This book continues where DOE Simplified leaves off in Chapter 8 with an introduction to "Response Surface Methods [RSM] for Optimization." It presents this advanced tool for design of experiments (DOE) in a way that anyone with a minimum of technical training can understand and appreciate. Unlike any other book of its kind, RSM Simplified keeps formulas to a minimum—making liberal use of figures, charts, graphs and checklists. It also offers many relevant examples, amusing and fun do-it-yourself exercises.
The global response to the COVID-19 pandemic is the greatest science policy failure in a generation. We knew this was coming. Warnings about the threat of a new pandemic have been made repeatedly since the 1980s and it was clear in January that a dangerous new virus was causing a devastating human tragedy in China. And yet the world ignored the warnings. Why? In this short and hard-hitting book, Richard Horton, editor of the medical journal The Lancet, scrutinizes the actions that governments around the world took – and failed to take – as the virus spread from its origins in Wuhan to the global pandemic that it is today. He shows that many Western governments and their scientific advisors made assumptions about the virus and its lethality that turned out to be mistaken. Valuable time was lost while the virus spread unchecked, leaving health systems unprepared for the avalanche of infections that followed. Drawing on his own scientific and medical expertise, Horton outlines the measures that need to be put in place, at both national and international levels, to prevent this kind of catastrophe from happening again. Were supposed to be living in an era where human beings have become the dominant influence on the environment, but COVID-19 has revealed the fragility of our societies and the speed with which our systems can come crashing down. We need to learn the lessons of this pandemic and we need to learn them fast because the next pandemic may arrive sooner than we think.
'I am a junior doctor. It is 4 a.m. I have run arrest calls, treated life-threatening bleeding, held the hand of a young woman dying of cancer, scuttled down miles of dim corridors wanting to sob with sheer exhaustion, forgotten to eat, forgotten to drink, drawn on every fibre of strength that I possess to keep my patients safe from harm.' How does it feel to be spat out of medical school into a world of pain, loss and trauma that you feel wholly ill-equipped to handle? To be a medical novice who makes decisions which - if you get them wrong - might forever alter, or end, a person's life? To toughen up the hard way, through repeated exposure to life-and-death situations, until you are finally a match for them? In this heartfelt, deeply personal account of life as a junior doctor in today's health service, former television journalist turned doctor, Rachel Clarke, captures the extraordinary realities of ordinary life on the NHS front line. From the historic junior doctor strikes of 2016 to the 'humanitarian crisis' declared by the Red Cross, the overstretched health service is on the precipice, calling for junior doctors to draw on extraordinary reserves of what compelled them into medicine in the first place - and the value the NHS can least afford to lose - kindness. Your Life in My Hands is at once a powerful polemic on the systematic degradation of Britain's most vital public institution, and a love letter of optimism and hope to that same health service and those who support it. This extraordinary memoir offers a glimpse into a life spent between the operating room and the bedside, the mortuary and the doctors' mess, telling powerful truths about today's NHS frontline, and capturing with tenderness and humanity the highs and lows of a new doctor's first steps onto the wards in the context of a health service at breaking point - and what it means to be entrusted with carrying another's life in your hands. 'Eloquent and moving' - Henry Marsh 'There have been many books written by young doctors... but none comes close to Clarke's' - Sunday Times 'From the very heart of the NHS comes this brilliant insight into the continuing crisis in the health service. Rachel Clarke writes as the accomplished journalist she once was and as the leading junior doctor she now is - writing with humanity and compassion that at times reduced me to tears.' - Jon Snow, Channel 4 News 'Dr Clarke has written a blockbuster, a page-turner, a tear-jerker. This is a "from-the-heart" front-line account of the human cost of the wanton erosion of a magnificent ideal - healthcare free at the point of need, funded through public taxation, available to all - made real in the UK for near 70 years. It is a love-song for the wonderful National Health Service that has embodied - to an extent equalled nowhere in the world - the principle that healthcare is not a commodity but a great duty of state.' - Prof. Neena Modi, President of the Royal College of Paediatrics and Child Health 'A powerful account of life on the NHS frontline. If only Theresa May and Jeremy Hunt could see the passion behind the people in the NHS, they might stop treating them as the enemy, and understand that without them we don't have an NHS worth the name.' - Alastair Campbell
Praise for the Third Edition: “This new third edition has been substantially rewritten and updated with new topics and material, new examples and exercises, and to more fully illustrate modern applications of RSM.” - Zentralblatt Math Featuring a substantial revision, the Fourth Edition of Response Surface Methodology: Process and Product Optimization Using Designed Experiments presents updated coverage on the underlying theory and applications of response surface methodology (RSM). Providing the assumptions and conditions necessary to successfully apply RSM in modern applications, the new edition covers classical and modern response surface designs in order to present a clear connection between the designs and analyses in RSM. With multiple revised sections with new topics and expanded coverage, Response Surface Methodology: Process and Product Optimization Using Designed Experiments, Fourth Edition includes: Many updates on topics such as optimal designs, optimization techniques, robust parameter design, methods for design evaluation, computer-generated designs, multiple response optimization, and non-normal responses Additional coverage on topics such as experiments with computer models, definitive screening designs, and data measured with error Expanded integration of examples and experiments, which present up-to-date software applications, such as JMP®, SAS, and Design-Expert®, throughout An extensive references section to help readers stay up-to-date with leading research in the field of RSM An ideal textbook for upper-undergraduate and graduate-level courses in statistics, engineering, and chemical/physical sciences, Response Surface Methodology: Process and Product Optimization Using Designed Experiments, Fourth Edition is also a useful reference for applied statisticians and engineers in disciplines such as quality, process, and chemistry.
