Protein Structure
Protein Structure

Author: Daniel Chasman

Publisher: CRC Press

Published: 2003-03-18

Total Pages: 534

ISBN-13: 0824748166

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This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational methods to study protein structures and residues. A valuable reference, this book reflects current trends in the effort to solve new structures arising from genome initiatives, details methods to detect and identify errors in the prediction of protein structural models, and outlines challenges in the conversion of routine processes into high-throughput platforms.

Proceedings of the Second International Conference on Soft Computing for Problem Solving (SocProS 2012), December 28-30, 2012
Proceedings of the Second International Conference on Soft Computing for Problem Solving (SocProS 2012), December 28-30, 2012

Author: B. V. Babu

Publisher: Springer

Published: 2014-07-08

Total Pages: 1529

ISBN-13: 8132216024

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The present book is based on the research papers presented in the International Conference on Soft Computing for Problem Solving (SocProS 2012), held at JK Lakshmipat University, Jaipur, India. This book provides the latest developments in the area of soft computing and covers a variety of topics, including mathematical modeling, image processing, optimization, swarm intelligence, evolutionary algorithms, fuzzy logic, neural networks, forecasting, data mining, etc. The objective of the book is to familiarize the reader with the latest scientific developments that are taking place in various fields and the latest sophisticated problem solving tools that are being developed to deal with the complex and intricate problems that are otherwise difficult to solve by the usual and traditional methods. The book is directed to the researchers and scientists engaged in various fields of Science and Technology.

Structure-based Drug Discovery
Structure-based Drug Discovery

Author: Harren Jhoti

Publisher: Springer Science & Business Media

Published: 2007-05-24

Total Pages: 255

ISBN-13: 1402044070

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This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.

Bioinformatics of Genome Regulation and Structure II
Bioinformatics of Genome Regulation and Structure II

Author: Nikolay Kolchanov

Publisher: Springer Science & Business Media

Published: 2006-06-15

Total Pages: 545

ISBN-13: 0387294554

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The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics technologies allowing investigation of expression dynamics of large groups of genes using expression DNA chips; of proteomics methods giving the possibility to analyze protein compositions of cells, tissues, and organs, assess the dynamics of the cell proteome, and reconstruct the networks of protein-protein interactions; and of metabolomics, in particular, high resolution mass spectrometry study of cell metabolites, and distribution of metabolic fluxes in the cells with a concurrent investigation of the dynamics of thousands metabolites in an individual cell. Analysis, comprehension, and use of the tremendous volumes of experimental data reflecting the intricate processes underlying the functioning of molecular genetic systems are unfeasible in principle without the systems approach and involvement of the state-of-the-art information and computer technologies and efficient mathematical methods for data analysis and simulation of biological systems and processes. The need in solving these problems initiated the birth of a new science— postgenomic bioinformatics or systems biology in silico.

Structural Genomics and High Throughput Structural Biology
Structural Genomics and High Throughput Structural Biology

Author: Michael Sundstrom

Publisher: CRC Press

Published: 2005-08-23

Total Pages: 304

ISBN-13: 0849361435

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Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches. Based on the experience of leading international experts, Structural Genomics and High Throughput Stru

Proceedings of International Conference on Frontiers in Computing and Systems
Proceedings of International Conference on Frontiers in Computing and Systems

Author: Ram Sarkar

Publisher: Springer Nature

Published: 2023-07-31

Total Pages: 558

ISBN-13: 9819926807

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This book gathers high-quality research papers presented at the 3rd International Conference on Frontiers in Computing and Systems (COMSYS 2022) held at Indian Institute of Technology Ropar, Punjab, India, during December 19–21, 2022. The book covers research in “cyber-physical systems for real-life applications” pertaining to AI, machine learning, and data science; devices, circuits, and systems; computational biology, biomedical informatics and network medicine; communication networks, cloud computing and IoT; image, video and signal processing; and security and privacy.

Large-Scale Biomedical Science
Large-Scale Biomedical Science

Author: National Research Council

Publisher: National Academies Press

Published: 2003-07-19

Total Pages: 297

ISBN-13: 0309089123

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The nature of biomedical research has been evolving in recent years. Technological advances that make it easier to study the vast complexity of biological systems have led to the initiation of projects with a larger scale and scope. In many cases, these large-scale analyses may be the most efficient and effective way to extract functional information from complex biological systems. Large-Scale Biomedical Science: Exploring Strategies for Research looks at the role of these new large-scale projects in the biomedical sciences. Though written by the National Academies' Cancer Policy Board, this book addresses implications of large-scale science extending far beyond cancer research. It also identifies obstacles to the implementation of these projects, and makes recommendations to improve the process. The ultimate goal of biomedical research is to advance knowledge and provide useful innovations to society. Determining the best and most efficient method for accomplishing that goal, however, is a continuing and evolving challenge. The recommendations presented in Large-Scale Biomedical Science are intended to facilitate a more open, inclusive, and accountable approach to large-scale biomedical research, which in turn will maximize progress in understanding and controlling human disease.

Database Systems for Advanced Applications
Database Systems for Advanced Applications

Author: YoonJoon Lee

Publisher: Springer Science & Business Media

Published: 2004-02-24

Total Pages: 948

ISBN-13: 3540210474

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This book constitutes the refereed proceedings of the 9th International Conference on Database Systems for Advanced Applications, DASFAA 2004, held in Jeju Island, Korea in March 2004. The 60 revised full papers and 18 revised short papers presented together with 2 invited articles were carefully reviewed and seleted from 272 submissions. The papers are organized in topical sections on access methods, query processing in XML, security and integrity, query processing in temporal and spatial databases, semi-structured databases, knowledge discovery in temporal and spatial databases, XML and multimedia and knowledge discovery on the Web, query processing and optimization, classification and clustering, Web search, mobile databases, parallel and distributed databases, and multimedia databases.