases included in this book reflect the diseases spectrum and evolution of mucocutaneous lesions at different stages before and after AIDS antiretroviral therapy (ART) as well. This book consists of nine chapters, including fungal, viral, bacterial, parasitic, neoplastic, inflammatory diseases, syphilis and ART-induced diseases, etc. More than 300 cases and 600 photos of representative and important clinical significances are selected, showing the different clinical characteristics of the same disease under different immune status. Clinical photos are combined with clear and concise medical history along with the discussion on it, by which the readers can understand why skin lesions can be used as the early diagnostic clues to HIV/AIDS infection. Moreover, every chapter summarizes the similarity and characteristics of each type of skin diseases, which outlines and explains why they are AIDS-related mucocutaneous lesions.
The updated second edition of Cutaneous Manifestations of Infection in the Immunocompromised Host is an invaluable reference for physicians and ancillary medical professionals involved in the care of patients with impaired immune systems due to cancer, chemotherapy, systemic steroids and other immunosuppressive drugs, HIV/AIDS or organ transplantation. This volume will help you recognize skin lesions and diagnose their infectious cause. Textbook features include: · Over 350 color images demonstrating pathognomonic, atypical, rare and routine skin lesions · Tables for differential diagnosis of different skin lesions in the immunocompromised host · Complete coverage of infectious pathogens with the patterns of infection and the likely causes in different clinical settings (HIV/AIDS versus solid organ transplantation versus neutropenia post-chemotherapy versus bone marrow recovery post hematopoietic stem cell transplantation ) · New chapter discussing the role of viruses causing malignancies with cutaneous signs in the immunocompromised patient Written by dermatologists, the new edition is an indispensable diagnostic tool intended for use by all clinicians who care for immunocompromised patients.
