The Gene

The Gene

Author: Siddhartha Mukherjee

Publisher: Simon and Schuster

Published: 2016-05-17

Total Pages: 624

ISBN-13: 1476733538

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The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).


Another Season

Another Season

Author: Gene Stallings

Publisher: St. Martin's Press

Published: 1997-08-11

Total Pages: 240

ISBN-13: 9780316811965

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Football coach Gene Stallings offers an account of his relationship with his thirty-five-year-old son Johnny, who has Down Syndrome, describing the ways in which Johnny has become an integral member of the family.


The Family Gene

The Family Gene

Author: Joselin Linder

Publisher: HarperCollins

Published: 2017-03-14

Total Pages: 245

ISBN-13: 0062378929

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A riveting medical mystery about a young woman’s quest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicine When Joselin Linder was in her twenties her legs suddenly started to swell. After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain. Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write a gripping and unforgettable exploration of family, history, and love. A compelling chronicle of survival and perseverance, The Family Gene is an important story of a young woman reckoning with her father’s death, her own mortality, and her ethical obligations to herself and those closest to her.


Origination of Organismal Form

Origination of Organismal Form

Author: Gerd B. Muller

Publisher: MIT Press

Published: 2003-01-03

Total Pages: 354

ISBN-13: 9780262134194

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A more comprehensive version of evolutionary theory that focuses as much on the origin of biological form as on its diversification. The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of biological form. Drawing on work from developmental biology, paleontology, developmental and population genetics, cancer research, physics, and theoretical biology, this book explores the multiple factors responsible for the origination of biological form. It examines the essential problems of morphological evolution—why, for example, the basic body plans of nearly all metazoans arose within a relatively short time span, why similar morphological design motifs appear in phylogenetically independent lineages, and how new structural elements are added to the body plan of a given phylogenetic lineage. It also examines discordances between genetic and phenotypic change, the physical determinants of morphogenesis, and the role of epigenetic processes in evolution. The book discusses these and other topics within the framework of evolutionary developmental biology, a new research agenda that concerns the interaction of development and evolution in the generation of biological form. By placing epigenetic processes, rather than gene sequence and gene expression changes, at the center of morphological origination, this book points the way to a more comprehensive theory of evolution.


Living with Our Genes

Living with Our Genes

Author: Dean H. Hamer

Publisher: Anchor

Published: 1999-02-16

Total Pages: 369

ISBN-13: 0385485840

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"A lucid, thought-provoking account of the case for 'nature' as a determinant of personality."—Peter D. Kramer, Author of Listening to Prozac and Should You Leave? Nowhere is the nature-nurture controversy being more arduously tested than in the labs of world-renowned molecular scientist Dean Hamer, whose cutting-edge research has indisputably linked specific genes to behavioral traits, such as anxiety, thrill-seeking, and homosexuality. The culmination of that research is this provocative book, Living with Our Genes. In it, Dr. Hamer reveals that much of our behavior—how much we eat and weigh, whether we drink or use drugs, how often we have sex—is heavily influenced by genes. His findings help explain why one brother becomes a Wall Street trader, while his sibling remains content as a librarian, or why some people like to bungee-jump, while others prefer Scrabble. Dr. Hamer also sheds light on some of the most compelling and vexing aspects of personality, such as shyness, aggression, depression, and intelligence. In the tradition of the bestselling book Listening to Prozac, Living with Our Genes is the first comprehensive investigation of the crucial link between our DNA and our behavior. "Compulsive reading, reminiscent of Jared Diamond, from a scientist who knows his stuff and communicates it well."—Kirkus Reviews "A pioneer in the field of molecular psychology, Hamer is exploring the role genes play in governing the very core of our individuality. Accessible . . . provocative."—Time "Absolutely terrific! I couldn't put it down."—Professor Robert Plomin, Social, Genetic & Developmental Psychiatry Research Center, Institute of Psychiatry


Gene Machines

Gene Machines

Author: Fran Balkwill

Publisher: CSHL Press

Published: 2002

Total Pages: 36

ISBN-13: 9780879696115

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Summary: An introduction to how genes work, including basic information about cloning and gene therapy.


