Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 1

Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 1

Author: Steven Nolan

Publisher: Thieme

Published: 2017-06-14

Total Pages: 807

ISBN-13: 3132013315

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The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.


Science of Synthesis: Asymmetric Organocatalysis Vol. 2

Science of Synthesis: Asymmetric Organocatalysis Vol. 2

Author: K. Maruoka

Publisher: Georg Thieme Verlag

Published: 2014-05-14

Total Pages: 1437

ISBN-13: 3131790210

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Asymmetric Organocatalysis 2 from the Science of Synthesis series gives an authoritative, broad overview of the field, compiled by 3 8 experts, as well as a critical presentation of the best organocatalytic and related methodologies available today for practical as ymmetric synthesis. It provides alternative, greener syntheses with simple and easily used catalysts helping avoid the use of expens ive and/or toxic metals. The reference work covers all the catalysts and reactions within the activation modes Brønsted base catalys is and Brønsted acid catalysis. Typical or general experimental procedures as well as mechanistic, technical and theoretical aspects are included, allowing the reader to clearly see how simple, clean and efficient this chemistry is. // The content of this e-book w as originally published in December 2011.


N-heterocyclic Carbenes in Catalytic Organic Synthesis

N-heterocyclic Carbenes in Catalytic Organic Synthesis

Author: Steven Nolan

Publisher: Thieme Chemistry

Published: 2017

Total Pages: 0

ISBN-13: 9783132012912

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The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.


Science of Synthesis: Catalytic Oxidation in Organic Synthesis

Science of Synthesis: Catalytic Oxidation in Organic Synthesis

Author: Kilian Muñiz

Publisher: Thieme

Published: 2018-03-23

Total Pages: 1425

ISBN-13: 3132012718

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The development of catalytic systems for the oxidation of organic compounds continues to be of great importance. There is an ongoing and increasing demand for methods that are selective, proceed under mild conditions, and adhere to green chemistry principles. "Science of Synthesis: Catalytic Oxidation in Organic Synthesis" includes the latest developments in the field, as well as selective coverage of more well-established methods. Systems based on metal catalysts, organocatalysts, and biomimetic oxidation are covered, and there is a particular focus on asymmetric processes. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.


N-Heterocyclic Carbenes in Organocatalysis

N-Heterocyclic Carbenes in Organocatalysis

Author: Akkattu T. Biju

Publisher: John Wiley & Sons

Published: 2019-01-07

Total Pages: 440

ISBN-13: 3527809058

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Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.


Science of Synthesis: Dual Catalysis in Organic Synthesis 1

Science of Synthesis: Dual Catalysis in Organic Synthesis 1

Author: G. A. Molander

Publisher: Thieme

Published: 2020-05-22

Total Pages: 490

ISBN-13: 3132429783

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The field of dual catalysis has developed rapidly over the last decade, and these volumes define its impact on organic synthesis. The most important, basic concepts of synergistic, dual catalytic cycles are introduced, providing newcomers to the field with reliable information on this new approach to facilitating the synthesis of organic molecules. Background information and reliable procedures for challenging transformations in synthesis are presented, applying the concept of cooperative dual catalysis as a means of increasing molecular complexity in the most efficient manner. The most useful, practical, and reliable methods for dual catalysis combining metal catalysts, organocatalysts, photocatalysts, and biocatalysts are presented.


Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis

Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis

Author: E. Fernández

Publisher: Thieme

Published: 2020-05-22

Total Pages: 582

ISBN-13: 3132429732

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The widespread use of organoboron compounds justifies the efforts devoted to their synthesis, as well as toward developing an understanding of their reactivity. The nature of the mono- or diboron species is of paramount importance in determining the reversible covalent binding properties of the boron atom with both nucleophiles and electrophiles. By wedding the rich chemical potential of organoboron compounds to the ubiquity of organic scaffolds, advanced borylation reactions have the potential to open unprecedented synthetic alternatives, and new knowledge in the field should encourage chemists to use organoboron compounds. In this volume, the main objective is to provide a collection of the most useful, practical, and reliable methods, reported mainly within the last decade, for boron activation and boron reactivity. The volume covers the main concepts of organoboron compounds and includes experimental procedures, enabling newcomers to the field the instant and reliable application of the new tools in synthesis. Rather than aiming for a comprehensive coverage, the most advanced solutions for challenging transformations are introduced. To this end, a team of pioneers and leaders in the field have been assembled who discuss both the practical and conceptual aspects of this rapidly growing field.


Non-Metal Catalyzed Synthesis

Non-Metal Catalyzed Synthesis

Author: Yunfei Du

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2023-12-04

Total Pages: 360

ISBN-13: 3110985470

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Non-metal catalysis may provide new and green methods for obtaining bioactive heterocycles. Many catalysts contain metals, which can be toxic, energy intensive to remove, and require mining of the source materials. By utilizing metal-free catalysts we avoid these issues. This book explores the use of non-metal catalysts when synthesizing various heterocyclic structures with bioactivity.


Science of Synthesis: Houben-Weyl Methods of Molecular Transformations Vol. 20b

Science of Synthesis: Houben-Weyl Methods of Molecular Transformations Vol. 20b

Author: James S. Panek

Publisher: Georg Thieme Verlag

Published: 2014-05-14

Total Pages: 1925

ISBN-13: 3131781319

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Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.// The content of this e-book was originally published in October 2006.