Scientific and Medical Aspects of Human Reproductive Cloning

Scientific and Medical Aspects of Human Reproductive Cloning

Author: National Research Council

Publisher: National Academies Press

Published: 2002-06-17

Total Pages: 295

ISBN-13: 0309076374

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Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.


Scientific and Medical Aspects of Human Reproductive Cloning

Scientific and Medical Aspects of Human Reproductive Cloning

Author: National Research Council

Publisher: National Academies Press

Published: 2002-05-17

Total Pages: 294

ISBN-13: 0309170001

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Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.


The Cloning Sourcebook

The Cloning Sourcebook

Author: Arlene Judith Klotzko

Publisher: Oxford University Press

Published: 2003-09-25

Total Pages: 592

ISBN-13: 0190284544

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Animal cloning has developed quickly since the birth of Dolly the sheep. Yet many of the first questions to be raised still need to be answered. What do Dolly and her fellow mouse, cow, pig, goat and monkey clones mean for science? And for society? Why do so many people respond so fearfully to cloning? What are the ethical issues raised by cloning animals, and in the future, humans? How are the makers of public policy coping with the stunning fact that an entire animal can be reconstructed from a single adult cell? And that humans might well be next? The Cloning Source Book addresses all of these questions in a way that is unique in the cloning literature, by grounding what is effectively an interdisciplinary conversation in solid science. In the first section of the book, the key scientists responsible for the early and crucial developments in cloning speak to us directly, and other scientists evaluate and comment on these developments. The second section explores the context of cloning and includes sociological, mythological, and historical perspectives on science, ethics, and policy. The authors also examine the media's treatment of the Dolly story and its aftermath, both in the United States and in Britain. The third section, on ethics, contains a broad range of papers written by some of the major commentators in the field. The fourth section addresses legal and policy issues. It features individual and collective contributions by those who have actually shaped public policy on reproductive cloning, therapeutic cloning, and similarly contentious bioethical issues in the United States, Britain, and the European Union. Animal cloning continues for agricultural and medicinal purposes, the latter in combination with transgenics. Human cloning for therapeutic purposes has recently been made legal in Britain. The goal is to produce an early embryo and then derive stem cells that are immunologically matched to the donor. Two human reproductive cloning projects have been announced, and there are almost certainly others about which we know nothing. Sooner or later a cloned human will be born. Many lessons can be learned from the cloning experience. Most importantly, there needs to be a public conversation about the permissible uses of new and morally murky technologies. Scientists, journalists, ethicists and policy makers all have roles to play, but cutting-edge science is everybody's business. The Cloning Sourcebook provides the tools required for us to participate in shaping our own futures.


Who's Afraid of Human Cloning?

Who's Afraid of Human Cloning?

Author: Gregory E. Pence

Publisher: Rowman & Littlefield

Published: 1998

Total Pages: 212

ISBN-13: 9780847687824

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Gregory Pence offers a candid look at the arguments for and against human cloning.


Clone Being

Clone Being

Author: Stephen E. Levick

Publisher: Rowman & Littlefield

Published: 2004

Total Pages: 340

ISBN-13: 9780742529908

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Most people think the risks of reproductive cloning are so high as to make trying to clone a person immoral. Even if the medical risks could be reduced greatly, many believe a clone would still risk great psychological harm, and that the practice of reproductive cloning would also be detrimental to society. Others dismiss these concerns as speculative, and point to the possible good they believe it could do. But we need not wait for the first clone to be born to systematically consider the possible psychological and social ramifications of cloning. Marshalling psychological and sociological theory and research, and drawing upon extensive clinical experiences as a psychiatrist and psychotherapist, Levick explores the various dimensions of cloning. Clone Being attempts to anticipate possible consequences for a clone, his or her 'parents' and family, and society. Psychotherapy case material enlivens and illustrates the book and the reader is helped to identify 'clone-like' aspects of his or her own experience and mental life, and of contemporary life. Through this process, the book comes to important conclusions about human nature, including the crucial roles of intimacy, sex, and sexuality for society. The clinical and scientifically grounded insights of this book should help inform the reader's ethical judgments and attitudes about cloning people.