The Cooking Gene

The Cooking Gene

Author: Michael W. Twitty

Publisher: HarperCollins

Published: 2018-07-31

Total Pages: 505

ISBN-13: 0062876570

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2018 James Beard Foundation Book of the Year | 2018 James Beard Foundation Book Award Winner inWriting | Nominee for the 2018 Hurston/Wright Legacy Award in Nonfiction | #75 on The Root100 2018 A renowned culinary historian offers a fresh perspective on our most divisive cultural issue, race, in this illuminating memoir of Southern cuisine and food culture that traces his ancestry—both black and white—through food, from Africa to America and slavery to freedom. Southern food is integral to the American culinary tradition, yet the question of who "owns" it is one of the most provocative touch points in our ongoing struggles over race. In this unique memoir, culinary historian Michael W. Twitty takes readers to the white-hot center of this fight, tracing the roots of his own family and the charged politics surrounding the origins of soul food, barbecue, and all Southern cuisine. From the tobacco and rice farms of colonial times to plantation kitchens and backbreaking cotton fields, Twitty tells his family story through the foods that enabled his ancestors’ survival across three centuries. He sifts through stories, recipes, genetic tests, and historical documents, and travels from Civil War battlefields in Virginia to synagogues in Alabama to Black-owned organic farms in Georgia. As he takes us through his ancestral culinary history, Twitty suggests that healing may come from embracing the discomfort of the Southern past. Along the way, he reveals a truth that is more than skin deep—the power that food has to bring the kin of the enslaved and their former slaveholders to the table, where they can discover the real America together. Illustrations by Stephen Crotts


Above the Gene, Beyond Biology

Above the Gene, Beyond Biology

Author: Jan Baedke

Publisher: University of Pittsburgh Press

Published: 2018-05-23

Total Pages: 259

ISBN-13: 0822983400

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Epigenetics is currently one of the fastest-growing fields in the sciences. Epigenetic information not only controls DNA expression but links genetic factors with the environmental experiences that influence the traits and characteristics of an individual. What we eat, where we work, and how we live affects not only the activity of our genes but that of our offspring as well. This discovery has imposed a revolutionary theoretical shift on modern biology, especially on evolutionary theory. It has helped to uncover the developmental processes leading to cancer, obesity, schizophrenia, alcoholism, and aging, and to facilitate associated medial applications such as stem cell therapy and cloning. Above the Gene, Beyond Biology explores how biologists in this booming field investigate and explain living systems. Jan Baedke offers the first comprehensive philosophical discussion of epigenetic concepts, explanations, and methodologies so that we can better understand this “epigenetic turn” in the life sciences from a philosophical perspective.


What's in Your Genes?

What's in Your Genes?

Author: Katie McKissick

Publisher: Simon and Schuster

Published: 2014-01-18

Total Pages: 256

ISBN-13: 1440567646

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Get the low-down on genetics with easy-to-understand terms and clear explanations. From interpreting dominant and recessive genes to learning about mutations, this book shows the different factors that can determine a person's DNA.


Strange Novel Worlds

Strange Novel Worlds

Author: Caroline-Isabelle Caron

Publisher: McFarland

Published: 2024-06-18

Total Pages: 296

ISBN-13: 1476653356

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Since the publication of the first James Blish novelizations of Star Trek episodes in 1967, close to 900 tie-in novels, anthologies, and omnibus editions have been published. Star Trek tie-in novels have had a significant influence on Western popular culture. The works of beloved science fiction authors have shaped the way fans understand Star Trek and its universe, and many stand as near equal builders of the Star Trek franchise, next to Gene Roddenberry, his producers, and the many creators of the later series. With such a vast and varied body of work, tie-in books form a rich and deep cultural phenomenon, the history and content of which are worthy of concerted study. Despite the enduring popularity of the franchise they are based on, no previous essay collection has ever focused on the numerous and widely diverse books of Star Trek tie-in novels. This collection does just that by examining the tie-in works as relevant literature. The essays primarily focus on tie-in books published from 1990 to 2022, and each author discusses the plot and context of separate novels while simultaneously exploring major themes such as canon vs. fanfiction and merits of the genre. The collection ends with an exploration of the continuity of this period of Star Trek as it stands following a narrative conclusion announced in 2021.