Looking into the Well: Supervision of Spiritual Directors is the first book-length treatment of the supervision and development of spiritual directors.
This is the eBook version of the printed book. If the print book includes a CD-ROM, this content is not included within the eBook version. The most complete guide to Cisco Catalyst(r) switch network design, operation, and configuration Master key foundation topics such as high-speed LAN technologies, LAN segmentation, bridging, the Catalyst command-line environment, and VLANs Improve the performance of your campus network by utilizing effective Cisco Catalyst design, configuration, and troubleshooting techniques Benefit from the most comprehensive coverage of Spanning-Tree Protocol, including invaluable information on troubleshooting common Spanning Tree problems Master trunking concepts and applications, including ISL, 802.1Q, LANE, and MPOA Understand when and how to utilize Layer 3 switching techniques for maximum effect Understand Layer 2 and Layer 3 switching configuration with the Catalyst 6000 family, including coverage of the powerful MSFC Native IOS Mode Cisco LAN Switchingprovides the most comprehensive coverage of the best methods for designing, utilizing, and deploying LAN switching devices and technologies in a modern campus network. Divided into six parts, this book takes you beyond basic switching concepts by providing an array of proven design models, practical implementation solutions, and troubleshooting strategies. Part I discusses important foundation issues that provide a context for the rest of the book, including Fast and Gigabit Ethernet, routing versus switching, the types of Layer 2 switching, the Catalyst command-line environment, and VLANs. Part II presents the most detailed discussion of Spanning-Tree Protocol in print, including common problems, troubleshooting, and enhancements, such as PortFast, UplinkFast, BackboneFast, and PVST+. Part III examines the critical issue of trunk connections, the links used to carry multiple VLANs through campus networks. Entire chapters are dedicated to LANE and MPOA. Part IV addresses advanced features, such as Layer 3 switching, VTP, and CGMP and IGMP. Part V covers real-world campus design and implementation issues, allowing you to benefit from the collective advice of many LAN switching experts. Part VI discusses issues specific to the Catalyst 6000/6500 family of switches, including the powerful Native IOS Mode of Layer 3 switching. Several features in Cisco LAN Switchingare designed to reinforce concepts covered in the book and to help you prepare for the CCIE exam. In addition to the practical discussion of advanced switching issues, this book also contains case studies that highlight real-world design, implementation, and management issues, as well as chapter-ending review questions and exercises. This book is part of the Cisco CCIE Professional Development Series from Cisco Press, which offers expert-level instruction on network design, deployment, and support methodologies to help networking professionals manage complex networks and prepare for CCIE exams.
This IBM® Redbooks® publication consolidates, in one document, detailed descriptions of the hardware configurations and options offered as part of the IBM System Storage DS5000 families of products. This edition covers updates and additional functions available with the IBM System Storage DS® Storage Manager Version 10.77 (firmware level 7.77). This book presents the concepts and functions used in planning and managing the storage servers, such as multipathing and path failover. The book offers a step-by-step guide to using the Storage Manager to create arrays, logical drives, and other basic (as well as advanced) management tasks. This publication also contains practical information about diagnostics and troubleshooting, and includes practical examples of how to use scripts and the command-line interface. This publication is intended for customers, IBM Business Partners, and IBM technical professionals who want to learn more about the capabilities and advanced functions of the DS5000 series of storage servers with Storage Manager Software V10.77. It also targets those who have a DS5000 storage subsystem and need detailed advice about how to configure it. This book is designed specifically to address the hardware features and configuration of the IBM System Storage DS5000 family and can be used in conjunction with the following IBM Redbooks publications: IBM System Storage DS5000 Series Implementation and Best Practices Guide, SG24-8024 IBM System Storage DS Storage Manager Copy Services Guide, SG24-7822
With organizations and individuals increasingly dependent on the Web, the need for competent, well-trained Web developers and maintainers is growing. Helping readers master Web development, Dynamic Web Programming and HTML5 covers specific Web programming languages, APIs, and coding techniques and provides an in-depth understanding of the underlying concepts, theory, and principles. The author leads readers through page structuring, page layout/styling, user input processing, dynamic user interfaces, database-driven websites, and mobile website development. After an overview of the Web and Internet, the book focuses on the new HTML5 and its associated open Web platform standards. It covers the HTML5 markup language and DOM, new elements for structuring Web documents and forms, CSS3, and important JavaScript APIs associated with HTML5. Moving on to dynamic page generation and server-side programming with PHP, the text discusses page templates, form processing, session control, user login, database access, and server-side HTTP requests. It also explores more advanced topics such as XML and PHP/MySQL. Suitable for a one- or two-semester course at the advanced undergraduate or beginning graduate level, this comprehensive and up-to-date guide helps readers learn modern Web technologies and their practical applications. Numerous examples illustrate how the programming techniques and other elements work together to achieve practical goals. Online Resource Encouraging hands-on practice, the book’s companion website at http://dwp.sofpower.com helps readers gain experience with the technologies and techniques involved in building good sites. Maintained by the author, the site offers: Live examples organized by chapter and cross-referenced in the text Programs from the text bundled in a downloadable code package Searchable index and appendices Ample resource listings and information updates
