Automated Machine Learning

Automated Machine Learning

Author: Frank Hutter

Publisher: Springer

Published: 2019-05-17

Total Pages: 223

ISBN-13: 3030053180

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This open access book presents the first comprehensive overview of general methods in Automated Machine Learning (AutoML), collects descriptions of existing systems based on these methods, and discusses the first series of international challenges of AutoML systems. The recent success of commercial ML applications and the rapid growth of the field has created a high demand for off-the-shelf ML methods that can be used easily and without expert knowledge. However, many of the recent machine learning successes crucially rely on human experts, who manually select appropriate ML architectures (deep learning architectures or more traditional ML workflows) and their hyperparameters. To overcome this problem, the field of AutoML targets a progressive automation of machine learning, based on principles from optimization and machine learning itself. This book serves as a point of entry into this quickly-developing field for researchers and advanced students alike, as well as providing a reference for practitioners aiming to use AutoML in their work.


Mechanisms of Catalysis

Mechanisms of Catalysis

Author:

Publisher: Academic Press

Published: 1991-01-28

Total Pages: 471

ISBN-13: 0080865968

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The remarkable expansion of information leading to a deeper understanding of enzymes on the molecular level necessitated the development of this volume which not only introduces new topics to The Enzymes series but presents new information on some covered in Volume I and II of this edition.


Service Science

Service Science

Author: Mark S. Daskin

Publisher: John Wiley & Sons

Published: 2011-07-15

Total Pages: 628

ISBN-13: 0470877863

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A comprehensive treatment on the use of quantitative modeling for decision making and best practices in the service industries Making up a significant part of the world economy, the service sector is a rapidly evolving field that is relied on to dictate the public's satisfaction and success in various areas of everyday life, from banking and communications to education and healthcare. Service Science provides managers and students of the service industries with the quantitative skills necessary to model key decisions and performance metrics associated with services, including the management of resources, distribution of goods and services to customers, and the analysis and design of queueing systems. The book begins with a brief introduction to the service sector followed by an introduction to optimization and queueing modeling, providing the methodological background needed to analyze service systems. Subsequent chapters present specific topics within service operations management, including: Location modeling and districting Resource allocation problems Short- and long-term workforce management Priority services, call center design, and customer scheduling Inventory modeling Vehicle routing The author's own specialized software packages for location modeling, network optimization, and time-dependent queueing are utilized throughout the book, showing readers how to solve a variety of problems associated with service industries. These programs are freely available on the book's related web site along with detailed appendices and online spreadsheets that accompany the book's "How to Do It in Excel" sections, allowing readers to work hands-on with the presented techniques. Extensively class-tested to ensure a comprehensive presentation, Service Science is an excellent book for industrial engineering and management courses on service operations at the upper-undergraduate and graduate levels. The book also serves as a reference for researchers in the fields of business, management science, operations research, engineering, and economics. This book was named the 2010 Joint Publishers Book of the Year by the Institute of Industrial Engineers.


Biomarkers of Human Aging

Biomarkers of Human Aging

Author: Alexey Moskalev

Publisher:

Published: 2019

Total Pages: 421

ISBN-13: 9783030249724

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This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function). The book goes on to describe DNA methylation, known as the "epigenetic clock," as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging. Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.


Early Diagnosis of Alzheimer's Disease

Early Diagnosis of Alzheimer's Disease

Author: Leonard F. M. Scinto

Publisher: Springer Science & Business Media

Published: 2000-02-09

Total Pages: 384

ISBN-13:

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The three major approaches to diagnosis of AD -- radiological, biological, and neurophysiological -- are discussed in detail with chapters highlighting the most promising technologies within these approaches. The leading authors, all of whom are intimately involved with these emerging technologies, have developed this as an essential reference for neuropathologists, clinicians and researchers of Alzheimer's disease.


International Poisonous Plants Checklist

International Poisonous Plants Checklist

Author: D. Jesse Wagstaff

Publisher: CRC Press

Published: 2008-07-07

Total Pages: 462

ISBN-13: 1420062530

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Knowledge of plant toxicity has always been important, but the information has not always been reliable. Now, increasing international trade is drawing attention to the inadequacy of regional information and highlighting the geographical fragmentation and notorious discrepancies of thinly documented information. The international community of safet


Engineering the Genetic Code

Engineering the Genetic Code

Author: Nediljko Budisa

Publisher: John Wiley & Sons

Published: 2006-05-12

Total Pages: 312

ISBN-13: 3527607099

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The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application. Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique. Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given. Essential reading for all molecular life scientists who want to stay ahead in their research.


Wines & Vines Of California: Or, A Treatise On The Ethics Of Wine Drinking

Wines & Vines Of California: Or, A Treatise On The Ethics Of Wine Drinking

Author: Frona Eunice Wait Smith Colburn

Publisher: Legare Street Press

Published: 2022-10-27

Total Pages: 0

ISBN-13: 9781015987432

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.


Epigenetics and Chromatin

Epigenetics and Chromatin

Author: Philippe Jeanteur

Publisher: Springer Science & Business Media

Published: 2008-09-10

Total Pages: 284

ISBN-13: 9783540852360

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Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence. This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.