The procedures were implemented primarily by the information products department of the applications division. The statistical research division, core development division, host systems division, and internal database department also made significant contributions. Program development includes designing, programming, debugging, and supporting the software as well as providing preliminary documentation and reviewing later documentation.
Statistical Concepts—A Second Course presents the last 10 chapters from An Introduction to Statistical Concepts, Fourth Edition. Designed for second and upper-level statistics courses, this book highlights how statistics work and how best to utilize them to aid students in the analysis of their own data and the interpretation of research results. In this new edition, Hahs-Vaughn and Lomax discuss sensitivity, specificity, false positive and false negative errors. Coverage of effect sizes has been expanded upon and more organizational features (to summarize key concepts) have been included. A final chapter on mediation and moderation has been added for a more complete presentation of regression models. In addition to instructions and screen shots for using SPSS, new to this edition is annotated script for using R. This book acts as a clear and accessible instructional tool to help readers fully understand statistical concepts and how to apply them to data. It is an invaluable resource for students undertaking a course in statistics in any number of social science and behavioral science disciplines.
Easily Use SAS to Produce Your Graphics Diagrams, plots, and other types of graphics are indispensable components in nearly all phases of statistical analysis, from the initial assessment of the data to the selection of appropriate statistical models to the diagnosis of the chosen models once they have been fitted to the data. Harnessing the full graphics capabilities of SAS, A Handbook of Statistical Graphics Using SAS ODS covers essential graphical methods needed in every statistician’s toolkit. It explains how to implement the methods using SAS 9.4. The handbook shows how to use SAS to create many types of statistical graphics for exploring data and diagnosing fitted models. It uses SAS’s newer ODS graphics throughout as this system offers a number of advantages, including ease of use, high quality of results, consistent appearance, and convenient semiautomatic graphs from the statistical procedures. Each chapter deals graphically with several sets of example data from a wide variety of areas, such as epidemiology, medicine, and psychology. These examples illustrate the use of graphic displays to give an overview of data, to suggest possible hypotheses for testing new data, and to interpret fitted statistical models. The SAS programs and data sets are available online.
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
