Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects

Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects

Author: Sangita Das

Publisher: Elsevier

Published: 2022-09-16

Total Pages: 766

ISBN-13: 0323906729

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Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects provides a general overview of the development and performance of different novel molecular frameworks as potent vehicles for sensing Chemical Weapons (CWs). The chapters are contributed by leading researchers in the areas of materials science, medical science, chemical science, and nanotechnology from industries, academics, government and private research institutions across the globe. It covers cover topics such as inorganic nanocomposites, hyperbranched polymers, and graphene heterojunctions for effective sensing of CW agents. This book is a highly valuable reference source for graduates, post-graduates, and research scholars primarily in the fields of materials science, medicinal chemistry, organic chemistry, and nanoscience and nanotechnology. In addition, almost all analytical techniques will be discussed, making this a first-rate reference for professors, students, and scientists in many industries. Provides an efficient, reliable, and highly versatile approach for the synthesis of different molecular systems suitable for diversity-oriented strategies, structure-activity studies and molecular tailoring for the sensing of chemical warfare agents Goes into depth on new binary organogels, discrete carbon nanomaterials (CNMs) and molecularly imprinted polymers (MIPs) and has endowed electrochemical chemosensors (ECCSs) with high selectivity and sensitivity towards the detection of chemical warfare agent Highlights in detail the detection of CWs by composite optical waveguide sensors, and describes disposable biofilm biosensors for sensitive detection of biotoxicity in water with treatment of nerve agent poisoning


Chemical Warfare Agents

Chemical Warfare Agents

Author: Timothy T. Marrs

Publisher: John Wiley & Sons

Published: 2007-05-07

Total Pages: 751

ISBN-13: 0470013591

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Chemical Warfare Agents, Second Edition has been totally revised since the successful first edition and expanded to about three times the length, with many new chapters and much more in-depth consideration of all the topics. The chapters have been written by distinguished international experts in various aspects of chemical warfare agents and edited by an experienced team to produce a clear review of the field. The book now contains a wealth of material on the mechanisms of action of the major chemical warfare agents, including the nerve agent cyclosarin, formally considered to be of secondary importance, as well as ricin and abrin. Chemical Warfare Agents, Second Edition discusses the physico-chemical properties of chemical warfare agents, their dispersion and fate in the environment, their toxicology and management of their effects on humans, decontamination and protective equipment. New chapters cover the experience gained after the use of sarin to attack travellers on the Tokyo subway and how to deal with the outcome of the deployment of riot control agents such as CS gas. This book provides a comprehensive review of chemical warfare agents, assessing all available evidence regarding the medical, technical and legal aspects of their use. It is an invaluable reference work for physicians, public health planners, regulators and any other professionals involved in this field. Review of the First Edition: "What more appropriate time for a title of this scope than in the post 9/11 era? ...a timely, scholarly, and well-written volume which offers much information of immense current and…future benefit." —VETERINARY AND HUMAN TOXICOLOGY


Handbook of Toxicology of Chemical Warfare Agents

Handbook of Toxicology of Chemical Warfare Agents

Author: Ramesh C Gupta

Publisher: Academic Press

Published: 2009-04-02

Total Pages: 1182

ISBN-13: 0080922732

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This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with


Chemical Warfare Agents: Toxicology and Treatment

Chemical Warfare Agents: Toxicology and Treatment

Author: Dr Timothy T. Marrs

Publisher: Wiley

Published: 2007-04-04

Total Pages: 750

ISBN-13: 0470060026

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Chemical Warfare Agents, Second Edition has been totally revised since the successful first edition and expanded to about three times the length, with many new chapters and much more in-depth consideration of all the topics. The chapters have been written by distinguished international experts in various aspects of chemical warfare agents and edited by an experienced team to produce a clear review of the field. The book now contains a wealth of material on the mechanisms of action of the major chemical warfare agents, including the nerve agent cyclosarin, formally considered to be of secondary importance, as well as ricin and abrin. Chemical Warfare Agents, Second Edition discusses the physico-chemical properties of chemical warfare agents, their dispersion and fate in the environment, their toxicology and management of their effects on humans, decontamination and protective equipment. New chapters cover the experience gained after the use of sarin to attack travellers on the Tokyo subway and how to deal with the outcome of the deployment of riot control agents such as CS gas. This book provides a comprehensive review of chemical warfare agents, assessing all available evidence regarding the medical, technical and legal aspects of their use. It is an invaluable reference work for physicians, public health planners, regulators and any other professionals involved in this field. Review of the First Edition: "What more appropriate time for a title of this scope than in the post 9/11 era? ...a timely, scholarly, and well-written volume which offers much information of immense current and…future benefit." —VETERINARY AND HUMAN TOXICOLOGY


