The chromosome complement (karyotype) often differs between related mammalian species (including humans vs chimpanzees), such that evolutionary biologists muse whether chromosomal difference is a cause or a consequence of speciation. The common shrew is an excellent model to investigate this problem because of its many geographical races (potential species) differing chromosomally, and its several sibling species (recently speciated forms) that are also chromosomally different. This system is an exceptional opportunity to investigate the role of chromosomes in speciation and this volume reflects detailed research following these approaches. Highlights include the demonstration that chromosomal re-arrangements can be associated with complete loss of gene flow and thus speciation and that selection within species hybrid zones may lead to de-speciation rather than speciation. This book represents an extraordinarily detailed consideration of the role of chromosomes in speciation in one astonishing species, providing insights to those interested in mammalian diversity, chromosomal evolution and speciation.
Stem cell science has the potential to impact human reproductive medicine significantly - cutting edge technologies allow the production and regeneration of viable gametes from human stem cells offering potential to preciously infertile patients. Written by leading experts in the field Stem Cells in Reproductive Medicine brings together chapters on the genetics and epigenetics of both the male and female gametes as well as advice on the production and regeneration of gene cells in men and women, trophoblasts and endometrium from human embryonic and adult stem cells. Although focussing mainly on the practical elements of the use of stem cells in reproductive medicine, the book also contains a section on new developments in stem cell research. The book is essential reading for reproductive medicine clinicians, gynecologists and embryologists who want to keep abreast of practical developments in this rapidly developing field.
A renowned biologist provides a sweeping chronicle of more than four billion years of life on Earth, shedding new light on evolutionary theory and history, sexual selection, speciation, extinction, and genetics.
The Causes and Consequences of Chromosomal Aberrations explores one of the most dramatic examples of genomic instability-chromosomal aberrations. It describes some of the more recent techniques used to map genes within the human genome, study chromosomal aberrations at the cellular level, and define the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The Causes and Consequences of Chromosomal Aberrations also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations, which offer separate instructive treatises on specific malignancies. The Causes and Consequences of Chromosomal Aberrations is useful to medical and graduate students, physicians, molecular biologists, and cytogeneticists. It will benefit anyone interested in the concepts, contributions, and development in the field of molecular cytogenetics.
There are nearly 6,000 mammalian species, among them our own. Research on our evolutionary cousins has a long history, but the last 20 years have seen particularly rapid progress in disentangling the interrelationships and evolutionary history of mammals. The present volume combines up-to-date reviews on mammalian phylogenetics with paleontological, taxonomic and evolutionary chapters and also summarizes the historical development of our insights in mammalian relationships, and thus our own place in the Tree of Life. Our book places the present biodiversity crisis in context, with one in four mammal species threatened by extinction, and reviews the distribution and conservation of mammalian diversity across the globe. This volume is the introductory tome to the new Mammalia series of the Handbook of Zoology and will be essential reading for mammalogists, zoologists and conservationists alike.
The second installment in a planned three-volume series, this book provides the first substantive review of South American rodents published in over fifty years. Increases in the reach of field research and the variety of field survey methods, the introduction of bioinformatics, and the explosion of molecular-based genetic methodologies have all contributed to the revision of many phylogenetic relationships and to a doubling of the recognized diversity of South American rodents. The largest and most diverse mammalian order on Earth—and an increasingly threatened one—Rodentia is also of great ecological importance, and Rodents is both a timely and exhaustive reference on these ubiquitous creatures. From spiny mice and guinea pigs to the oversized capybara, this book covers all native rodents of South America, the continental islands of Trinidad and Tobago, and the Caribbean Netherlands off the Venezuelan coast. It includes identification keys and descriptions of all genera and species; comments on distribution; maps of localities; discussions of subspecies; and summaries of natural, taxonomic, and nomenclatural history. Rodents also contains a detailed list of cited literature and a separate gazetteer based on confirmed identifications from museum vouchers and the published literature.
A valuable resource for the latest research on rodents, highlighting links across palaeontology, developmental biology, functional morphology, phylogenetics and biomechanics.
The first comprehensive treatment of North American rodents of conservation concern. This action plan summarizes the rodent fauna of North America and provides available information on every rodent taxon that has been considered to be of conservation concern by state, provincial and private conservation agencies and regional experts. It is hoped that the survey provided in this action plan will serve as a common ground for all these parties in drawing up conservation strategies for rodents.