Stem Cells and the Future of Regenerative Medicine

Stem Cells and the Future of Regenerative Medicine

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2002-01-25

Total Pages: 112

ISBN-13: 0309170427

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Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.


Human Cloning and Human Dignity

Human Cloning and Human Dignity

Author: The President's Council on Bioethics

Publisher: Createspace Independent Publishing Platform

Published: 2015-03-13

Total Pages: 0

ISBN-13: 9781508822318

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The prospect of human cloning burst into the public consciousness in 1997, following the announcement of the successful cloning of Dolly the sheep. It has since captured much attention and generated great debate, both in the United States and around the world. Many are repelled by the idea of producing children who would be genetically virtually identical to preexisting individuals, and believe such a practice unethical. But some see in such cloning the possibility to do good for infertile couples and the broader society. Some want to outlaw it, and many nations have done so. Others believe the benefits outweigh the risks and the moral concerns, or they oppose legislative interference with science and technology in the name of freedom and progress. Complicating the national dialogue about human cloning is the isolation in 1998 of human embryonic stem cells, which many scientists believe to hold great promise for understanding and treating many chronic diseases and conditions. Some scientists also believe that stem cells derived from cloned human embryos, produced explicitly for such research, might prove to be uniquely useful for studying many genetic diseases and devising novel therapies. Public reaction to this prospect has been mixed, with some Americans supporting it in the hope of advancing biomedical research and helping the sick and the suffering, while others are concerned about the instrumentalization or abuse of nascent human life and the resulting danger of moral insensitivity and degradation.


Mitochondrial Replacement Techniques

Mitochondrial Replacement Techniques

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2016-04-17

Total Pages: 201

ISBN-13: 0309388708

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Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.


Illegal Beings

Illegal Beings

Author: Kerry Lynn Macintosh

Publisher: Cambridge University Press

Published: 2005-08-01

Total Pages: 286

ISBN-13: 9780521853286

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Many people think human reproductive cloning should be a crime-some states have even outlawed it and Congress is working to enact a national ban. However, if reproductive cloning soon becomes a reality, it will be impossible to prevent infertile couples and others from choosing the technology, even if they have to break the law. While most books on cloning cover the advantages and disadvantages of cloning technology, Illegal Beings describes the pros and cons of laws against human reproductive cloning. Kerry Lynn Macintosh, an attorney with expertise in the area of law and technology, argues that the most common objections to cloning are false or exaggerated, inspiring laws that stigmatize human clones as subhuman and unworthy of existence. She applies the same reasoning that was used to invalidate racial segregation to show how anti-cloning laws, by reinforcing negative stereotypes, deprive human clones of their equal protection rights under the law. Her book creates a new topic within constitutional law: existential segregation, or the practice of discriminating by preventing the existence of a disfavored group or class. This comprehensive and novel work looks at how anti-cloning laws will hurt human clones in a fresh perspective on this controversial subject. Kerry Lynn Macintosh is a member of the Law and Technology faculty at Santa Clara University School of Law. She is the author of papers, articles, and book chapters on the law and technology and has contributed to the Harvard Journal of Law and Technology, Boston University Journal of Science and Technology Law, and Berkeley Technology Law Journal.


Human Cloning

Human Cloning

Author: Kerry Lynn Macintosh

Publisher: Cambridge University Press

Published: 2012-10-29

Total Pages: 327

ISBN-13: 1139852108

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Since Dolly the sheep was born, controversy has swirled around the technology of cloning. We recoil at the prospect of human copies, manufactured men and women, nefarious impersonators and resurrections of the dead. Such reactions have serious legal consequences: lawmakers have banned stem cell research along with the cloning of babies. But what if our minds have been playing tricks on us? What if everything we thought we knew about human cloning is rooted in intuition rather than fact? Human Cloning: Four Fallacies and their Legal Consequences is a rollicking ride through science, psychology and the law. Drawing on sources ranging from science fiction films to the Congressional Record, this book unmasks the role that psychological essentialism has played in bringing about cloning bans. It explains how hidden intuitions have caused conservatives and liberals to act contrary to their own most cherished ideals and values.