Proteins at Solid-Liquid Interfaces

Proteins at Solid-Liquid Interfaces

Author: Philippe Déjardin

Publisher: Springer Science & Business Media

Published: 2006-09-28

Total Pages: 341

ISBN-13: 3540326588

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This book opens with a description of fundamental aspects of protein adsorption to surfaces, a phenomenon that plays a key role in biotechnological applications, especially at solid-liquid interfaces. Presented here are methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy (OWLS). Also described are sensitive bench techniques for measuring the orientation and structure of proteins at solid-liquid interfaces, including total internal reflection ellipsometry (TIRE), dual polarisation interferometry (DPI) and time of flight - secondary ion mass spectrometry (TOF–SIMS). A model study of fibronectin at polymer surfaces is included, as are studies using microporous membranes and textiles with immobilized enzymes for large-scale applications. Biocompatibility, anti-fouling properties and surface modification to modulate the adsorption and activity of biomolecules are among the other topics addressed in this invaluable book.


Research and Applications in Global Supercomputing

Research and Applications in Global Supercomputing

Author: Segall, Richard S.

Publisher: IGI Global

Published: 2015-01-31

Total Pages: 696

ISBN-13: 1466674628

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Rapidly generating and processing large amounts of data, supercomputers are currently at the leading edge of computing technologies. Supercomputers are employed in many different fields, establishing them as an integral part of the computational sciences. Research and Applications in Global Supercomputing investigates current and emerging research in the field, as well as the application of this technology to a variety of areas. Highlighting a broad range of concepts, this publication is a comprehensive reference source for professionals, researchers, students, and practitioners interested in the various topics pertaining to supercomputing and how this technology can be applied to solve problems in a multitude of disciplines.


Adsorption and the Gibbs Surface Excess

Adsorption and the Gibbs Surface Excess

Author: D. Chattoraj

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 478

ISBN-13: 1461583330

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The subject matter of this book is not entirely new in that much has been written about the state of the interfacial chemistry in other textbooks. However, the authors have found that there is really a need for a book which can lead an investigator, a student, or a beginn er through the in-depth understanding and descriptions involved in the derivations and usage of the adsorption equations based on the unified concept of the Gibbs surface excess. The derivation of the original Gibbs equation for the liquid interface has been amplified with reformulations and criticisms. Attempts have been frequently made to relate the surface excess quantities with the thermodynamic properties of the physically defined interfacial phase. In the last two decades, useful applications of the Gibbs equations have been made for the study of adsorption at solid-liquid as weIl as liquid-gas interfaces formed in the presence of the multicomponent solutions in the bulk. These recent treatments become useful for the experimental studies of the adsorption of electrolytes and interfacial properties related to neutral and charged monolayers. The consistency of the experimental results with those to be expected from the theories of the electrical double layer needs careful examination. An attempt has been made to present in a single volume all these developments based on the unified concept of the Gibbs surface excess. The study of the adsorption from solution is of considerable importance in the field of biology and in many other branches of applied science.


Amino Acids, Peptides and Proteins

Amino Acids, Peptides and Proteins

Author: Maxim Ryadnov

Publisher: Royal Society of Chemistry

Published: 2016-11-17

Total Pages: 291

ISBN-13: 1782626611

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Amino Acids, Peptides and Proteins comprises a comprehensive and critical review of significant developments at the biology and chemistry interface. Compiled by leading researchers in their subject, this volume incorporates current trends and emerging areas for example discovery and validation of novel protein/peptide biomarkers, proteins and peptides for the diagnosis and therapy of a parasite infection and surface and interface analysis of functional proteins and peptides. Appealing broadly to researchers in academia and industry, it will be of great benefit to any researcher wanting a succinct reference to developments now and looking to the future.


Biophysical Methods for Biotherapeutics

Biophysical Methods for Biotherapeutics

Author: Tapan K. Das

Publisher: John Wiley & Sons

Published: 2014-02-27

Total Pages: 380

ISBN-13: 1118354680

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With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development. • Helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods • Chapters organized according to the sequential nature of the drug development process • Helps formulation, analytical, and bioanalytical scientists in pharma and biotech better understand and usestrengths and limitations of biophysical methods • Explains how to use biophysical methods, the information obtained, and what needs to be presented in a regulatory filing, assess impact on quality and immunogenicity • With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development.


Theory of Molecular Fluids

Theory of Molecular Fluids

Author: C. G. Gray

Publisher: International Monographs on Ch

Published: 1984

Total Pages: 785

ISBN-13: 0198556217

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Existing texts on liquid theory are limited to simple liquids of spherical molecules, but nearly all liquids of practical interest have molecules that are non-spherical, resulting in more diverse phenomena. This text is the first to provide the molecular theory for such liquids, and describes applications to a wide range of physical properties.


Handbook of Infrared Spectroscopy of Ultrathin Films

Handbook of Infrared Spectroscopy of Ultrathin Films

Author: Valeri P. Tolstoy

Publisher: John Wiley & Sons

Published: 2003-07-21

Total Pages: 710

ISBN-13: 0471461830

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Because of the rapid increase in commercially available Fouriertransform infrared spectrometers and computers over the past tenyears, it has now become feasible to use IR spectrometry tocharacterize very thin films at extended interfaces. At the sametime, interest in thin films has grown tremendously because ofapplications in microelectronics, sensors, catalysis, andnanotechnology. The Handbook of Infrared Spectroscopy of UltrathinFilms provides a practical guide to experimental methods,up-to-date theory, and considerable reference data, critical forscientists who want to measure and interpret IR spectra ofultrathin films. This authoritative volume also: Offers informationneeded to effectively apply IR spectroscopy to the analysis andevaluation of thin and ultrathin films on flat and rough surfacesand on powders at solid-gaseous, solid-liquid, liquid-gaseous,liquid-liquid, and solid-solid interfaces. Provides full discussion of theory underlying techniques Describes experimental methods in detail, including optimumconditions for recording spectra and the interpretation ofspectra Gives detailed information on equipment, accessories, andtechniques Provides IR spectroscopic data tables as appendixes, includingthe first compilation of published data on longitudinal frequenciesof different substances Covers new approaches, such as Surface Enhanced IR spectroscopy(SEIR), time-resolved FTIR spectroscopy, high-resolutionmicrospectroscopy and using synchotron radiation