Chemical Warfare Agents

Chemical Warfare Agents

Author: Brian J. Lukey

Publisher: CRC Press

Published: 2019-04-11

Total Pages: 1197

ISBN-13: 0429631472

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The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11, 2001. The second edition titled, Chemical Warfare Agents: Pharmacology, Toxicology, and Therapeutics, included new epidemiological and clinical studies of exposed or potentially exposed populations; new treatment concepts and products; improved organization of the national response apparatus addressing the potential for CWA terrorism; and improved diagnostic tests that enable rapid diagnosis and treatment. Since the second edition, the chemical warfare agent community has worked hard to advance research for protection and treatment and develop/improve response approaches for individuals and definitive care. Consequently, in addition to updating previous chapters, Chemical Warfare Agents: Biomedical and Psychological Effects, Medical Countermeasures, and Emergency Response, Third Edition features several new chapters that address the Syrian War, chemical destruction, the Organisation for the Prohibition of Chemical Weapons, biomarkers for chemical warfare agent exposure, field sensors, aircraft decontamination, lung/human on a chip, chemical warfare response decision making, and other research advancements. Features: Describes the newest medical interventions, and the latest technologies deployed in the field, as well as developments in the international response to CW usage highlighting recent events in the Middle East Discusses the latest in organizational/interagency partitioning in terms of responsibilities for emergency response, not just in the United States but at the international level—whether prevention, mitigation, medical care, reclamation, or medico-legal aspects of such response Contains the most current research from bench-level experts The third edition contains the most up-to-date and comprehensive coverage of the question of chemical warfare agent employment on the battlefield or in terrorism. Edited by workers that have been in the field for 35+ years, it remains faithful to the scientific "constants," while evaluating and crediting the advances by the industry that have made us safer.


Analysis of Chemical Warfare Degradation Products

Analysis of Chemical Warfare Degradation Products

Author: Karolin K. Kroening

Publisher: John Wiley & Sons

Published: 2016-04-22

Total Pages: 168

ISBN-13: 1119970199

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This book describes nerve agents and vesicants, their decomposition and their degradation products' chemistry as well as their toxicity including a list of detection techniques of nerve agents and their degradation products. This book will present their history, toxicity, comparison between different sample preparation methods, separation techniques, and detection methods all together in a short, easy to read book, tied together by a single group doing the writing and the editing to assure smooth transition from chapter to chapter, with sufficient Tables and literature references for the reader who looks to further detail.The text will illustrate the pluses and minuses of the various techniques with sufficient references for the reader to obtain extensive detail.


Chemical Warfare Agents

Chemical Warfare Agents

Author: Timothy C. Marrs

Publisher: Wiley-Blackwell

Published: 1996-04-18

Total Pages: 264

ISBN-13:

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This book is an accessible and authoritative guide to the practical medical management of victims of chemical warfare and offers an explanation of the underlying pharmacology and toxicology of the various agents. It discusses all major classical chemical warfare agents including nerve agents, vesicants, lung damaging agents, respiratory poisons, irritants and psychoactive agents covering the toxicology, pharmacology, human studies and treatment options for each class. Also features a section on field management of chemical agent exposure.


Chemical Warfare Agents

Chemical Warfare Agents

Author: M. Somani Satu

Publisher: CRC Press

Published: 2000-12-07

Total Pages: 456

ISBN-13: 1420041576

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Many books cover the emergency response to chemical terrorism. But what happens after the initial crisis? Chlorine, phosgene, and mustard were used in World War I. Only years after the war were the long-term effects of these gases realized. In the 60s, 70s, and 80s, these and other agents were used in localized wars. Chemical Warfare Agents: Tox


Review of Acute Human-Toxicity Estimates for Selected Chemical-Warfare Agents

Review of Acute Human-Toxicity Estimates for Selected Chemical-Warfare Agents

Author: Committee on Toxicology

Publisher: National Academies Press

Published: 1997-08-14

Total Pages: 98

ISBN-13: 0309569192

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No reliable acute-exposure1 standards have been established for the particular purpose of protecting soldiers from toxic exposures to chemical warfare (CW) agents. Some human-toxicity estimates are available for the most common CW agents--organophosphorus nerve agents and vesicants; however, most of those estimates were developed for offensive purposes (that is, to kill or incapacitate the enemy) and were intended to be interim values only. Because of the possibility of a chemical attack by a foreign power, the Army's Office of the Surgeon General asked the Army's Chemical Defense Equipment Process Action Team (CDEPAT) to review the toxicity data for the nerve agents GA (tabun), GB(sarin), GD (soman), GF, and VX, and the vesicant agent sulfur mustard (HD) and to establish a set of exposure limits that would be useful in protecting soldiers from toxic exposures to those agents. This report is an independent review of the CDEPAT report to determine the scientific validity of the proposed estimates.


Detection Technologies for Chemical Warfare Agents and Toxic Vapors

Detection Technologies for Chemical Warfare Agents and Toxic Vapors

Author: Yin Sun

Publisher: CRC Press

Published: 2004-08-12

Total Pages: 288

ISBN-13: 9781566706681

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While it is not possible to predict — or necessarily prevent — terrorist incidents in which chemical warfare agents (CWAs) and toxic industrial chemicals (TICs) are deployed, correctly chosen, fast, and reliable detection equipment will allow prepared rescue workers to respond quickly and minimize potential casualties. Detection Technologies for Chemical Warfare Agents and Toxic Vapors discusses the principles, instrumentation, and context for applying technologies such as ion mobility spectrometry, infrared spectroscopy, colorimetric chemistry, and flame ionization to the detection of TICs and lethal CWAs. It conveys techniques — some of which have been patented by the authors — developed for generating vapors and closely imitating potential environmental effects in a laboratory setting, specifically for the testing and evaluation of hand-held, portable, and remote devices. This book also provides a comprehensive list of toxic industrial chemicals classified in terms of hazardousness and their physical, chemical, and toxicological properties. Following a brief historical overview, the text also includes a review of federal detection requirements and the government’s rationale for preparedness and response. By providing insight on the behavior of toxic chemicals, the authors hope to minimize the fear and chaotic effect in a potential event involving chemical agents. Well written and accessible to technical and non-technical audiences, no other book focuses on analytical methods and explains current detection devices for chemical warfare agents.