Heat Shock Response

Heat Shock Response

Author: Lutz Nover

Publisher: CRC Press

Published: 2022-09-09

Total Pages: 532

ISBN-13: 1000714438

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This book focuses on heat shock response-an active yet transient reprogramming of cellular activities to the needs of a stress protection mechanism designed to minimize heat damage and to optimize restoration of normal cellular activities after the stress period. This work places major emphasis on the structure and possible cellular functions of heat shock proteins as well as the analysis of heat shock protein-coding genes by transfection into homologous and heterologous expression systems. It also discusses heat shock effects on all levels of gene expression, on cell ultrastructure, and metabolic activities. This unique text is a must for all those who are involved with genetics, nucleic acids research, and cancer research.


Caenorhabditis Elegans

Caenorhabditis Elegans

Author:

Publisher: Academic Press

Published: 2011-11-23

Total Pages: 513

ISBN-13: 0080925189

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An updated edition of the classic Methods in Cell Biology volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come. - Diverse, up-to-date techniques covered will be useful to the broadening community of C. elegans researchers for years to come - Chapters written by leaders in the field - Tried and true methods deliver busy researchers a one-stop compendium of essential protocols


Genetics, Development, and Evolution

Genetics, Development, and Evolution

Author: J. Perry Gustafson

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 363

ISBN-13: 1468451375

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One outstanding question in biology is the problem of devel opment: how the genetic instructions encoded in the DNA become expressed in the morphological, physiological, and behavioral features of multicellular organisms, through an ordered sequence of events that extend from the first cell division of the zygote to the adult stage and eventual death. The problem is how a one dimensional array of instructions is transformed into a four dimensional entity, the organism that exists in space and time. Understanding this transformation is, nevertheless, necessary for mastering the process of evolution. One hundred and twenty-five years after The Origin of Species, we have gained some understanding of evolution at the genetic level. Genetic information is stored in the linear sequence of nucleotides in the DNA. Gene mutations, chromosomal reorganiza tions, and a host of related processes introduce variation in the sequence and the amount of DNA. The fate of these variations is determined by interactions within the genome and with the outside environment that are largely understood. We have recently gained a glimpse of how the genome of eukaryotes is organized and will learn much more about it in the future, now that we have the research tools for it.


Ribosomes Structure, Function, and Dynamics

Ribosomes Structure, Function, and Dynamics

Author: Marina V. Rodnina

Publisher: Springer Science & Business Media

Published: 2011-12-10

Total Pages: 428

ISBN-13: 3709102154

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The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come.


Insect Timing

Insect Timing

Author: D.L. Denlinger

Publisher: Elsevier

Published: 2001-06-19

Total Pages: 245

ISBN-13: 0080534724

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Leading experts in the field bring together diverse aspects of insect timing mechanisms. This work combines three topics that are central to the understanding of biological timing in insects: circadian rhythms, photoperiodism, and diapause. The common theme underlining each of the contributions to this book is an understanding of the timing of events in the insect life cycle. Most daily activities (emergence, feeding, mating, egg laying, etc.) undertaken by insects occur at precise times each day. Likewise, seasonal events such as the entry into or termination from an overwintering dormancy (diapause) occur at distinct times of the year. This book documents such events and provides an up-to-date interpretation of the molecular and physiological events undergirding these activities.The study of circadian rhythms has undergone a flowering in recent years with the molecular dissection of the components of the circadian clock. Now that many of the clock genes have been identified it is possible to track daily patterns of clock-related mRNAs and proteins to link the entraining light cycles with molecular oscillations within the cell. Insect experiments have led the way in demonstrating that the concept of a "master clock" can no longer be used to explain the temporal organization within an animal. Insects have a multitude of cellular clocks that can function independently and retain their function under organ culture conditions, and they thus offer a premier system for studying how the hierarchical organization of clocks results in the overall temporal organization of the animal. Photoperiodism, and its most obvious manifestation, diapause, does not yet have the molecular underpinning that has been established for circadian rhythms, but recent studies are beginning to identify genes that appear to be involved in the regulation of diapause. Overall, the book presents the rich diversity of challenges and opportunities provided by insects for the study of timing mechanisms.


Cold-Adapted Organisms

Cold-Adapted Organisms

Author: Rosa Margesin

Publisher: Springer Science & Business Media

Published: 1999-05-06

Total Pages: 432

ISBN-13: 9783540649731

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Major parts of the oceans and lands of our planet are permanently, or temporarily, exposed to temperatures below 10 C. Microorganisms, plants and animals living under these conditions have adapted to their environments in such a way that metabolic processes, reproduction and survival strategies are optimal for their natural biotopes. This book presents the most recent knowledge of the ecology and the physiology of cold-adapted microorganisms, plants and animals, and explains the mechanisms of cold-adaptation on the enzymatic and molecular level, including results from the first crystal structures of enzymes of cold-adapted organisms.


The Holistic Guide to Hypnotherapy

The Holistic Guide to Hypnotherapy

Author: Steve Webster

Publisher: Balboa Press

Published: 2017-03-29

Total Pages: 426

ISBN-13: 1504376137

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The Holistic Guide to Hypnotherapy Here is the worlds most comprehensive and detailed revelation of the ancient art of hypnotherapy in two volumes. Whether you are currently learning it, practicing it, a hypnotherapy professional, or just plain interested in the amazing art of hypnotherapy, this book will be your most valuable resource. Hypnotherapy is not the only discipline covered in this huge store of knowledge: among many other things, you will learn about health from a holistic point of view, benefits of nutrition, meditation, about relationships, sexuality and more. Steve Webster brilliantly explains: ? Simple, complex and metaphysical hypnotherapy. ? The differences between hypnosis and hypnotherapy. ? Approaches and amazing new techniques to use on different personality types. ? How to use 18 Laws of Suggestibility to rid clients of illness, disease and behavioral disorder, and how to reprogram your mind. ? Mechanics of hypnosis, the scientific intricacies, and 27 diagnostic tools to help you.... ? How to treat the top 35 afflictions like weight loss, anxiety, pain, sleep disorders, and social phobias. ? Guided imagery, neuroplasticity, epigenetics, neuro-linguistic programming, ideomotor responses and the power of dream venting. ? Your clients coping, blocking, release, and defense mechanisms. ? Body syndromes, how emotions affect us, and the subconscious mind. ? How one health disorder, HHS, might be responsible for 85% of afflictions. ? The real Law of Attraction, and how to make it work for you. Steve has coined a new description for hypnotherapistsConsciousness Engineersbecause thats what they are! The clients consciousness creates their reality, and the hypnotherapist adjusts that consciousness. The subconscious mind vibrates at a level where it does not know illness, disease and behavioral disorder; but the conscious mind vibrates at a lower level and attracts these negative energies. After reading the Consciousness Engineering section (Volume 2), you will understand: ? Your 3 minds, their vibrational levels, and how to increase your power of creation. ? How to manifest anything, and how to become an ascended master. ? Learn what the subconscious mind is, and how to guide your client to engage with it, and harness its amazing powers. The two volumes explain how you create your whole world, and how to create a world that brings you (and your clients!) joy and peace. It explains levels of consciousness, how to increase yours, and how you are immortal in your quantum world. With over 100 inductions, deepeners and convincers, with over 100 original diagrams and images, and with over 100 informative tables and quotes. This book really is your hypnotherapy Bible!