Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.
Research Paper (postgraduate) from the year 2007 in the subject Medicine - Dentistry, University of Mosul (Dental college), language: English, abstract: Aims: To study the effect of Beta–adrenergic agonist (salbutamol) and Beta adrenergic antagonist (atenolol) on salivary protein concentration and to study relation between salivary protein concentration and oral health. Materials and Methods: This study was carried out on 45 individuals; 15 individuals of them were apparently healthy with no history of systemic diseases and represent a control group, the second group which comprised 15 subjects were given adrenergic agonist drug (salbutamol) for treatment of asthma, and third group (15 individuals) were given adrenegic antagonist drug (atenolol) for treatment of hypertension. subjects were selected from the out patients attending Oral Surgery Department, College of Dentistry, University of Mosul. The samples of saliva were collected using spitting method and oral hygiene index simplified was recorded for each individual and total protein concentration of these saliva samples were determined. Its relation to oral health was measured according to simplified oral hygiene index by Greene and Vermillion. Results: The results of this study revealed that in all study groups, significant differences were present for both salivary protein concentration and oral health scores and there is correlation between salivary protein concentration and oral health in patients receiving atenolol. Conclusions: Chronic treatment with adrenergic agonist and antagonist drugs, resulted in changes in salivary protein concentration and those will affect the oral health of patients treated by these drugs.
Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopathological processes occurring in organisms, since saliva has been shown to contain molecular and bacterial compounds that can change in response to local and systemic pathologies. Furthermore, the interest of saliva as a diagnostic, prognostic and monitoring biofluid is forced by its non-invasive nature being of easy and inexpensive sampling, involving only minimal discomfort and allowing the collection of multiple/repeated specimens at anytime, anywhere and without need for specialized staff. In this contributed volume, the authors bring together, summarize and reflect the generated knowledge about saliva as a source of biomarkers for health and welfare evaluation in humans and animal models. This volume also highlights the importance of confounding factors, such as sampling methods, flow, total protein content, contamination, or storage. This book will serve as a manual for graduates, practitioners and researchers by providing general ideas about the possibilities and utilities of saliva in clinical practice or investigation, and indicating the main cautions each should have in mind before saliva usage.
This is the first book for some years that provides a comprehensive overview of food oral processing including the biomechanics of swallowing, the biophysics of mouthfeel and texture as well as the biochemistry of flavours and how food microstructures can be manipulated.
Xerostomia, more commonly called dry mouth, affects an estimated 20 percent of adults worldwide and can severely diminish one’s quality of life. Dry Mouth, the Malevolent Symptom: A Clinical Guide relies on evidence-based research to provide an introductory primer on oral dryness and the modalities available to treat it. The book describes the varied etiology of the disease, but emphasizes clinical protocols and step-by-step procedures for diagnosis and treatment planning. Dry Mouth is a user-friendly manual guiding clinicians through identifying and managing this common condition. Causes including radiotherapy, chemotherapy, systemic diseases, polypharmacy, and the natural progression of aging are discussed in conjunction with the clinical symptoms and signs associated with each one. Multiple avenues for treatment are presented, highlighting salivary stimulation and supplementation techniques, pharmacologic aids, and critically required oral therapy. Although intended primarily for the professionals that treat those affected by xerostomia, Dry Mouth may also be of interest to sufferers of this condition.
